Page last updated: 2024-10-31

modafinil and Drug Overdose

modafinil has been researched along with Drug Overdose in 5 studies

Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"In this case series, clinical effects of modafinil overdoses were generally mild with predominantly tachycardia and CNS toxicity."3.75Toxicity from modafinil ingestion. ( Aleguas, A; Anderson, DA; Borys, D; Griffith, JR; Klein-Schwartz, W; Sawyer, TS; Sollee, D; Spiller, HA, 2009)
"Modafinil is a non-amphetamine stimulant that is prescribed for narcolepsy-associated sleepiness as well as reported off-licence uses among university students looking to improve wakefulness and focus."1.56Hyponatraemia and cerebral oedema due to a modafinil overdose. ( Kaminskaite, V; Kandasamy, RO; May, F, 2020)
"Modafinil is a non-amphetamine wakefulness-promoting agent used for the treatment of various sleep disorders characterized by excessive daytime sleepiness."1.36A retrospective review of supratherapeutic modafinil exposures. ( Cantrell, FL; Carstairs, SD; Clark, RF; Hoffman, J; Urquhart, A, 2010)
"Modafinil (Provigil) is a wake-promoting drug approved for patients with narcolepsy or other causes of excessive daytime sleepiness."1.35Unsuccessful suicide attempt of a 15 year old adolescent with ingestion of 5000 mg modafinil. ( Neuman, G; Pillar, G; Shehadeh, N, 2009)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Reinert, JP1
Dunn, RL1
Kandasamy, RO1
Kaminskaite, V1
May, F1
Spiller, HA1
Borys, D1
Griffith, JR1
Klein-Schwartz, W1
Aleguas, A1
Sollee, D1
Anderson, DA1
Sawyer, TS1
Neuman, G1
Shehadeh, N1
Pillar, G1
Carstairs, SD1
Urquhart, A1
Hoffman, J1
Clark, RF1
Cantrell, FL1

Reviews

1 review available for modafinil and Drug Overdose

ArticleYear
Management of overdoses of loperamide, gabapentin, and modafinil: a literature review.
    Expert review of clinical pharmacology, 2019, Volume: 12, Issue:9

    Topics: Drug Overdose; Emergency Treatment; Gabapentin; Humans; Loperamide; Modafinil; Substance-Related Dis

2019

Other Studies

4 other studies available for modafinil and Drug Overdose

ArticleYear
Hyponatraemia and cerebral oedema due to a modafinil overdose.
    BMJ case reports, 2020, Jul-05, Volume: 13, Issue:7

    Topics: Adult; Brain Edema; Central Nervous System Stimulants; Drug Overdose; Humans; Hyponatremia; Male; Mo

2020
Toxicity from modafinil ingestion.
    Clinical toxicology (Philadelphia, Pa.), 2009, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzhydryl Compounds; Central Nervous System Stimulants;

2009
Unsuccessful suicide attempt of a 15 year old adolescent with ingestion of 5000 mg modafinil.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2009, Aug-15, Volume: 5, Issue:4

    Topics: Abdominal Pain; Adolescent; Benzhydryl Compounds; Central Nervous System Stimulants; Drug Overdose;

2009
A retrospective review of supratherapeutic modafinil exposures.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2010, Volume: 6, Issue:3

    Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Central Nervous System Stimulants; Child; Child, Pres

2010