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modafinil and Liver Failure, Acute

modafinil has been researched along with Liver Failure, Acute in 1 studies

Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.

Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.

Research Excerpts

ExcerptRelevanceReference
"To investigate the effect of diazepam and modafinil on acute hepatic failure in mice."7.73[Effect of diazepam and modafinil on acute hepatic failure in mice]. ( Peng, SF; Tan, DM; Zhu, HP, 2005)
"To investigate the effect of diazepam and modafinil on acute hepatic failure in mice."3.73[Effect of diazepam and modafinil on acute hepatic failure in mice]. ( Peng, SF; Tan, DM; Zhu, HP, 2005)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhu, HP1
Tan, DM1
Peng, SF1

Other Studies

1 other study available for modafinil and Liver Failure, Acute

ArticleYear
[Effect of diazepam and modafinil on acute hepatic failure in mice].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2005, Volume: 30, Issue:3

    Topics: Animals; Benzhydryl Compounds; Diazepam; Galactosamine; Lipopolysaccharides; Liver; Liver Failure, A

2005