Page last updated: 2024-10-31

modafinil and Compensatory Hyperinsulinemia

modafinil has been researched along with Compensatory Hyperinsulinemia in 1 studies

Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.

Compensatory Hyperinsulinemia: A GLUCOSE-induced HYPERINSULINEMIA, a marker of insulin-resistant state. It is a mechanism to compensate for reduced sensitivity to insulin.

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Buxton, OM	1
Pavlova, M	1
Reid, EW	1
Wang, W	1
Simonson, DC	1
Adler, GK	1

Clinical Trials (5)

Trial Overview

Trial	Enrollment	Study Type	Start Date	Status
Impact of Sleep Restriction on Cardiometabolic Risk Factors in Pre vs Postmenopausal Women[NCT02835261]	54 participants (Actual)	Interventional	2016-09-01	Completed
Sleep Restriction, Impaired Glucose Metabolism, and Performance: The Effects of Modafinil to Counteract the Adverse Metabolic Consequences of Sleep Restriction[NCT00895570]	20 participants (Actual)	Interventional	2005-01-31	Completed
The SLuMBER Study: The Sleep Lengthening and Metabolic Health, Body Composition, Energy Balance and Cardiovascular Risk Study[NCT02787577]	43 participants (Actual)	Interventional	2016-04-30	Completed
Sleep for Health: A Randomized Clinical Trial Examining the Effects of Cognitive Behavioral Therapy for Insomnia on Diabetes Risk[NCT06067139]	300 participants (Anticipated)	Interventional	2023-08-01	Recruiting
Sleep Duration and Glycemic Control in Adolescents With Type 2 Diabetes Mellitus[NCT04213547]	31 participants (Actual)	Interventional	2020-09-16	Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for modafinil and Compensatory Hyperinsulinemia

Article	Year
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010
Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes, 2010, Volume: 59, Issue:9 Topics: Adult; Attention; Basal Metabolism; Benzhydryl Compounds; Blood Glucose; Calorimetry, Indirect; Cent	2010