Page last updated: 2024-10-31

modafinil and Aging

modafinil has been researched along with Aging in 4 studies

Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Modafinil is a psychostimulant approved for treating excessive sleepiness in adults; off-label uses (e."1.36Age-dependent effects of modafinil on acoustic startle and prepulse inhibition in rats. ( McFadden, SL; Morgan, RE; Zulas, AL, 2010)
"Adrafinil caused an increase in locomotor activity at the three highest doses at both the 2- and 10-h intervals and during both the first (days 1 and 5) and second treatment week (days 9 and 13)."1.31Behavioral activating effects of adrafinil in aged canines. ( Callahan, H; Gruet, P; Milgram, NW; Muggenburg, BA; Murphey, HL; Schneider, M; Siwak, CT; Woehrlé, F, 2000)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Gyertyán, I1
Lubec, J1
Ernyey, AJ1
Gerner, C1
Kassai, F1
Kalaba, P1
Kozma, K1
Cobankovic, I1
Brenner, G1
Wackerlig, J1
Franschitz, E1
Urban, E1
Langer, T1
Malikovic, J1
Lubec, G1
Dance, A1
McFadden, SL1
Zulas, AL1
Morgan, RE1
Siwak, CT1
Gruet, P1
Woehrlé, F1
Schneider, M1
Muggenburg, BA1
Murphey, HL1
Callahan, H1
Milgram, NW1

Other Studies

4 other studies available for modafinil and Aging

ArticleYear
Cognitive profiling and proteomic analysis of the modafinil analogue S-CE-123 in experienced aged rats.
    Scientific reports, 2021, 12-14, Volume: 11, Issue:1

    Topics: Aging; Animals; Benzhydryl Compounds; Cognition; Learning; Male; Modafinil; Prefrontal Cortex; Rats

2021
Smart drugs: A dose of intelligence.
    Nature, 2016, Mar-03, Volume: 531, Issue:7592

    Topics: Aging; Amphetamines; Animals; Benzhydryl Compounds; Biomedical Enhancement; Caffeine; Child; Cogniti

2016
Age-dependent effects of modafinil on acoustic startle and prepulse inhibition in rats.
    Behavioural brain research, 2010, Mar-17, Volume: 208, Issue:1

    Topics: Acoustic Stimulation; Aging; Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Benzhydry

2010
Behavioral activating effects of adrafinil in aged canines.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 66, Issue:2

    Topics: Aging; Animals; Behavior, Animal; Benzhydryl Compounds; Central Nervous System Stimulants; Dogs; Fem

2000