modafinil has been researched along with Genetic Predisposition in 3 studies
Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Narcolepsy is a chronic sleep disorder that has a typical onset in adolescence and is characterized by excessive daytime sleepiness, which can have severe consequences for the patient." | 2.55 | Narcolepsy. ( Dauvilliers, Y; Jennum, PJ; Knudsen, S; Kornum, BR; Ollila, HM; Overeem, S; Pizza, F, 2017) |
| "Narcolepsy is an emblematic, unique disease within sleep disorders that is characterised by excessive daytime sleepiness, cataplexy and other abnormal manifestations of REM sleep." | 2.48 | [Diagnostic and therapeutic update in narcolepsy]. ( Santamaria-Cano, J, 2012) |
| "Narcolepsy is a neurological disorder characterized by excessive daytime sleepiness and cataplexy." | 2.43 | Molecular genetics and treatment of narcolepsy. ( Dauvilliers, Y; Tafti, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kornum, BR | 1 |
| Knudsen, S | 1 |
| Ollila, HM | 1 |
| Pizza, F | 1 |
| Jennum, PJ | 1 |
| Dauvilliers, Y | 2 |
| Overeem, S | 1 |
| Santamaria-Cano, J | 1 |
| Tafti, M | 1 |
3 reviews available for modafinil and Genetic Predisposition
| Article | Year |
|---|---|
Narcolepsy.
Topics: Adjuvants, Anesthesia; Benzhydryl Compounds; Biomarkers; Cataplexy; Genetic Predisposition to Diseas | 2017 |
[Diagnostic and therapeutic update in narcolepsy].
Topics: Adolescent; Adult; Age of Onset; Animals; Autoimmune Diseases; Benzhydryl Compounds; Cataplexy; Chil | 2012 |
Molecular genetics and treatment of narcolepsy.
Topics: Animals; Antidepressive Agents, Tricyclic; Benzhydryl Compounds; Catechol O-Methyltransferase; Centr | 2006 |