modafinil has been researched along with Inflammation in 4 studies
Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Modafinil has significant anti-inflammation and anti-oxidation effects." | 7.96 | Modafinil ameliorated pancreatic injury and inflammation through upregulating SNIP1. ( Huang, B; Jiang, X; Li, S; Lu, Y; Qiao, Z; Qin, A; Wu, J, 2020) |
| "Modafinil, an FDA approved wakefulness drug prescribed to narcolepsy patients, has recently been shown to have anti-inflammatory effects and provides protection against neuroinflammation." | 7.88 | Modafinil attenuates inflammation via inhibiting Akt/NF-κB pathway in apoE-deficient mouse model of atherosclerosis. ( Chen, D; Han, J; Liu, D; Zhu, Y, 2018) |
| " Modafinil has significant anti-inflammation and anti-oxidation effects." | 3.96 | Modafinil ameliorated pancreatic injury and inflammation through upregulating SNIP1. ( Huang, B; Jiang, X; Li, S; Lu, Y; Qiao, Z; Qin, A; Wu, J, 2020) |
| "Modafinil, an FDA approved wakefulness drug prescribed to narcolepsy patients, has recently been shown to have anti-inflammatory effects and provides protection against neuroinflammation." | 3.88 | Modafinil attenuates inflammation via inhibiting Akt/NF-κB pathway in apoE-deficient mouse model of atherosclerosis. ( Chen, D; Han, J; Liu, D; Zhu, Y, 2018) |
| "Rats treated with Modafinil after the trauma had a statistically significant higher Garcia Test Score (P<0." | 1.91 | Modafinil attenuates the neuroinflammatory response after experimental traumatic brain injury. ( Bozkurt, I; Cingirt, M; Gulbahar, O; Guvenc, Y; Kepoglu, U; Ozcerezci, T; Ozturk, Y; Senturk, S; Yaman, ME, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ozturk, Y | 1 |
| Bozkurt, I | 1 |
| Guvenc, Y | 1 |
| Kepoglu, U | 1 |
| Cingirt, M | 1 |
| Gulbahar, O | 1 |
| Ozcerezci, T | 1 |
| Senturk, S | 1 |
| Yaman, ME | 1 |
| Wu, J | 1 |
| Lu, Y | 1 |
| Qin, A | 1 |
| Li, S | 1 |
| Huang, B | 1 |
| Jiang, X | 1 |
| Qiao, Z | 1 |
| Han, J | 1 |
| Chen, D | 1 |
| Liu, D | 1 |
| Zhu, Y | 1 |
| Raineri, M | 1 |
| Gonzalez, B | 1 |
| Goitia, B | 1 |
| Garcia-Rill, E | 1 |
| Krasnova, IN | 1 |
| Cadet, JL | 1 |
| Urbano, FJ | 1 |
| Bisagno, V | 1 |
4 other studies available for modafinil and Inflammation
| Article | Year |
|---|---|
Modafinil attenuates the neuroinflammatory response after experimental traumatic brain injury.
Topics: Animals; Anti-Inflammatory Agents; Brain Injuries, Traumatic; Caspase 3; Disease Models, Animal; Inf | 2023 |
Modafinil ameliorated pancreatic injury and inflammation through upregulating SNIP1.
Topics: Acute Disease; Animals; Cell Line; Ceruletide; Inflammation; Modafinil; Pancreatitis; Rats; RNA-Bind | 2020 |
Modafinil attenuates inflammation via inhibiting Akt/NF-κB pathway in apoE-deficient mouse model of atherosclerosis.
Topics: Animals; Anti-Inflammatory Agents; Apolipoproteins E; Atherosclerosis; Benzhydryl Compounds; Cell Pr | 2018 |
Modafinil abrogates methamphetamine-induced neuroinflammation and apoptotic effects in the mouse striatum.
Topics: Animals; Apoptosis; Benzhydryl Compounds; Corpus Striatum; Dopamine Plasma Membrane Transport Protei | 2012 |