modafinil has been researched along with Inadequate Sleep in 85 studies
Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the impact of modafinil on "free" and "cued" recall of clinical information in fatigued but nonsleep-deprived clinicians." | 9.22 | Structured cues or modafinil for fatigue amelioration in clinicians? A double-blind, randomized controlled trial of critical clinical information recall in fatigued clinicians. ( Darzi, A; Flindall, I; Goodship, J; Leff, DR; Sugden, C, 2016) |
| "The extent to which modafinil and caffeine reverse fatigue effects (defined as performance decrements with time on task) during total sleep deprivation was investigated." | 7.72 | Modafinil vs. caffeine: effects on fatigue during sleep deprivation. ( Balkin, TJ; Belenky, G; Kautz, MA; Thorne, DR; Wesensten, NJ, 2004) |
| "Modafinil can effectively reduced the subjective fatigue and sleepiness levels during SD." | 7.72 | [Effects of modafinil on visual and auditory reaction abilities and subjective fatigue level during 48 h sleep deprivation]. ( Li, T; Li, YF; Tang, GX; Wei, SH; Xin, YM; Zhan, H, 2003) |
| "To evaluate the impact of modafinil on "free" and "cued" recall of clinical information in fatigued but nonsleep-deprived clinicians." | 5.22 | Structured cues or modafinil for fatigue amelioration in clinicians? A double-blind, randomized controlled trial of critical clinical information recall in fatigued clinicians. ( Darzi, A; Flindall, I; Goodship, J; Leff, DR; Sugden, C, 2016) |
| "Modafinil is an alerting substance which has been used successfully to treat narcolepsy." | 5.08 | Effect of modafinil on plasma melatonin, cortisol and growth hormone rhythms, rectal temperature and performance in healthy subjects during a 36 h sleep deprivation. ( Bastuji, H; Boissy, I; Brun, J; Chamba, G; Claustrat, B; Girard, P; Khalfallah, Y; Sassolas, G, 1998) |
| " On the contrary, suppression of EEG delta power using a wake-promoting agent modafinil significantly attenuated mechanical allodynia." | 3.96 | High cortical delta power correlates with aggravated allodynia by activating anterior cingulate cortex GABAergic neurons in neuropathic pain mice. ( Ge, J; Hong, ZY; Huang, ZL; Lazarus, M; Li, YD; Luo, YJ; Qu, WM; Wang, J; Xu, W, 2020) |
| " Withdrawal of the narcolepsy treatment and initiation of haloperidol 1 mg/day (the only antipsychotic treatment she could tolerate) improved the delusions, hallucinations and dysphoria but worsened the narcolepsy symptoms." | 3.85 | Narcolepsy-cataplexy and psychosis: a case study. ( Arango-Lopez, C; Canellas-Dols, F; Delgado, C; Peraita-Adrados, R, 2017) |
| "Although modafinil did not sustain performance at predeprivation levels, the present study suggests that modafinil should be considered for the military's armament of short-term fatigue countermeasures." | 3.72 | Modafinil's effects on simulator performance and mood in pilots during 37 h without sleep. ( Brown, DL; Caldwell, JA; Caldwell, JL; Smith, JK, 2004) |
| "The extent to which modafinil and caffeine reverse fatigue effects (defined as performance decrements with time on task) during total sleep deprivation was investigated." | 3.72 | Modafinil vs. caffeine: effects on fatigue during sleep deprivation. ( Balkin, TJ; Belenky, G; Kautz, MA; Thorne, DR; Wesensten, NJ, 2004) |
| "Modafinil can effectively reduced the subjective fatigue and sleepiness levels during SD." | 3.72 | [Effects of modafinil on visual and auditory reaction abilities and subjective fatigue level during 48 h sleep deprivation]. ( Li, T; Li, YF; Tang, GX; Wei, SH; Xin, YM; Zhan, H, 2003) |
| "Compared with before sleep deprivation, the amplitudes of the event-related potentials (ERPs) increased in the N2 component and decreased in the P3 component after sleep deprivation in the placebo condition." | 3.11 | Modafinil ameliorates the decline in pronunciation-related working memory caused by 36-h acute total sleep deprivation: An ERP study. ( Dai, C; Lv, J; Peng, Z; Shao, Y; Song, T; Wang, L; Xu, L; Xu, M; Yang, X, 2022) |
| "Individual responses to the effects of inadequate sleep have been well documented; some people are more vulnerable to the effects of sleep loss than others." | 2.94 | Differential effects of modafinil on performance of low-performing and high-performing individuals during total sleep deprivation. ( Caldwell, JL; Kunkle, CL; Schroeder, VM; Stephenson, HG, 2020) |
| "Modafinil is an eugeroic drug that has been examined to maintain or recover wakefulness, alertness, and cognitive performance when sleep deprived." | 2.82 | A State-of-the-Art Review on the Use of Modafinil as A Performance-enhancing Drug in the Context of Military Operationality. ( Lacroix, E; Pattyn, N; Van Cutsem, J; Van Puyvelde, M, 2022) |
| "In a study of acute sleep deprivation in healthy male volunteers randomized to double-blind treatment with lisdexamfetamine dimesylate (20, 50, or 70 mg), placebo control, or an active control (armodafinil 250 mg), Maintenance of Wakefulness Test data were compared using a generalized estimating equation analysis to eliminate the need for unequivocal sleep latency imputation." | 2.79 | A generalized estimating equation approach to analysis of maintenance of wakefulness testing in a study of lisdexamfetamine dimesylate, armodafinil, and placebo in sleep-deprived adults. ( Donnelly, P; Ferreira-Cornwell, MC; Freeman, J; Gao, J; Gasior, M; Roth, T; Zammit, G, 2014) |
| "These effects of sleep deprivation are counteracted by the adenosine receptor antagonist caffeine, implying involvement of the adenosine neuromodulator/receptor system." | 2.77 | Polymorphisms of ADORA2A modulate psychomotor vigilance and the effects of caffeine on neurobehavioural performance and sleep EEG after sleep deprivation. ( Bachmann, V; Bodenmann, S; Deckert, J; Freitag, C; Hohoff, C; Landolt, HP; Rétey, JV, 2012) |
| "After placebo, sleep deprivation was associated with enhancements in delta and theta and reductions in alpha and beta activity." | 2.76 | Effect of a novel histamine subtype-3 receptor inverse agonist and modafinil on EEG power spectra during sleep deprivation and recovery sleep in male volunteers. ( Boyle, J; Calder, N; Cerchio, K; Dijk, DJ; Gottesdiener, K; Hargreaves, R; Iannone, R; James, LM; Murphy, MG; Palcza, J; Renger, JJ, 2011) |
| "Treatment with modafinil significantly attenuated the performance decrements seen for several parameters including cognitive-psychomotor speed, visual attention and reaction times both with progressive hours awake and when working at adverse circadian phases." | 2.75 | Effect of modafinil on impairments in neurobehavioral performance and learning associated with extended wakefulness and circadian misalignment. ( Aeschbach, D; Czeisler, CA; Grady, S; Wright, KP, 2010) |
| "Modafinil treatment reduced lane deviation but had less effect on speed deviation, off-road incidents and reaction time to a concurrent task." | 2.73 | Effects of modafinil on simulator driving and self-assessment of driving following sleep deprivation. ( Broadbear, JH; Gurtman, CG; Redman, JR, 2008) |
| "Following 47 h of sleep deprivation, the study examined the effect of three stimulant medications (modafinil 400 mg, dextroamphetamine 20 mg, caffeine 600 mg) or placebo on the ability of 54 healthy participants to discriminate and label simple emotional expressions versus complex affect blends (created by morphing photographs of two different affective facial expressions)." | 2.73 | The effects of modafinil, caffeine, and dextroamphetamine on judgments of simple versus complex emotional expressions following sleep deprivation. ( Grugle, NL; Huck, NO; Kendall, AP; Killgore, WD; McBride, SA, 2008) |
| "Armodafinil doses were well tolerated, with the most common adverse events including abdominal pain, nausea, and headache." | 2.72 | Pharmacodynamic effects on alertness of single doses of armodafinil in healthy subjects during a nocturnal period of acute sleep loss. ( Arora, S; Darwish, M; Dinges, DF; Niebler, GE, 2006) |
| "Modafinil is a selective wakefulness-promoting agent that has been shown to enhance cognitive performance under conditions of sleep deprivation but which has equivocal effects in normal young volunteers." | 2.71 | The cognitive-enhancing properties of modafinil are limited in non-sleep-deprived middle-aged volunteers. ( File, SE; Fleck, NL; Randall, DC; Shneerson, JM, 2004) |
| "Modafinil was without effect in several tests of reaction time and attention, but the 200-mg group was faster at simple color naming of dots and performed better than placebo in the Rapid Visual Information Processing test of sustained attention." | 2.71 | Does modafinil enhance cognitive performance in young volunteers who are not sleep-deprived? ( Bharania, P; Elsabagh, SM; File, SE; Hartley, DE; Randall, DC; Shneerson, JM; Viswanath, A, 2005) |
| "We studied the circadian rhythm of rectal temperature (CRTre) during 62 h of SD alone or with three dosage levels of modafinil." | 2.70 | Circadian rhythm of rectal temperature during sleep deprivation with modafinil. ( Besnard, Y; Bittel, J; Guinet, A; Lallement, G; Launay, JC; Savourey, G, 2002) |
| "The occurrence of chronic sleep deprivation in the population is commonplace." | 2.43 | Sleep deprivation. ( Kaplan, J; Malik, SW, 2005) |
| "Modafinil also impairs post-sleep deprivation recovery sleep, but from the few studies available addressing this issue, it is unclear whether these sleep impairments translate into post-sleep performance impairments." | 2.43 | Effects of modafinil on cognitive performance and alertness during sleep deprivation. ( Wesensten, NJ, 2006) |
| "Armodafinil is a wake-promoting agent against sleep deprivation related disorders." | 1.62 | Application of armodafinil-loaded microneedle patches against the negative influence induced by sleep deprivation. ( Du, L; Jin, Y; Li, Q; Ou, G; Wang, L; Yu, X; Zhang, S; Zhang, Y; Zhu, L; Zhu, S; Zhuang, X, 2021) |
| "In the PLACEBO condition, the sleep deprivation induced an increase and a decrease in posterior delta (2-4 Hz) and alpha (8-13 Hz) source activities, respectively." | 1.51 | Sleep deprivation and Modafinil affect cortical sources of resting state electroencephalographic rhythms in healthy young adults. ( Babiloni, C; Bartrés-Faz, D; Blin, O; Bordet, R; Bourriez, JL; Casse-Perrot, C; Chauveau, N; Del Percio, C; Deplanque, D; Derambure, P; Dukart, J; Ferri, R; Lanteaume, L; Lizio, R; Méligne, D; Noce, G; Pascarelli, MT; Payoux, P; Richardson, JC; Thalamas, C, 2019) |
| "The consequences of chronic insufficient sleep for health remain uncertain." | 1.46 | Decreased alertness due to sleep loss increases pain sensitivity in mice. ( Alexandre, C; Ferreira, A; Latremoliere, A; Miracca, G; Scammell, TE; Woolf, CJ; Yamamoto, M, 2017) |
| "Caffeine treatment prevented the SD induced down-regulation of synaptophysin and synapsin I proteins with no change in PSD-95 protein in hippocampus." | 1.42 | Caffeine and modafinil given during 48 h sleep deprivation modulate object recognition memory and synaptic proteins in the hippocampus of the rat. ( Kauser, H; Kumari, P; Panjwani, U; Ray, K; Sahu, S; Wadhwa, M, 2015) |
| "Sleep deprivation is known to be a stressor, affecting multiple body functions such as the cognition." | 1.39 | Modafinil ameliorates cognitive deficits induced by maternal separation and sleep deprivation. ( Alvarenga, T; Andersen, ML; Garcia, VA; Hirotsu, C; Kapczinski, F; Matos, G; Pires, GN; Schröder, N; Tufik, S, 2013) |
| "Caffeine treatment during SD, significantly increased early proliferative and post-mitotic stages of doublecortin (DCX) positive cells while modafinil treatment during SD, increased intermediate and post-mitotic stages of DCX positive cells compared to SD+Vehicle group." | 1.39 | Caffeine and modafinil promote adult neuronal cell proliferation during 48 h of total sleep deprivation in rat dentate gyrus. ( Kauser, H; Kishore, K; Kumar, S; Panjwani, U; Ray, K; Sahu, S, 2013) |
| "Modafinil is a wake-promoting drug and has been approved for the treatment of excessive daytime sleepiness in narcolepsy and obstructive sleep apnea." | 1.39 | Differential effects of modafinil on memory in naïve and memory-impaired rats. ( Busato, SB; D'avila Portal, BC; Garcia, VA; Piazza, FC; Schröder, N; Souza de Freitas, B, 2013) |
| "Previous work showed that sleep deprivation (SD) impairs hippocampal-dependent cognitive function and synaptic plasticity, and a novel wake-promoting agent modafinil prevents SD-induced memory impairment in rat." | 1.37 | Modafinil treatment prevents REM sleep deprivation-induced brain function impairment by increasing MMP-9 expression. ( He, B; Peng, H; Zhao, Y; Zhao, Z; Zhou, H, 2011) |
| "We showed that a 10-hr total sleep deprivation impaired the CSD task but not the SSD one." | 1.37 | Differential effects of total sleep deprivation on contextual and spatial memory: modulatory effects of modafinil. ( Beracochea, D; Chauveau, F; Corio, M; Coutan, M; Krazem, A; Liscia, P; Pierard, C, 2011) |
| "Wakefulness was maintained by "gentle sleep deprivation" method (GSD) or by administration of the wakefulness-promoting drug modafinil (MOD) (200 mg/kg i." | 1.36 | Metabolic response of the cerebral cortex following gentle sleep deprivation and modafinil administration. ( Borbély, AA; Kopp, C; Magistretti, PJ; Morgenthaler, F; Petit, JM; Tobler, I, 2010) |
| "The effects of sleep deprivation are a burden in our 24-h society." | 1.35 | Efficacy of caffeine and modafinil in counteracting sleep deprivation in the marmoset monkey. ( Jongsma, MJ; Olivier, B; Philippens, IH; van Vliet, SA; Vanwersch, RA, 2008) |
| "For this purpose, an original sleep deprivation apparatus was developed and validated with continuous electroencephalography recording." | 1.34 | Modafinil restores memory performance and neural activity impaired by sleep deprivation in mice. ( Béracochéa, D; Chauveau, F; Drouet, I; Jouanin, JC; Lafon, T; Liscia, P; Mons, N; Philippin, JN; Piérard, C; Serra, A; Van Beers, P, 2007) |
| "Modafinil is a wakefulness-promoting substance whose profile differs from that of the classical psychostimulants." | 1.31 | Comparison of the effects of modafinil and sleep deprivation on sleep and cortical EEG spectra in mice. ( Borbély, AA; Kopp, C; Magistretti, P; Petit, JM; Tobler, I, 2002) |
| "Modafinil is a newly discovered waking substance now being used in the treatment of hypersomnia and narcolepsy." | 1.31 | Effects of amphetamine and modafinil on the sleep/wake cycle during experimental hypersomnia induced by sleep deprivation in the cat. ( Frydman, A; Gervasoni, D; Hou, Y; Jouvet, M; Lin, JS; Rambert, F; Vanni-Mercier, G, 2000) |
| "Modafinil treatment did not significantly modify the brain cortex content of any of the amino acids tested." | 1.29 | Paradoxical sleep deprivation increases the content of glutamate and glutamine in rat cerebral cortex. ( Bettendorff, L; Margineanu, I; Sallanon-Moulin, M; Schoffeniels, E; Touret, M; Wins, P, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (7.06) | 18.2507 |
| 2000's | 37 (43.53) | 29.6817 |
| 2010's | 33 (38.82) | 24.3611 |
| 2020's | 9 (10.59) | 2.80 |
| Authors | Studies |
|---|---|
| Van Puyvelde, M | 1 |
| Van Cutsem, J | 1 |
| Lacroix, E | 1 |
| Pattyn, N | 1 |
| Zhu, L | 1 |
| Zhang, S | 1 |
| Yu, X | 2 |
| Zhu, S | 1 |
| Ou, G | 1 |
| Li, Q | 3 |
| Zhang, Y | 1 |
| Wang, L | 2 |
| Zhuang, X | 1 |
| Du, L | 1 |
| Jin, Y | 1 |
| Xu, L | 1 |
| Yang, X | 1 |
| Peng, Z | 1 |
| Song, T | 1 |
| Dai, C | 1 |
| Xu, M | 1 |
| Shao, Y | 1 |
| Lv, J | 1 |
| Wingelaar-Jagt, YQ | 2 |
| Bottenheft, C | 2 |
| Riedel, WJ | 2 |
| Ramaekers, JG | 2 |
| Puech, C | 1 |
| Badran, M | 1 |
| Barrow, MB | 1 |
| Runion, AR | 1 |
| Gozal, D | 1 |
| Sauvet, F | 1 |
| Erblang, M | 1 |
| Gomez-Merino, D | 1 |
| Rabat, A | 1 |
| Guillard, M | 1 |
| Dubourdieu, D | 1 |
| Lefloch, H | 1 |
| Drogou, C | 1 |
| Van Beers, P | 3 |
| Bougard, C | 1 |
| Bourrrilhon, C | 1 |
| Arnal, P | 1 |
| Rein, W | 1 |
| Mouthon, F | 1 |
| Brunner-Ferber, F | 1 |
| Leger, D | 1 |
| Dauvilliers, Y | 1 |
| Chennaoui, M | 1 |
| Charvériat, M | 1 |
| Li, YD | 1 |
| Ge, J | 1 |
| Luo, YJ | 1 |
| Xu, W | 1 |
| Wang, J | 1 |
| Lazarus, M | 1 |
| Hong, ZY | 1 |
| Qu, WM | 1 |
| Huang, ZL | 1 |
| Caldwell, JL | 2 |
| Schroeder, VM | 1 |
| Kunkle, CL | 1 |
| Stephenson, HG | 1 |
| Sholtes, D | 1 |
| Kravitz, HM | 1 |
| Deka, A | 1 |
| Westrick, J | 1 |
| Fogg, LF | 1 |
| Gottlieb, M | 1 |
| Ehlert, AM | 1 |
| Wilson, PB | 1 |
| Alexandre, C | 1 |
| Latremoliere, A | 1 |
| Ferreira, A | 1 |
| Miracca, G | 1 |
| Yamamoto, M | 1 |
| Scammell, TE | 1 |
| Woolf, CJ | 1 |
| Canellas-Dols, F | 1 |
| Delgado, C | 1 |
| Arango-Lopez, C | 1 |
| Peraita-Adrados, R | 1 |
| Ma, Y | 1 |
| Harding, EC | 1 |
| Yustos, R | 1 |
| Vyssotski, AL | 1 |
| Franks, NP | 1 |
| Wisden, W | 1 |
| Cao, Y | 1 |
| Liu, L | 1 |
| Wu, H | 1 |
| Huang, F | 1 |
| Wang, C | 1 |
| Lan, Y | 1 |
| Zheng, F | 1 |
| Xing, F | 1 |
| Zhou, Q | 1 |
| Shi, H | 1 |
| Zhang, B | 1 |
| Wang, Z | 1 |
| Wu, X | 1 |
| Del Percio, C | 1 |
| Derambure, P | 1 |
| Noce, G | 1 |
| Lizio, R | 1 |
| Bartrés-Faz, D | 1 |
| Blin, O | 1 |
| Payoux, P | 1 |
| Deplanque, D | 1 |
| Méligne, D | 1 |
| Chauveau, N | 1 |
| Bourriez, JL | 1 |
| Casse-Perrot, C | 1 |
| Lanteaume, L | 1 |
| Thalamas, C | 1 |
| Dukart, J | 1 |
| Ferri, R | 1 |
| Pascarelli, MT | 1 |
| Richardson, JC | 1 |
| Bordet, R | 1 |
| Babiloni, C | 1 |
| Garcia, VA | 2 |
| Hirotsu, C | 1 |
| Matos, G | 1 |
| Alvarenga, T | 1 |
| Pires, GN | 1 |
| Kapczinski, F | 1 |
| Schröder, N | 2 |
| Tufik, S | 3 |
| Andersen, ML | 2 |
| Conrado, DJ | 1 |
| Bewernitz, M | 1 |
| Ding, M | 1 |
| Cibula, J | 1 |
| Seubert, C | 1 |
| Sy, SK | 1 |
| Eisenschenk, S | 1 |
| Derendorf, H | 1 |
| Sahu, S | 3 |
| Kauser, H | 2 |
| Ray, K | 3 |
| Kishore, K | 1 |
| Kumar, S | 2 |
| Panjwani, U | 3 |
| Souza de Freitas, B | 1 |
| Busato, SB | 1 |
| D'avila Portal, BC | 1 |
| Piazza, FC | 1 |
| Barsevick, AM | 1 |
| Irwin, MR | 1 |
| Hinds, P | 1 |
| Miller, A | 1 |
| Berger, A | 1 |
| Jacobsen, P | 1 |
| Ancoli-Israel, S | 1 |
| Reeve, BB | 1 |
| Mustian, K | 1 |
| O'Mara, A | 1 |
| Lai, JS | 1 |
| Fisch, M | 1 |
| Cella, D | 1 |
| Gasior, M | 2 |
| Freeman, J | 2 |
| Zammit, G | 2 |
| Donnelly, P | 2 |
| Gao, J | 2 |
| Ferreira-Cornwell, MC | 2 |
| Roth, T | 2 |
| Loomis, S | 1 |
| McCarthy, A | 1 |
| Baxter, C | 1 |
| Kellett, DO | 1 |
| Edgar, DM | 1 |
| Tricklebank, M | 1 |
| Gilmour, G | 1 |
| Wadhwa, M | 1 |
| Kumari, P | 1 |
| Flindall, I | 1 |
| Leff, DR | 1 |
| Goodship, J | 1 |
| Sugden, C | 2 |
| Darzi, A | 2 |
| Parker, RS | 1 |
| Parker, P | 1 |
| Killgore, WD | 8 |
| Rupp, TL | 1 |
| Grugle, NL | 6 |
| Reichardt, RM | 2 |
| Lipizzi, EL | 1 |
| Balkin, TJ | 10 |
| Ramsey, CS | 1 |
| Werchan, PM | 1 |
| Isdahl, WM | 1 |
| Fischer, J | 1 |
| Gibbons, JA | 1 |
| Killgore, DB | 5 |
| Leavitt, BP | 1 |
| Watlington, GI | 1 |
| McNair, S | 1 |
| Muckle, AE | 1 |
| Bodenmann, S | 3 |
| Xu, S | 1 |
| Luhmann, UF | 1 |
| Arand, M | 1 |
| Berger, W | 1 |
| Jung, HH | 1 |
| Landolt, HP | 3 |
| Gurtman, CG | 1 |
| Broadbear, JH | 1 |
| Redman, JR | 1 |
| Kahn-Greene, ET | 1 |
| Beck, J | 1 |
| Hemmeter, U | 1 |
| Brand, S | 1 |
| Muheim, F | 1 |
| Hatzinger, M | 1 |
| Holsboer-Trachsler, E | 1 |
| Grady, S | 1 |
| Aeschbach, D | 1 |
| Wright, KP | 1 |
| Czeisler, CA | 1 |
| Buxton, OM | 1 |
| Pavlova, M | 1 |
| Reid, EW | 1 |
| Wang, W | 1 |
| Simonson, DC | 1 |
| Adler, GK | 1 |
| Petit, JM | 2 |
| Tobler, I | 2 |
| Kopp, C | 2 |
| Morgenthaler, F | 1 |
| Borbély, AA | 2 |
| Magistretti, PJ | 1 |
| Moreira, KM | 1 |
| Ferreira, TL | 1 |
| Hipolide, DC | 1 |
| Fornari, RV | 1 |
| Oliveira, MG | 1 |
| Liu, YP | 2 |
| Tung, CS | 2 |
| Lin, YL | 1 |
| Chuang, CH | 2 |
| Pierard, C | 2 |
| Liscia, P | 2 |
| Chauveau, F | 2 |
| Coutan, M | 1 |
| Corio, M | 1 |
| Krazem, A | 1 |
| Beracochea, D | 2 |
| Lo, SM | 1 |
| Ku, YC | 1 |
| James, LM | 1 |
| Iannone, R | 1 |
| Palcza, J | 1 |
| Renger, JJ | 1 |
| Calder, N | 1 |
| Cerchio, K | 1 |
| Gottesdiener, K | 1 |
| Hargreaves, R | 1 |
| Murphy, MG | 1 |
| Boyle, J | 1 |
| Dijk, DJ | 1 |
| Arias-Carrión, O | 1 |
| Palomero-Rivero, M | 1 |
| Millán-Aldaco, D | 1 |
| Haro, R | 1 |
| Drucker-Colín, R | 1 |
| Murillo-Rodríguez, E | 1 |
| Hohoff, C | 1 |
| Freitag, C | 1 |
| Deckert, J | 1 |
| Rétey, JV | 1 |
| Bachmann, V | 1 |
| Housden, CR | 1 |
| Aggarwal, R | 1 |
| Sahakian, BJ | 1 |
| He, B | 1 |
| Peng, H | 1 |
| Zhao, Y | 1 |
| Zhou, H | 1 |
| Zhao, Z | 1 |
| Chatterjee, A | 1 |
| Ghosh, S | 1 |
| Thakur, L | 1 |
| Anand, JP | 1 |
| Magistretti, P | 1 |
| Launay, JC | 1 |
| Savourey, G | 1 |
| Guinet, A | 1 |
| Lallement, G | 1 |
| Besnard, Y | 1 |
| Bittel, J | 1 |
| McLellan, TM | 1 |
| Ducharme, MB | 1 |
| Canini, F | 1 |
| Moroz, D | 1 |
| Bell, DG | 1 |
| Baranski, JV | 2 |
| Gil, V | 1 |
| Buguet, A | 1 |
| Radomski, MW | 1 |
| Ponomarenko, AA | 1 |
| Lin, JS | 3 |
| Selbach, O | 1 |
| Haas, HL | 1 |
| Li, YF | 1 |
| Zhan, H | 1 |
| Xin, YM | 1 |
| Tang, GX | 1 |
| Wei, SH | 1 |
| Li, T | 1 |
| Randall, DC | 2 |
| Fleck, NL | 1 |
| Shneerson, JM | 2 |
| File, SE | 2 |
| Wesensten, NJ | 5 |
| Belenky, G | 2 |
| Thorne, DR | 2 |
| Kautz, MA | 2 |
| Caldwell, JA | 1 |
| Smith, JK | 1 |
| Brown, DL | 1 |
| Viswanath, A | 1 |
| Bharania, P | 1 |
| Elsabagh, SM | 1 |
| Hartley, DE | 1 |
| Russo, M | 1 |
| Maher, C | 1 |
| Campbell, W | 1 |
| Malik, SW | 1 |
| Kaplan, J | 1 |
| Giles, J | 1 |
| Bonnet, MH | 1 |
| Dinges, DF | 2 |
| Roehrs, T | 1 |
| Rogers, NL | 1 |
| Even, C | 1 |
| Thuile, J | 1 |
| Santos, J | 1 |
| Bourgin, P | 1 |
| Arora, S | 1 |
| Darwish, M | 1 |
| Niebler, GE | 1 |
| McBride, SA | 2 |
| Thomas, RJ | 1 |
| Kwong, K | 1 |
| Eliyahu, U | 1 |
| Berlin, S | 1 |
| Hadad, E | 1 |
| Heled, Y | 1 |
| Moran, DS | 1 |
| Philippin, JN | 1 |
| Mons, N | 1 |
| Lafon, T | 1 |
| Drouet, I | 1 |
| Serra, A | 1 |
| Jouanin, JC | 1 |
| van Vliet, SA | 1 |
| Jongsma, MJ | 1 |
| Vanwersch, RA | 1 |
| Olivier, B | 1 |
| Philippens, IH | 1 |
| Tononi, G | 1 |
| Cirelli, C | 1 |
| Rao, Y | 1 |
| Liu, ZW | 1 |
| Borok, E | 1 |
| Rabenstein, RL | 1 |
| Shanabrough, M | 1 |
| Lu, M | 1 |
| Picciotto, MR | 1 |
| Horvath, TL | 1 |
| Gao, XB | 1 |
| Soya, A | 1 |
| Song, YH | 1 |
| Kodama, T | 1 |
| Honda, Y | 1 |
| Fujiki, N | 1 |
| Nishino, S | 1 |
| Martins, RC | 1 |
| Shih, MC | 1 |
| Plante, DT | 1 |
| Huck, NO | 1 |
| Kendall, AP | 1 |
| Lagarde, D | 1 |
| Batejat, D | 1 |
| Sarafian, D | 1 |
| Pradella, S | 1 |
| Bettendorff, L | 1 |
| Sallanon-Moulin, M | 1 |
| Touret, M | 1 |
| Wins, P | 1 |
| Margineanu, I | 1 |
| Schoffeniels, E | 1 |
| Pigeau, RA | 1 |
| Brun, J | 1 |
| Chamba, G | 1 |
| Khalfallah, Y | 1 |
| Girard, P | 1 |
| Boissy, I | 1 |
| Bastuji, H | 1 |
| Sassolas, G | 1 |
| Claustrat, B | 1 |
| Batéjat, DM | 1 |
| Lagarde, DP | 1 |
| Gervasoni, D | 1 |
| Hou, Y | 1 |
| Vanni-Mercier, G | 1 |
| Rambert, F | 1 |
| Frydman, A | 1 |
| Jouvet, M | 1 |
| Hou, YP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Therapeutic Impact of THN102 on Attention, Wakefulness and Cognitive Performance During Total Sleep Deprivation in Healthy Subjects[NCT03182413] | Phase 1 | 20 participants (Actual) | Interventional | 2015-09-30 | Completed | ||
| Feasibility Study of a Hypnosis Intervention and a Cognitive Behavioral Therapy Intervention to Reduce Fatigue in Patients Undergoing Chemotherapy for Metastatic Colorectal Cancer[NCT04999306] | 60 participants (Anticipated) | Interventional | 2023-05-17 | Recruiting | |||
| Effect of Resistance Training Variable Manipulation (Intensity and Volume) on Body Composition, Fatigability and Functional Capacity in Postmenopausal Breast Cancer Survivors.[NCT03644329] | 80 participants (Anticipated) | Interventional | 2018-05-13 | Recruiting | |||
| A Head-to-Head Comparison of the 2B-Alert Caffeine Optimization Algorithm Versus Standard Caffeine Dosing on Performance During Sleep Deprivation (2B-2)[NCT05588934] | 180 participants (Anticipated) | Interventional | 2023-02-28 | Not yet recruiting | |||
| Impact of Sleep Restriction on Cardiometabolic Risk Factors in Pre vs Postmenopausal Women[NCT02835261] | 54 participants (Actual) | Interventional | 2016-09-01 | Completed | |||
| Sleep Restriction, Impaired Glucose Metabolism, and Performance: The Effects of Modafinil to Counteract the Adverse Metabolic Consequences of Sleep Restriction[NCT00895570] | 20 participants (Actual) | Interventional | 2005-01-31 | Completed | |||
| The SLuMBER Study: The Sleep Lengthening and Metabolic Health, Body Composition, Energy Balance and Cardiovascular Risk Study[NCT02787577] | 43 participants (Actual) | Interventional | 2016-04-30 | Completed | |||
| Sleep for Health: A Randomized Clinical Trial Examining the Effects of Cognitive Behavioral Therapy for Insomnia on Diabetes Risk[NCT06067139] | 300 participants (Anticipated) | Interventional | 2023-08-01 | Recruiting | |||
| Sleep Duration and Glycemic Control in Adolescents With Type 2 Diabetes Mellitus[NCT04213547] | 31 participants (Actual) | Interventional | 2020-09-16 | Active, not recruiting | |||
| The Effect of Caffeine on the Narcoleptic Patients Randomized Controlled Clinical Trial[NCT02832336] | Phase 1/Phase 2 | 16 participants (Actual) | Interventional | 2016-10-01 | Completed | ||
| Neurochemical Modulation Cognitive Performance and Subjective Wellbeing In Healthy Controls[NCT02051153] | 64 participants (Actual) | Interventional | 2009-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for modafinil and Inadequate Sleep
| Article | Year |
|---|---|
A State-of-the-Art Review on the Use of Modafinil as A Performance-enhancing Drug in the Context of Military Operationality.
Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Cognition; Double-Blind Method; Humans; Mil | 2022 |
Optimising sleep and performance during night float: A systematic review of evidence and implications for graduate medical education trainees.
Topics: Adaptation, Physiological; Attention; Caffeine; Education, Medical, Graduate; Energy Drinks; Fatigue | 2021 |
Stimulant Use as a Fatigue Countermeasure in Aviation.
Topics: Aerospace Medicine; Aviation; Central Nervous System Stimulants; Fatigue; Humans; Modafinil; Sleep D | 2021 |
The impact of sleep deprivation in military surgical teams: a systematic review.
Topics: Benzhydryl Compounds; Clinical Competence; Cognition; Fatigue; Health Personnel; Humans; Military Me | 2017 |
Sleep deprivation.
Topics: Benzhydryl Compounds; Caffeine; Disorders of Excessive Somnolence; Humans; Modafinil; Primary Health | 2005 |
The use of stimulants to modify performance during sleep loss: a review by the sleep deprivation and Stimulant Task Force of the American Academy of Sleep Medicine.
Topics: Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Humans; Methamphetamine; Modafini | 2005 |
Effects of modafinil on cognitive performance and alertness during sleep deprivation.
Topics: Arousal; Benzhydryl Compounds; Central Nervous System Stimulants; Cognition; Dose-Response Relations | 2006 |
34 trials available for modafinil and Inadequate Sleep
| Article | Year |
|---|---|
Modafinil ameliorates the decline in pronunciation-related working memory caused by 36-h acute total sleep deprivation: An ERP study.
Topics: Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Humans; Male; Memory, Short-Term; | 2022 |
Effects of modafinil and caffeine on night-time vigilance of air force crewmembers: A randomized controlled trial.
Topics: Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Fatigue; Hum | 2023 |
Effects of modafinil and caffeine on night-time vigilance of air force crewmembers: A randomized controlled trial.
Topics: Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Fatigue; Hum | 2023 |
Effects of modafinil and caffeine on night-time vigilance of air force crewmembers: A randomized controlled trial.
Topics: Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Fatigue; Hum | 2023 |
Effects of modafinil and caffeine on night-time vigilance of air force crewmembers: A randomized controlled trial.
Topics: Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Fatigue; Hum | 2023 |
Efficacy of THN102 (a combination of modafinil and flecainide) on vigilance and cognition during 40-hour total sleep deprivation in healthy subjects: Glial connexins as a therapeutic target.
Topics: Adult; Arousal; Cognition; Connexins; Cross-Over Studies; Drug Combinations; Flecainide; Healthy Vol | 2019 |
Differential effects of modafinil on performance of low-performing and high-performing individuals during total sleep deprivation.
Topics: Adult; Double-Blind Method; Humans; Male; Modafinil; Placebos; Psychomotor Performance; Reaction Tim | 2020 |
Electroencephalogram effects of armodafinil: comparison with behavioral alertness.
Topics: Adult; Behavior; Benzhydryl Compounds; Cross-Over Studies; Double-Blind Method; Electroencephalograp | 2013 |
Maintenance of wakefulness with lisdexamfetamine dimesylate, compared with placebo and armodafinil in healthy adult males undergoing acute sleep loss.
Topics: Administration, Oral; Adult; Benzhydryl Compounds; Dextroamphetamine; Double-Blind Method; Health St | 2014 |
A generalized estimating equation approach to analysis of maintenance of wakefulness testing in a study of lisdexamfetamine dimesylate, armodafinil, and placebo in sleep-deprived adults.
Topics: Adolescent; Adult; Benzhydryl Compounds; Central Nervous System Stimulants; Double-Blind Method; Hea | 2014 |
Structured cues or modafinil for fatigue amelioration in clinicians? A double-blind, randomized controlled trial of critical clinical information recall in fatigued clinicians.
Topics: Adolescent; Adult; Benzhydryl Compounds; Cues; Double-Blind Method; Drug Administration Schedule; Fa | 2016 |
Effects of dextroamphetamine, caffeine and modafinil on psychomotor vigilance test performance after 44 h of continuous wakefulness.
Topics: Adolescent; Adult; Arousal; Attention; Benzhydryl Compounds; Caffeine; Central Nervous System Stimul | 2008 |
Restoration of risk-propensity during sleep deprivation: caffeine, dextroamphetamine, and modafinil.
Topics: Adult; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cognition; Decision Making | 2008 |
Pharmacogenetics of modafinil after sleep loss: catechol-O-methyltransferase genotype modulates waking functions but not recovery sleep.
Topics: Benzhydryl Compounds; Catechol O-Methyltransferase; Cross-Over Studies; Double-Blind Method; Genotyp | 2009 |
Effects of modafinil on simulator driving and self-assessment of driving following sleep deprivation.
Topics: Administration, Oral; Adult; Attention; Automobile Driving; Benzhydryl Compounds; Central Nervous Sy | 2008 |
Sustaining executive functions during sleep deprivation: A comparison of caffeine, dextroamphetamine, and modafinil.
Topics: Adolescent; Adult; Arousal; Attention; Benzhydryl Compounds; Caffeine; Central Nervous System Stimul | 2009 |
Modafinil reduces microsleep during partial sleep deprivation in depressed patients.
Topics: Adult; Benzhydryl Compounds; Central Nervous System Stimulants; Depressive Disorder, Major; Double-B | 2010 |
Odor identification ability predicts executive function deficits following sleep deprivation.
Topics: Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Dextroamphetamine; Executive Func | 2010 |
Effect of modafinil on impairments in neurobehavioral performance and learning associated with extended wakefulness and circadian misalignment.
Topics: Adult; Analysis of Variance; Benzhydryl Compounds; Body Temperature; Cognition Disorders; Double-Bli | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Sleep restriction for 1 week reduces insulin sensitivity in healthy men.
Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent | 2010 |
Effects of modafinil on the sleep EEG depend on Val158Met genotype of COMT.
Topics: Alleles; Benzhydryl Compounds; Catechol O-Methyltransferase; Central Nervous System Stimulants; Cros | 2010 |
Effect of a novel histamine subtype-3 receptor inverse agonist and modafinil on EEG power spectra during sleep deprivation and recovery sleep in male volunteers.
Topics: Adolescent; Adult; Benzhydryl Compounds; Cross-Over Studies; Dopamine Agents; Dose-Response Relation | 2011 |
Polymorphisms of ADORA2A modulate psychomotor vigilance and the effects of caffeine on neurobehavioural performance and sleep EEG after sleep deprivation.
Topics: Adult; Aged; Attention; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cross-Ove | 2012 |
Effect of pharmacological enhancement on the cognitive and clinical psychomotor performance of sleep-deprived doctors: a randomized controlled trial.
Topics: Adult; Analysis of Variance; Benzhydryl Compounds; Central Nervous System Stimulants; Cognition; Com | 2012 |
Circadian rhythm of rectal temperature during sleep deprivation with modafinil.
Topics: Adult; Benzhydryl Compounds; Body Temperature; Central Nervous System Stimulants; Circadian Rhythm; | 2002 |
Effect of modafinil on core temperature during sustained wakefulness and exercise in a warm environment.
Topics: Adult; Benzhydryl Compounds; Body Temperature; Central Nervous System Stimulants; Dose-Response Rela | 2002 |
The cognitive-enhancing properties of modafinil are limited in non-sleep-deprived middle-aged volunteers.
Topics: Aged; Analysis of Variance; Benzhydryl Compounds; Cognition; Dose-Response Relationship, Drug; Doubl | 2004 |
Does modafinil enhance cognitive performance in young volunteers who are not sleep-deprived?
Topics: Adult; Benzhydryl Compounds; Cognition; Double-Blind Method; Female; Humans; Male; Modafinil; Neurop | 2005 |
Pharmacodynamic effects on alertness of single doses of armodafinil in healthy subjects during a nocturnal period of acute sleep loss.
Topics: Adolescent; Adult; Benzhydryl Compounds; Central Nervous System Stimulants; Double-Blind Method; Hum | 2006 |
The effects of caffeine, dextroamphetamine, and modafinil on humor appreciation during sleep deprivation.
Topics: Adolescent; Adult; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cognition; Dex | 2006 |
Modafinil activates cortical and subcortical sites in the sleep-deprived state.
Topics: Adult; Arousal; Attention; Benzhydryl Compounds; Brain; Brain Mapping; Central Nervous System Stimul | 2006 |
The effects of modafinil, caffeine, and dextroamphetamine on judgments of simple versus complex emotional expressions following sleep deprivation.
Topics: Adolescent; Adult; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cognition; Dex | 2008 |
Interest of modafinil, a new psychostimulant, during a sixty-hour sleep deprivation experiment.
Topics: Adult; Benzhydryl Compounds; Central Nervous System Stimulants; Electroencephalography; Humans; Male | 1995 |
Self-monitoring cognitive performance during sleep deprivation: effects of modafinil, d-amphetamine and placebo.
Topics: Adult; Benzhydryl Compounds; Central Nervous System Stimulants; Cognition; Dextroamphetamine; Double | 1997 |
Effect of modafinil on plasma melatonin, cortisol and growth hormone rhythms, rectal temperature and performance in healthy subjects during a 36 h sleep deprivation.
Topics: Adult; Benzhydryl Compounds; Body Temperature; Central Nervous System Stimulants; Health Status; Hum | 1998 |
Naps and modafinil as countermeasures for the effects of sleep deprivation on cognitive performance.
Topics: Adult; Benzhydryl Compounds; Central Nervous System Stimulants; Circadian Rhythm; Cognition; Double- | 1999 |
Maintaining alertness and performance during sleep deprivation: modafinil versus caffeine.
Topics: Administration, Oral; Adolescent; Adult; Analysis of Variance; Benzhydryl Compounds; Body Temperatur | 2002 |
44 other studies available for modafinil and Inadequate Sleep
| Article | Year |
|---|---|
Application of armodafinil-loaded microneedle patches against the negative influence induced by sleep deprivation.
Topics: Administration, Cutaneous; Animals; Cognition; Drug Delivery Systems; Drug Monitoring; Mice; Microte | 2021 |
Solriamfetol improves chronic sleep fragmentation-induced increases in sleep propensity and ameliorates explicit memory in male mice.
Topics: Animals; Disorders of Excessive Somnolence; Male; Mice; Mice, Inbred C57BL; Modafinil; Sleep; Sleep | 2023 |
High cortical delta power correlates with aggravated allodynia by activating anterior cingulate cortex GABAergic neurons in neuropathic pain mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Cerebral Cortex; Cholinergic Antagonists; Cortical Synchroniz | 2020 |
Decreased alertness due to sleep loss increases pain sensitivity in mice.
Topics: Acute Disease; Analgesics; Animals; Behavior, Animal; Benzhydryl Compounds; Caffeine; Chronic Diseas | 2017 |
Narcolepsy-cataplexy and psychosis: a case study.
Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Benzhydryl Compound | 2017 |
Genetic lesioning of histamine neurons increases sleep-wake fragmentation and reveals their contribution to modafinil-induced wakefulness.
Topics: Animals; Electroencephalography; Genetic Vectors; Histamine; Homeostasis; Male; Mice; Mice, Inbred C | 2019 |
Modafinil protects hippocampal neurons by suppressing excessive autophagy and apoptosis in mice with sleep deprivation.
Topics: Animals; Apoptosis; Autophagy; Central Nervous System Stimulants; Hippocampus; Male; Mice; Mice, Inb | 2019 |
Sleep deprivation and Modafinil affect cortical sources of resting state electroencephalographic rhythms in healthy young adults.
Topics: Adult; Alpha Rhythm; Beta Rhythm; Brain Waves; Cerebral Cortex; Cross-Over Studies; Delta Rhythm; El | 2019 |
Modafinil ameliorates cognitive deficits induced by maternal separation and sleep deprivation.
Topics: Analysis of Variance; Animals; Anxiety, Separation; Benzhydryl Compounds; Central Nervous System Sti | 2013 |
Caffeine and modafinil promote adult neuronal cell proliferation during 48 h of total sleep deprivation in rat dentate gyrus.
Topics: Animals; Benzhydryl Compounds; Brain-Derived Neurotrophic Factor; Caffeine; Cell Count; Cell Prolife | 2013 |
Differential effects of modafinil on memory in naïve and memory-impaired rats.
Topics: Analysis of Variance; Animals; Animals, Newborn; Avoidance Learning; Benzhydryl Compounds; Disease M | 2013 |
Recommendations for high-priority research on cancer-related fatigue in children and adults.
Topics: Adult; Anxiety; Benzhydryl Compounds; Bupropion; Central Nervous System Stimulants; Child; Clinical | 2013 |
Recommendations for high-priority research on cancer-related fatigue in children and adults.
Topics: Adult; Anxiety; Benzhydryl Compounds; Bupropion; Central Nervous System Stimulants; Child; Clinical | 2013 |
Recommendations for high-priority research on cancer-related fatigue in children and adults.
Topics: Adult; Anxiety; Benzhydryl Compounds; Bupropion; Central Nervous System Stimulants; Child; Clinical | 2013 |
Recommendations for high-priority research on cancer-related fatigue in children and adults.
Topics: Adult; Anxiety; Benzhydryl Compounds; Bupropion; Central Nervous System Stimulants; Child; Clinical | 2013 |
Distinct pro-vigilant profile induced in rats by the mGluR5 potentiator LSN2814617.
Topics: Animals; Arousal; Benzhydryl Compounds; Biofeedback, Psychology; Caffeine; Central Nervous System St | 2015 |
Caffeine and modafinil given during 48 h sleep deprivation modulate object recognition memory and synaptic proteins in the hippocampus of the rat.
Topics: Animals; Benzhydryl Compounds; Caffeine; Disease Models, Animal; Disks Large Homolog 4 Protein; Drug | 2015 |
Acceleration tolerance at night with acute fatigue and stimulants.
Topics: Acceleration; Adaptation, Physiological; Adult; Aerospace Medicine; Amphetamine; Analysis of Varianc | 2008 |
Sex differences in cognitive estimation during sleep deprivation: effects of stimulant countermeasures.
Topics: Adenosine; Adult; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cognition; Cogn | 2008 |
Metabolic response of the cerebral cortex following gentle sleep deprivation and modafinil administration.
Topics: Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cerebral Cortex; Disease Models, A | 2010 |
Modafinil prevents inhibitory avoidance memory deficit induced by sleep deprivation in rats.
Topics: Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Benzhydryl Compounds; Disease M | 2010 |
Wake-promoting agent modafinil worsened attentional performance following REM sleep deprivation in a young-adult rat model of 5-choice serial reaction time task.
Topics: Age Factors; Animals; Attention; Benzhydryl Compounds; Central Nervous System Stimulants; Choice Beh | 2011 |
Differential effects of total sleep deprivation on contextual and spatial memory: modulatory effects of modafinil.
Topics: Animals; Behavior, Animal; Benzhydryl Compounds; Central Nervous System Stimulants; Corticosterone; | 2011 |
Tail-pinch stress and REM sleep deprivation differentially affect sensorimotor gating function in modafinil-treated rats.
Topics: Acoustic Stimulation; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Male; Modafi | 2011 |
Infusion of modafinil into anterior hypothalamus or pedunculopontine tegmental nucleus at different time-points enhances waking and blocks the expression of recovery sleep in rats after sleep deprivation.
Topics: Analysis of Variance; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Electroencep | 2011 |
Modafinil treatment prevents REM sleep deprivation-induced brain function impairment by increasing MMP-9 expression.
Topics: Analysis of Variance; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cognition; G | 2011 |
Modafinil improves event related potentials P300 and contingent negative variation after 24 h sleep deprivation.
Topics: Actigraphy; Adult; Benzhydryl Compounds; Body Weight; Central Nervous System Stimulants; Cognition; | 2012 |
Comparison of the effects of modafinil and sleep deprivation on sleep and cortical EEG spectra in mice.
Topics: Analysis of Variance; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Electroencep | 2002 |
Temporal pattern of hippocampal high-frequency oscillations during sleep after stimulant-evoked waking.
Topics: Amphetamine; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Dose-Response Relatio | 2003 |
[Effects of modafinil on visual and auditory reaction abilities and subjective fatigue level during 48 h sleep deprivation].
Topics: Adolescent; Adult; Attention; Auditory Perception; Benzhydryl Compounds; Central Nervous System Stim | 2003 |
Modafinil vs. caffeine: effects on fatigue during sleep deprivation.
Topics: Adolescent; Adult; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Dose-Response | 2004 |
Modafinil's effects on simulator performance and mood in pilots during 37 h without sleep.
Topics: Adult; Affect; Aviation; Benzhydryl Compounds; Central Nervous System Stimulants; Computer Simulatio | 2004 |
Cosmetic neurology: the controversy over enhancing movement, mentation, and mood.
Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Humans; Judgment; Military Medicine; Modafi | 2005 |
Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.
Topics: Adult; Arousal; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cognition; Dextro | 2005 |
Alertness drug arouses fears about 'lifestyle' misuse.
Topics: Alzheimer Disease; Animals; Attention; Benzhydryl Compounds; Clinical Trials as Topic; Cognition; Gl | 2005 |
Modafinil as an adjunctive treatment to sleep deprivation in depression.
Topics: Aged; Benzhydryl Compounds; Bipolar Disorder; Central Nervous System Stimulants; Depressive Disorder | 2005 |
Psychostimulants and military operations.
Topics: Adult; Benzhydryl Compounds; Central Nervous System Stimulants; Circadian Rhythm; Cognition; Dextroa | 2007 |
Modafinil restores memory performance and neural activity impaired by sleep deprivation in mice.
Topics: Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Electroencephalography; Genes, fos | 2007 |
Efficacy of caffeine and modafinil in counteracting sleep deprivation in the marmoset monkey.
Topics: Administration, Oral; Animals; Arousal; Attention; Benzhydryl Compounds; Callithrix; Central Nervous | 2008 |
Staying awake puts pressure on brain arousal systems.
Topics: Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cyclic AMP; Dopamine; Female; Hypo | 2007 |
Prolonged wakefulness induces experience-dependent synaptic plasticity in mouse hypocretin/orexin neurons.
Topics: Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cyclic AMP; Dopamine; Female; Hypo | 2007 |
CSF histamine levels in rats reflect the central histamine neurotransmission.
Topics: Amphetamine; Animals; Benzhydryl Compounds; Brain; Central Nervous System Stimulants; Circadian Rhyt | 2008 |
Effects of cocaine, methamphetamine and modafinil challenge on sleep rebound after paradoxical sleep deprivation in rats.
Topics: Analysis of Variance; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Mal | 2008 |
Treatment-emergent hypomania or mania with modafinil.
Topics: Adult; Antidepressive Agents; Benzhydryl Compounds; Bipolar Disorder; Central Nervous System Stimula | 2008 |
Paradoxical sleep deprivation increases the content of glutamate and glutamine in rat cerebral cortex.
Topics: Animals; Arousal; Benzhydryl Compounds; Central Nervous System Stimulants; Cerebral Cortex; gamma-Am | 1996 |
Effects of amphetamine and modafinil on the sleep/wake cycle during experimental hypersomnia induced by sleep deprivation in the cat.
Topics: Amphetamine; Animals; Benzhydryl Compounds; Cats; Central Nervous System Stimulants; Disorders of Ex | 2000 |
Effects of modafinil and amphetamine on sleep-wake cycle after sleep deprivation in cats.
Topics: Amphetamine; Animals; Benzhydryl Compounds; Cats; Central Nervous System Stimulants; Electroencephal | 1999 |