Page last updated: 2024-10-31

modafinil and Body Weight

modafinil has been researched along with Body Weight in 9 studies

Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"Results of this pilot trial do not support routine use of modafinil to counteract increased weight and metabolic diseases in patients taking clozapine."9.15Effects of modafinil on weight, glucose and lipid metabolism in clozapine-treated patients with schizophrenia. ( Borba, CP; Cather, C; Copeland, PM; Fan, X; Freudenreich, O; Goff, DC; Henderson, DC; Macklin, E; Wang, X, 2011)
"After an initial patient with cerebral palsy had an apparent dramatic reduction in spasticity when placed on modafinil, a pilot study was undertaken in 10 pediatric patients to confirm or refute the benefit of modafinil in cerebral palsy."7.71Use of modafinil in spastic cerebral palsy. ( Hurst, DL; Lajara-Nanson, W, 2002)
"Modafinil plays a role in vasorelaxation and blocking KCa3."5.43Modafinil improves monocrotaline-induced pulmonary hypertension rat model. ( Cho, MS; Hong, YM; Kim, KC; Lee, H; Suh, SH, 2016)
"Results of this pilot trial do not support routine use of modafinil to counteract increased weight and metabolic diseases in patients taking clozapine."5.15Effects of modafinil on weight, glucose and lipid metabolism in clozapine-treated patients with schizophrenia. ( Borba, CP; Cather, C; Copeland, PM; Fan, X; Freudenreich, O; Goff, DC; Henderson, DC; Macklin, E; Wang, X, 2011)
"After an initial patient with cerebral palsy had an apparent dramatic reduction in spasticity when placed on modafinil, a pilot study was undertaken in 10 pediatric patients to confirm or refute the benefit of modafinil in cerebral palsy."3.71Use of modafinil in spastic cerebral palsy. ( Hurst, DL; Lajara-Nanson, W, 2002)
"Modafinil was generally well tolerated."2.72Modafinil film-coated tablets in children and adolescents with attention-deficit/hyperactivity disorder: results of a randomized, double-blind, placebo-controlled, fixed-dose study followed by abrupt discontinuation. ( Biederman, J; Earl, CQ; Greenhill, LL; Jiang, JG; Lopez, FA; Sedillo, A; Swanson, JM, 2006)
"This randomized, double-blind, placebo-controlled study assessed the efficacy and tolerability of several modafinil dosing regimens in children with attention-deficit/hyperactivity disorder (ADHD) to determine whether modafinil can be given once daily in pediatric ADHD."2.72A comparison of once-daily and divided doses of modafinil in children with attention-deficit/hyperactivity disorder: a randomized, double-blind, and placebo-controlled study. ( Biederman, J; Boellner, SW; Earl, CQ; Lopez, FA; Swanson, JM; Wigal, SB, 2006)
"Modafinil plays a role in vasorelaxation and blocking KCa3."1.43Modafinil improves monocrotaline-induced pulmonary hypertension rat model. ( Cho, MS; Hong, YM; Kim, KC; Lee, H; Suh, SH, 2016)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Murphy, HM1
Ekstrand, D1
Tarchick, M1
Wideman, CH1
Lee, H1
Kim, KC1
Cho, MS1
Suh, SH1
Hong, YM1
Pallier, PN1
Morton, AJ1
Nguyen, TL1
Tian, YH1
You, IJ1
Lee, SY1
Jang, CG1
Henderson, DC1
Freudenreich, O1
Borba, CP1
Wang, X1
Copeland, PM1
Macklin, E1
Fan, X1
Cather, C1
Goff, DC1
Ray, K1
Chatterjee, A1
Panjwani, U1
Kumar, S1
Sahu, S1
Ghosh, S1
Thakur, L1
Anand, JP1
Swanson, JM2
Greenhill, LL1
Lopez, FA2
Sedillo, A1
Earl, CQ2
Jiang, JG1
Biederman, J2
Wigal, SB1
Boellner, SW1
Hurst, DL1
Lajara-Nanson, W1

Trials

3 trials available for modafinil and Body Weight

ArticleYear
Effects of modafinil on weight, glucose and lipid metabolism in clozapine-treated patients with schizophrenia.
    Schizophrenia research, 2011, Volume: 130, Issue:1-3

    Topics: Adult; Analysis of Variance; Benzhydryl Compounds; Blood Glucose; Blood Pressure; Body Weight; Cloza

2011
Modafinil film-coated tablets in children and adolescents with attention-deficit/hyperactivity disorder: results of a randomized, double-blind, placebo-controlled, fixed-dose study followed by abrupt discontinuation.
    The Journal of clinical psychiatry, 2006, Volume: 67, Issue:1

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Benzhydryl Compounds; Body Weight; Centra

2006
A comparison of once-daily and divided doses of modafinil in children with attention-deficit/hyperactivity disorder: a randomized, double-blind, and placebo-controlled study.
    The Journal of clinical psychiatry, 2006, Volume: 67, Issue:5

    Topics: Adolescent; Age Factors; Attention Deficit Disorder with Hyperactivity; Benzhydryl Compounds; Body W

2006

Other Studies

6 other studies available for modafinil and Body Weight

ArticleYear
Modafinil as a cognitive enhancer of spatial working memory in rats.
    Physiology & behavior, 2015, Apr-01, Volume: 142

    Topics: Animals; Benzhydryl Compounds; Body Weight; Eating; Male; Maze Learning; Memory, Short-Term; Modafin

2015
Modafinil improves monocrotaline-induced pulmonary hypertension rat model.
    Pediatric research, 2016, Volume: 80, Issue:1

    Topics: Animals; Benzhydryl Compounds; Body Weight; Cyclic AMP; Disease Models, Animal; Endothelin-1; Gene E

2016
Management of sleep/wake cycles improves cognitive function in a transgenic mouse model of Huntington's disease.
    Brain research, 2009, Jul-07, Volume: 1279

    Topics: Affect; Alprazolam; Animals; Benzhydryl Compounds; Body Weight; Central Nervous System Stimulants; C

2009
Modafinil-induced conditioned place preference via dopaminergic system in mice.
    Synapse (New York, N.Y.), 2011, Volume: 65, Issue:8

    Topics: Animals; Autoradiography; Benzhydryl Compounds; Body Weight; Brain; Central Nervous System Stimulant

2011
Modafinil improves event related potentials P300 and contingent negative variation after 24 h sleep deprivation.
    Life sciences, 2012, Aug-21, Volume: 91, Issue:3-4

    Topics: Actigraphy; Adult; Benzhydryl Compounds; Body Weight; Central Nervous System Stimulants; Cognition;

2012
Use of modafinil in spastic cerebral palsy.
    Journal of child neurology, 2002, Volume: 17, Issue:3

    Topics: Adolescent; Benzhydryl Compounds; Body Weight; Central Nervous System Stimulants; Cerebral Palsy; Ch

2002