modafinil has been researched along with Mood Disorders in 5 studies
Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.
Mood Disorders: Those disorders that have a disturbance in mood as their predominant feature.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Relative to baseline, patients reported lower fatigue severity (CIS) and better motivation (CIS) in both the modafinil (P = ." | 9.17 | The effect of modafinil on fatigue, cognitive functioning, and mood in primary brain tumor patients: a multicenter randomized controlled trial. ( Boele, FW; Cleijne, W; de Groot, M; Douw, L; Heimans, JJ; Klein, M; Reijneveld, JC; Taphoorn, MJ; van Thuijl, HF, 2013) |
| " Relative to baseline, patients reported lower fatigue severity (CIS) and better motivation (CIS) in both the modafinil (P = ." | 5.17 | The effect of modafinil on fatigue, cognitive functioning, and mood in primary brain tumor patients: a multicenter randomized controlled trial. ( Boele, FW; Cleijne, W; de Groot, M; Douw, L; Heimans, JJ; Klein, M; Reijneveld, JC; Taphoorn, MJ; van Thuijl, HF, 2013) |
| "Adult affective disorder patients, whether unipolar or bipolar, can use modafinil to relieve symptoms of depression, including fatigue and sleepiness, without risking a switch in their mood or developing tolerance or abuse of this medication." | 3.73 | Absence of mood switch with and tolerance to modafinil: a replication study from a large private practice. ( Nasr, S; Steiner, K; Wendt, B, 2006) |
| "Modafinil has proven to be effective in the treatment of residual symptoms of unipolar and bipolar depression such as fatigue, excessive sleepiness and some cognitive impairment." | 2.66 | The role of eugeroics in the treatment of affective disorders. ( Cubała, WJ; Urban, AE, 2020) |
| "Modafinil was the most common drug used as a first-line treatment (93%) and in combination therapy (70%)." | 1.48 | Effectiveness and side-effect profile of stimulant therapy as monotherapy and in combination in the central hypersomnias in clinical practice. ( D'ancona, G; Drakatos, P; Kent, BD; Leschziner, GD; Nesbitt, A; Patel, K; Rosenzweig, I; Selsick, H; Steier, J; Thakrar, C; Williams, AJ, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Urban, AE | 1 |
| Cubała, WJ | 1 |
| Thakrar, C | 1 |
| Patel, K | 1 |
| D'ancona, G | 1 |
| Kent, BD | 1 |
| Nesbitt, A | 1 |
| Selsick, H | 1 |
| Steier, J | 1 |
| Rosenzweig, I | 1 |
| Williams, AJ | 1 |
| Leschziner, GD | 1 |
| Drakatos, P | 1 |
| Boele, FW | 1 |
| Douw, L | 1 |
| de Groot, M | 1 |
| van Thuijl, HF | 1 |
| Cleijne, W | 1 |
| Heimans, JJ | 1 |
| Taphoorn, MJ | 1 |
| Reijneveld, JC | 1 |
| Klein, M | 1 |
| Russo, M | 1 |
| Maher, C | 1 |
| Campbell, W | 1 |
| Nasr, S | 1 |
| Wendt, B | 1 |
| Steiner, K | 1 |
1 review available for modafinil and Mood Disorders
| Article | Year |
|---|---|
The role of eugeroics in the treatment of affective disorders.
Topics: Adult; Antidepressive Agents; Central Nervous System Stimulants; Depressive Disorder, Major; Evidenc | 2020 |
1 trial available for modafinil and Mood Disorders
| Article | Year |
|---|---|
The effect of modafinil on fatigue, cognitive functioning, and mood in primary brain tumor patients: a multicenter randomized controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Benzhydryl Compounds; Brain Neoplasms; Cognition Disorders; Cross-Ov | 2013 |
3 other studies available for modafinil and Mood Disorders
| Article | Year |
|---|---|
Effectiveness and side-effect profile of stimulant therapy as monotherapy and in combination in the central hypersomnias in clinical practice.
Topics: Adult; Central Nervous System Stimulants; Drug Therapy, Combination; Female; Follow-Up Studies; Head | 2018 |
Cosmetic neurology: the controversy over enhancing movement, mentation, and mood.
Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Humans; Judgment; Military Medicine; Modafi | 2005 |
Absence of mood switch with and tolerance to modafinil: a replication study from a large private practice.
Topics: Adult; Aged; Aged, 80 and over; Benzhydryl Compounds; Central Nervous System Stimulants; Drug Tolera | 2006 |