modafinil has been researched along with Hypercapnia in 2 studies
Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the hypothesis that modafinil enhances resting ventilation as well as the stimulatory ventilatory responses to hypercapnia and hypoxia." | 3.83 | Disharmony between wake- and respiration-promoting activities: effects of modafinil on ventilatory control in rodents. ( Fukushi, I; Hasebe, Y; Okada, Y; Pokorski, M; Takeda, K; Tatsumi, K; Terada, J, 2016) |
| "Hypercapnic respiratory failure is common in advanced chronic obstructive pulmonary disease and is usually treated by nasal ventilation." | 1.40 | The successful treatment of hypercapnic respiratory failure with oral modafinil. ( Adeyemo, S; Farmer, S; Parnell, H; Quirke, G; Varney, V, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Parnell, H | 1 |
| Quirke, G | 1 |
| Farmer, S | 1 |
| Adeyemo, S | 1 |
| Varney, V | 1 |
| Terada, J | 1 |
| Fukushi, I | 1 |
| Takeda, K | 1 |
| Hasebe, Y | 1 |
| Pokorski, M | 1 |
| Tatsumi, K | 1 |
| Okada, Y | 1 |
2 other studies available for modafinil and Hypercapnia
| Article | Year |
|---|---|
The successful treatment of hypercapnic respiratory failure with oral modafinil.
Topics: Administration, Oral; Aged; Aged, 80 and over; Benzhydryl Compounds; Female; Humans; Hypercapnia; Lu | 2014 |
Disharmony between wake- and respiration-promoting activities: effects of modafinil on ventilatory control in rodents.
Topics: Activity Cycles; Animals; Behavior, Animal; Benzhydryl Compounds; Disease Models, Animal; Hypercapni | 2016 |