Page last updated: 2024-10-31
modafinil and Cannabis Abuse
modafinil has been researched along with Cannabis Abuse in 1 studies
Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|
| "Marijuana (cannabis) is the most widely used illicit substance globally, and cannabis use is associated with a range of adverse consequences." | 2.76 | The safety of modafinil in combination with oral ∆9-tetrahydrocannabinol in humans. ( Poling, J; Sofuoglu, M; Sugarman, DE, 2011) |
Research
Studies (1)
| Timeframe | Studies, this research(%) | All Research% |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|
| Sugarman, DE | 1 |
| Poling, J | 1 |
| Sofuoglu, M | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status |
|---|
| Dronabinol Interactions in Humans[NCT00842985] | Early Phase 1 | 53 participants (Actual) | Interventional | 2008-09-30 | Completed |
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Trial Outcomes
CANTAB:CAmbridge Neuropsychological Test Automated Battery RVIP: Rapid Visual Information Processing
"CANTAB RVIP is one component of this computerized battery and is a measure of sustained attention with a working memory component.~This study used two subscales of the RVIP.~RVP A' ( Target sensitivity, a measure of the ability to detect sequences.) The range is from 0-1; bad to good.~RVP B'' ( Response bias, which is a measure of the tendency to respond regardless of whether a target is present.~The range is from -1 to +1 ; bad to good~The numbers represent probabilities as units on a scale." (NCT00842985)
Timeframe: Once for each test session (4 total).
| Intervention | units on a scale (Mean) |
|---|
| THC+Modafinil | 0.91 |
| THC+Placebo | 0.9 |
| Pla+Modafinil | 0.92 |
| Placebo+Placebo | 0.9 |
Trials
1 trial available for modafinil and Cannabis Abuse