modafinil has been researched along with Labhart-Willi Syndrome in 2 studies
Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Excessive daytime sleepiness is a frequent and a highly disruptive symptom to the daily routine of children with Prader-Willi Syndrome (PWS) and their families." | 5.37 | Efficacy of modafinil on excessive daytime sleepiness in Prader-Willi syndrome. ( De Cock, VC; Diene, G; Kieffer, I; Masson, VD; Mimoun, E; Molinas, C; Tauber, M; Tiberge, M, 2011) |
| "Long-term modafinil therapy may ameliorate the sleep disturbances of Prader-Willi syndrome and should be the focus of future clinical trials." | 3.80 | Prader-Willi syndrome, excessive daytime sleepiness, and narcoleptic symptoms: a case report. ( Couch, R; Foulds, JL; Haqq, AM; Rubin, D; Weselake, SV; Witmans, MB, 2014) |
| "Excessive daytime sleepiness is a frequent and a highly disruptive symptom to the daily routine of children with Prader-Willi Syndrome (PWS) and their families." | 1.37 | Efficacy of modafinil on excessive daytime sleepiness in Prader-Willi syndrome. ( De Cock, VC; Diene, G; Kieffer, I; Masson, VD; Mimoun, E; Molinas, C; Tauber, M; Tiberge, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weselake, SV | 1 |
| Foulds, JL | 1 |
| Couch, R | 1 |
| Witmans, MB | 1 |
| Rubin, D | 1 |
| Haqq, AM | 1 |
| De Cock, VC | 1 |
| Diene, G | 1 |
| Molinas, C | 1 |
| Masson, VD | 1 |
| Kieffer, I | 1 |
| Mimoun, E | 1 |
| Tiberge, M | 1 |
| Tauber, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-Blind, Controlled Trial of Bright Light Therapy on All-Cause Excessive Daytime Sleepiness in Prader-Willi Syndrome[NCT05939453] | 30 participants (Anticipated) | Interventional | 2023-10-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for modafinil and Labhart-Willi Syndrome
| Article | Year |
|---|---|
Prader-Willi syndrome, excessive daytime sleepiness, and narcoleptic symptoms: a case report.
Topics: Benzhydryl Compounds; Child; Disorders of Excessive Somnolence; Female; Humans; Modafinil; Narcoleps | 2014 |
Efficacy of modafinil on excessive daytime sleepiness in Prader-Willi syndrome.
Topics: Adolescent; Adult; Benzhydryl Compounds; Central Nervous System Stimulants; Child; Disorders of Exce | 2011 |