modafinil has been researched along with Acute Disease in 10 studies
Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Modafinil has significant anti-inflammation and anti-oxidation effects." | 7.96 | Modafinil ameliorated pancreatic injury and inflammation through upregulating SNIP1. ( Huang, B; Jiang, X; Li, S; Lu, Y; Qiao, Z; Qin, A; Wu, J, 2020) |
| "To explore whether acute destruction of hypocretin cells in a patient with narcolepsy could be detected and if the course of the disease could be reversed or altered by the use of prednisone for immunosuppression." | 7.72 | Report of a case of immunosuppression with prednisone in an 8-year-old boy with an acute onset of hypocretin-deficiency narcolepsy. ( Einen, M; Hecht, M; Kushida, CA; Lin, L; Mignot, E; Taheri, S; Umetsu, DT, 2003) |
| "Acute interstitial nephritis is a well-recognized cause of acute kidney injury in native kidneys." | 5.39 | A diagnostic conundrum: acute interstitial nephritis due to armodafinil versus acute cellular rejection in a renal transplant recipient--a case report. ( Baradhi, KM; Gohh, R, 2013) |
| " Modafinil has significant anti-inflammation and anti-oxidation effects." | 3.96 | Modafinil ameliorated pancreatic injury and inflammation through upregulating SNIP1. ( Huang, B; Jiang, X; Li, S; Lu, Y; Qiao, Z; Qin, A; Wu, J, 2020) |
| "To explore whether acute destruction of hypocretin cells in a patient with narcolepsy could be detected and if the course of the disease could be reversed or altered by the use of prednisone for immunosuppression." | 3.72 | Report of a case of immunosuppression with prednisone in an 8-year-old boy with an acute onset of hypocretin-deficiency narcolepsy. ( Einen, M; Hecht, M; Kushida, CA; Lin, L; Mignot, E; Taheri, S; Umetsu, DT, 2003) |
| "Lamotrigine was considered to have mixed support." | 2.47 | Pharmacotherapy for the treatment of acute bipolar II depression: current evidence. ( Swartz, HA; Thase, ME, 2011) |
| "Modafinil has the ability to induce the activity of CYP3A4 and consequently decrease the bioavailability of hydrocortisone." | 1.62 | [Adrenal crisis associated with modafinil use]. ( Aquinos, BM; Canteros, TM; de Miguel, V; Fainstein-Day, P; García Arabehety, J; Scibona, P, 2021) |
| "The consequences of chronic insufficient sleep for health remain uncertain." | 1.46 | Decreased alertness due to sleep loss increases pain sensitivity in mice. ( Alexandre, C; Ferreira, A; Latremoliere, A; Miracca, G; Scammell, TE; Woolf, CJ; Yamamoto, M, 2017) |
| "Acute interstitial nephritis is a well-recognized cause of acute kidney injury in native kidneys." | 1.39 | A diagnostic conundrum: acute interstitial nephritis due to armodafinil versus acute cellular rejection in a renal transplant recipient--a case report. ( Baradhi, KM; Gohh, R, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aquinos, BM | 1 |
| García Arabehety, J | 1 |
| Canteros, TM | 1 |
| de Miguel, V | 1 |
| Scibona, P | 1 |
| Fainstein-Day, P | 1 |
| Wu, J | 1 |
| Lu, Y | 1 |
| Qin, A | 1 |
| Li, S | 1 |
| Huang, B | 1 |
| Jiang, X | 1 |
| Qiao, Z | 1 |
| Alexandre, C | 1 |
| Latremoliere, A | 1 |
| Ferreira, A | 1 |
| Miracca, G | 1 |
| Yamamoto, M | 1 |
| Scammell, TE | 1 |
| Woolf, CJ | 1 |
| Baradhi, KM | 1 |
| Gohh, R | 1 |
| Wolf, CE | 1 |
| Poklis, JL | 1 |
| Cumpston, K | 1 |
| Moss, M | 1 |
| Poklis, A | 1 |
| Swartz, HA | 1 |
| Thase, ME | 1 |
| Hecht, M | 1 |
| Lin, L | 1 |
| Kushida, CA | 1 |
| Umetsu, DT | 1 |
| Taheri, S | 1 |
| Einen, M | 1 |
| Mignot, E | 1 |
| Taneja, I | 1 |
| Bruehl, S | 1 |
| Robertson, D | 1 |
| Boërio, D | 1 |
| Lefaucheur, JP | 1 |
| Hogrel, JY | 1 |
| Créange, A | 1 |
| Vytopil, M | 1 |
| Mani, R | 1 |
| Adlakha, A | 1 |
| Zhu, JJ | 1 |
2 reviews available for modafinil and Acute Disease
| Article | Year |
|---|---|
Pharmacotherapy for the treatment of acute bipolar II depression: current evidence.
Topics: Acute Disease; Antidepressive Agents; Antimanic Agents; Benzhydryl Compounds; Benzothiazoles; Bipola | 2011 |
[Pathophysiology and treatment of fatigue in multiple sclerosis].
Topics: 4-Aminopyridine; Acute Disease; Amantadine; Amifampridine; Asthenia; Benzhydryl Compounds; Central N | 2006 |
1 trial available for modafinil and Acute Disease
| Article | Year |
|---|---|
Effect of modafinil on acute pain: a randomized double-blind crossover study.
Topics: Acute Disease; Administration, Oral; Adult; Benzhydryl Compounds; Cross-Over Studies; Double-Blind M | 2004 |
7 other studies available for modafinil and Acute Disease
| Article | Year |
|---|---|
[Adrenal crisis associated with modafinil use].
Topics: Acute Disease; Adrenal Insufficiency; Aged, 80 and over; Female; Glucocorticoids; Humans; Hydrocorti | 2021 |
Modafinil ameliorated pancreatic injury and inflammation through upregulating SNIP1.
Topics: Acute Disease; Animals; Cell Line; Ceruletide; Inflammation; Modafinil; Pancreatitis; Rats; RNA-Bind | 2020 |
Decreased alertness due to sleep loss increases pain sensitivity in mice.
Topics: Acute Disease; Analgesics; Animals; Behavior, Animal; Benzhydryl Compounds; Caffeine; Chronic Diseas | 2017 |
A diagnostic conundrum: acute interstitial nephritis due to armodafinil versus acute cellular rejection in a renal transplant recipient--a case report.
Topics: Acute Disease; Benzhydryl Compounds; Biopsy; Central Nervous System Stimulants; Diagnosis, Different | 2013 |
Acute dilated cardiomyopathy and myocardial injury after combined 4-fluoroamphetamine and modafinil ingestion.
Topics: Acute Disease; Adolescent; Amphetamines; Benzhydryl Compounds; Cardiomyopathy, Dilated; Central Nerv | 2017 |
Report of a case of immunosuppression with prednisone in an 8-year-old boy with an acute onset of hypocretin-deficiency narcolepsy.
Topics: Acute Disease; Benzhydryl Compounds; Carrier Proteins; Central Nervous System Stimulants; Child; Cyc | 2003 |
Acute chorea and hyperthermia after concurrent use of modafinil and tranylcypromine.
Topics: Acute Disease; Adult; Antidepressive Agents; Benzhydryl Compounds; Central Nervous System Stimulants | 2007 |