Page last updated: 2024-10-31

modafinil and Anesthesia

modafinil has been researched along with Anesthesia in 4 studies

Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
"Modafinil was compared to the indirect dopaminergic drugs, dexamphetamine and methylphenidate, using in vivo differential normal pulse voltammetry with carbon fibre electrodes located in the caudate nucleus to study extracellular catechol level in anaesthetized mice."1.29Lack of pre-synaptic dopaminergic involvement in modafinil activity in anaesthetized mice: in vivo voltammetry studies. ( Boer, C; De Séréville, JE; Duteil, J; Rambert, FA, 1994)
"Modafinil was more active than adrafinil as an inhibitor of pancreatic secretion."1.27Effect of modafinil on pancreatic exocrine secretion in rats. A comparison with adrafinil and related drugs. ( Appia, F; Chariot, J; Rozé, C; Vaille, C, 1987)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morimoto, Y1
Nogami, Y1
Harada, K1
Shiramoto, H1
Moguchi, T1
De Séréville, JE1
Boer, C1
Rambert, FA1
Duteil, J1
Florence, G1
Bonnier, R1
Plagnes, D1
Piérard, C1
Satabin, P1
Pérès, M1
Lagarde, D1
Chariot, J1
Appia, F1
Vaille, C1
Rozé, C1

Other Studies

4 other studies available for modafinil and Anesthesia

ArticleYear
Anesthetic management of a patient with narcolepsy.
    Journal of anesthesia, 2011, Volume: 25, Issue:3

    Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Anti-Inflammatory Agents, Non-Steroid

2011
Lack of pre-synaptic dopaminergic involvement in modafinil activity in anaesthetized mice: in vivo voltammetry studies.
    Neuropharmacology, 1994, Volume: 33, Issue:6

    Topics: alpha-Methyltyrosine; Anesthesia; Animals; Benzhydryl Compounds; Caudate Nucleus; Central Nervous Sy

1994
Effect of modafinil on cerebral blood flow of anaesthetised rats. Comparison with amphetamine.
    Experimental brain research, 2000, Volume: 135, Issue:4

    Topics: Amphetamine; Anesthesia; Animals; Benzhydryl Compounds; Blood Pressure; Central Nervous System Stimu

2000
Effect of modafinil on pancreatic exocrine secretion in rats. A comparison with adrafinil and related drugs.
    Fundamental & clinical pharmacology, 1987, Volume: 1, Issue:4

    Topics: Anesthesia; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Diphenylamine; Duodenu

1987