Page last updated: 2024-10-31

modafinil and Dizziness

modafinil has been researched along with Dizziness in 3 studies

Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.

Dizziness: An imprecise term which may refer to a sense of spatial disorientation, motion of the environment, or lightheadedness.

Research Excerpts

ExcerptRelevanceReference
"Three patients discontinued modafinil because of AEs (nervousness, dizziness)."7.71Modafinil in treatment of fatigue in multiple sclerosis. Results of an open-label study. ( Maida, EM; Rupp, M; Schwarz, S; Zifko, UA; Zipko, HT, 2002)
"Three patients discontinued modafinil because of AEs (nervousness, dizziness)."3.71Modafinil in treatment of fatigue in multiple sclerosis. Results of an open-label study. ( Maida, EM; Rupp, M; Schwarz, S; Zifko, UA; Zipko, HT, 2002)
"Modafinil 200 mg was administered to the treatment group patients 1 h before sedation/analgesia."2.75Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills. ( Boesjes, H; Galvin, E; Hol, J; Klein, J; Ubben, JF; Verbrugge, SJ, 2010)
"Past modafinil use was reported by 2."2.74Modafinil and zolpidem use by emergency medicine residents. ( Ankel, FK; Asplin, BR; Flottemesch, TJ; Ling, LJ; Mason, EJ; McBeth, BD; McNamara, RM, 2009)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Galvin, E1
Boesjes, H1
Hol, J1
Ubben, JF1
Klein, J1
Verbrugge, SJ1
McBeth, BD1
McNamara, RM1
Ankel, FK1
Mason, EJ1
Ling, LJ1
Flottemesch, TJ1
Asplin, BR1
Zifko, UA1
Rupp, M1
Schwarz, S1
Zipko, HT1
Maida, EM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double Blind, Placebo Controlled Evaluation of Modafinil vs Placebo for the Treatment of General Anesthesia Related Delayed Emergence in Patients With the Diagnosis of Obstructive Sleep Apnea[NCT02494102]Phase 4105 participants (Actual)Interventional2016-02-29Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Length of Time From Extubation to Discharge From Postanesthesia Recovery Unit

Length of time of above compared between groups (NCT02494102)
Timeframe: 24 hours

Interventionminutes (Mean)
Placebo53.5
Modafinil61.0

Postanesthesia Quality Recovery Scale Score

Postanesthesia quality recovery scale (PQRS). Component and aggregate scoring on the scale. Measures physiology, nociceptive, emotional activities of daily living cognitive and overall patient perspective. The scale is dimensionless and the aggregate of all individually tested dimensions is scaled from 17-65. A higher value implies improved postanesthesia recovery. Mean difference was assessed in each patient and aggregated thus patients with no difference between pre- and post-operative scores were zeroed (received a zero score if the difference was zero). A negative value was associated with worse outcome. (NCT02494102)
Timeframe: baseline and 6 hours after surgery

Interventionunits on a scale (Mean)
Placebo-5.67
Modafinil-8.91

Trials

2 trials available for modafinil and Dizziness

ArticleYear
Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills.
    Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Anesthesia Recovery Period; Anesthetics, Inha

2010
Modafinil and zolpidem use by emergency medicine residents.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009, Volume: 16, Issue:12

    Topics: Adult; Akathisia, Drug-Induced; Amnesia; Anorexia; Benzhydryl Compounds; Central Nervous System Stim

2009

Other Studies

1 other study available for modafinil and Dizziness

ArticleYear
Modafinil in treatment of fatigue in multiple sclerosis. Results of an open-label study.
    Journal of neurology, 2002, Volume: 249, Issue:8

    Topics: Adult; Anxiety; Benzhydryl Compounds; Central Nervous System Stimulants; Dizziness; Fatigue; Female;

2002