modafinil has been researched along with Allodynia in 4 studies
Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " On the contrary, suppression of EEG delta power using a wake-promoting agent modafinil significantly attenuated mechanical allodynia." | 3.96 | High cortical delta power correlates with aggravated allodynia by activating anterior cingulate cortex GABAergic neurons in neuropathic pain mice. ( Ge, J; Hong, ZY; Huang, ZL; Lazarus, M; Li, YD; Luo, YJ; Qu, WM; Wang, J; Xu, W, 2020) |
| "Pre-treatment with modafinil prevented sensorimotor neuropathy by raising latencies, MNCV and excitation, reducing TRPA1, TNF-α and IL-1β levels." | 1.56 | The protective effect of modafinil on vincristine-induced peripheral neuropathy in rats: A possible role for TRPA1 receptors. ( Abdollahi, A; Amirkhanloo, F; Dehpour, AR; Karimi, G; Roohbakhsh, A; Yousefi-Manesh, H, 2020) |
| "The consequences of chronic insufficient sleep for health remain uncertain." | 1.46 | Decreased alertness due to sleep loss increases pain sensitivity in mice. ( Alexandre, C; Ferreira, A; Latremoliere, A; Miracca, G; Scammell, TE; Woolf, CJ; Yamamoto, M, 2017) |
| "Modafinil was administered in the doses of 50, 100 or 200 mg/kg once in acute study and it showed significantly increased tail-flick latency (tfl) and paw-licking latency." | 1.40 | Chronic administration of modafinil induces hyperalgesia in mice: reversal by L-NG-nitro-arginine methyl ester and 7-nitroindazole. ( Bhattacharya, SK; Gupta, LK; Gupta, R, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, YD | 1 |
| Ge, J | 1 |
| Luo, YJ | 1 |
| Xu, W | 1 |
| Wang, J | 1 |
| Lazarus, M | 1 |
| Hong, ZY | 1 |
| Qu, WM | 1 |
| Huang, ZL | 1 |
| Amirkhanloo, F | 1 |
| Karimi, G | 1 |
| Yousefi-Manesh, H | 1 |
| Abdollahi, A | 1 |
| Roohbakhsh, A | 1 |
| Dehpour, AR | 1 |
| Alexandre, C | 1 |
| Latremoliere, A | 1 |
| Ferreira, A | 1 |
| Miracca, G | 1 |
| Yamamoto, M | 1 |
| Scammell, TE | 1 |
| Woolf, CJ | 1 |
| Gupta, R | 1 |
| Gupta, LK | 1 |
| Bhattacharya, SK | 1 |
4 other studies available for modafinil and Allodynia
| Article | Year |
|---|---|
High cortical delta power correlates with aggravated allodynia by activating anterior cingulate cortex GABAergic neurons in neuropathic pain mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Cerebral Cortex; Cholinergic Antagonists; Cortical Synchroniz | 2020 |
The protective effect of modafinil on vincristine-induced peripheral neuropathy in rats: A possible role for TRPA1 receptors.
Topics: Animals; Cytokines; Gabapentin; Hyperalgesia; Interleukin-1beta; Modafinil; Neural Conduction; Neura | 2020 |
Decreased alertness due to sleep loss increases pain sensitivity in mice.
Topics: Acute Disease; Analgesics; Animals; Behavior, Animal; Benzhydryl Compounds; Caffeine; Chronic Diseas | 2017 |
Chronic administration of modafinil induces hyperalgesia in mice: reversal by L-NG-nitro-arginine methyl ester and 7-nitroindazole.
Topics: Analgesics; Animals; Behavior, Animal; Benzhydryl Compounds; Central Nervous System Stimulants; Form | 2014 |