modafinil has been researched along with Hypoxia in 2 studies
Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the hypothesis that modafinil enhances resting ventilation as well as the stimulatory ventilatory responses to hypercapnia and hypoxia." | 3.83 | Disharmony between wake- and respiration-promoting activities: effects of modafinil on ventilatory control in rodents. ( Fukushi, I; Hasebe, Y; Okada, Y; Pokorski, M; Takeda, K; Tatsumi, K; Terada, J, 2016) |
| "OSA can induce excessive daytime sleepiness (EDS) and is associated with impaired cognition and anxiety." | 1.91 | Recovery Mimicking "Ideal" CPAP Adherence Does Not Improve Wakefulness or Cognition in Chronic Murine Models of OSA: Effect of Wake-Promoting Agents. ( Badran, M; Barrow, MB; Gozal, D; Puech, C; Runion, AR, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Badran, M | 1 |
| Puech, C | 1 |
| Barrow, MB | 1 |
| Runion, AR | 1 |
| Gozal, D | 1 |
| Terada, J | 1 |
| Fukushi, I | 1 |
| Takeda, K | 1 |
| Hasebe, Y | 1 |
| Pokorski, M | 1 |
| Tatsumi, K | 1 |
| Okada, Y | 1 |
2 other studies available for modafinil and Hypoxia
| Article | Year |
|---|---|
Recovery Mimicking "Ideal" CPAP Adherence Does Not Improve Wakefulness or Cognition in Chronic Murine Models of OSA: Effect of Wake-Promoting Agents.
Topics: Animals; Cognition; Continuous Positive Airway Pressure; Disease Models, Animal; Disorders of Excess | 2023 |
Disharmony between wake- and respiration-promoting activities: effects of modafinil on ventilatory control in rodents.
Topics: Activity Cycles; Animals; Behavior, Animal; Benzhydryl Compounds; Disease Models, Animal; Hypercapni | 2016 |