modafinil has been researched along with Nerve Degeneration in 3 studies
Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Modafinil treatment dose-dependently (10-100 mg/kg) counteracted the hemitransection-induced disappearance of nigral TH-immunoreactive nerve cell body profiles and neostriatal TH-immunoreactive nerve terminal profiles." | 1.29 | The vigilance-promoting drug modafinil counteracts the reduction of tyrosine hydroxylase immunoreactivity and of dopamine stores in nigrostriatal dopamine neurons in the male rat after a partial transection of the dopamine pathway. ( Agnati, LF; Altamimi, U; Andbjer, B; Finnman, UB; Fuxe, K; Goldstein, M; Janson, AM; Rosén, L; Ueki, A, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Vliet, SA | 1 |
| van Vlieta, SA | 1 |
| Blezer, EL | 1 |
| Jongsma, MJ | 1 |
| Vanwersch, RA | 1 |
| Olivier, B | 1 |
| Philippens, IH | 1 |
| Ueki, A | 1 |
| Rosén, L | 2 |
| Andbjer, B | 1 |
| Finnman, UB | 2 |
| Altamimi, U | 1 |
| Janson, AM | 2 |
| Goldstein, M | 2 |
| Agnati, LF | 2 |
| Fuxe, K | 2 |
| Tanganelli, S | 1 |
| Morari, M | 1 |
3 other studies available for modafinil and Nerve Degeneration