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modafinil and Biliary Cirrhosis

modafinil has been researched along with Biliary Cirrhosis in 5 studies

Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.

Research Excerpts

ExcerptRelevanceReference
"To explore, in an open label study, the responses of PBC patients suffering from significant daytime somnolence and associated fatigue to modafinil therapy."9.12An open study of modafinil for the treatment of daytime somnolence and fatigue in primary biliary cirrhosis. ( Jones, DE; Newton, JL, 2007)
"Modafinil may be a potentially effective treatment for primary biliary cirrhosis (PBC)-related fatigue."7.75Modafinil in the treatment of debilitating fatigue in primary biliary cirrhosis: a clinical experience. ( de Jongh, M; Ian Gan, S; Kaplan, MM, 2009)
"To explore, in an open label study, the responses of PBC patients suffering from significant daytime somnolence and associated fatigue to modafinil therapy."5.12An open study of modafinil for the treatment of daytime somnolence and fatigue in primary biliary cirrhosis. ( Jones, DE; Newton, JL, 2007)
"Modafinil may be a potentially effective treatment for primary biliary cirrhosis (PBC)-related fatigue."3.75Modafinil in the treatment of debilitating fatigue in primary biliary cirrhosis: a clinical experience. ( de Jongh, M; Ian Gan, S; Kaplan, MM, 2009)
"There is no specific treatment for fatigue in PBC, but modafinil has shown some potential beneficial effects, such as increased energy levels and decreased total sleep time."2.46Fatigue in primary biliary cirrhosis. ( Abbas, G; Jorgensen, RA; Lindor, KD, 2010)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ian Gan, S1
de Jongh, M1
Kaplan, MM2
Abbas, G1
Jorgensen, RA1
Lindor, KD1
Hardy, T1
MacDonald, C1
Jones, DE2
Newton, JL2
Bonis, PA1

Reviews

1 review available for modafinil and Biliary Cirrhosis

ArticleYear
Fatigue in primary biliary cirrhosis.
    Nature reviews. Gastroenterology & hepatology, 2010, Volume: 7, Issue:6

    Topics: Adipokines; Animals; Autonomic Nervous System; Benzhydryl Compounds; Cytokines; Diagnosis, Different

2010

Trials

1 trial available for modafinil and Biliary Cirrhosis

ArticleYear
An open study of modafinil for the treatment of daytime somnolence and fatigue in primary biliary cirrhosis.
    Alimentary pharmacology & therapeutics, 2007, Feb-15, Volume: 25, Issue:4

    Topics: Adult; Aged; Benzhydryl Compounds; Central Nervous System Stimulants; Disorders of Excessive Somnole

2007

Other Studies

3 other studies available for modafinil and Biliary Cirrhosis

ArticleYear
Modafinil in the treatment of debilitating fatigue in primary biliary cirrhosis: a clinical experience.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:10

    Topics: Adult; Aged; Benzhydryl Compounds; Central Nervous System Stimulants; Fatigue; Female; Follow-Up Stu

2009
A follow-up study of modafinil for the treatment of daytime somnolence and fatigue in primary biliary cirrhosis.
    Liver international : official journal of the International Association for the Study of the Liver, 2010, Volume: 30, Issue:10

    Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Disorders of Excessive Somnolence; Fatigue;

2010
Modafinil for the treatment of fatigue in primary biliary cirrhosis.
    Annals of internal medicine, 2005, Oct-04, Volume: 143, Issue:7

    Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Fatigue; Female; Humans; Liver Cirrhosis, B

2005