modafinil has been researched along with Absence Seizure in 5 studies
Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, modafinil at 180 mg/kg exerted an antiepileptic effect in the MES model; however, at the same dosage it increased the seizure stage in the PTZ-kindling model." | 1.34 | Modafinil exerts a dose-dependent antiepileptic effect mediated by adrenergic alpha1 and histaminergic H1 receptors in mice. ( Chen, CR; Huang, ZL; Qiu, MH; Qu, WM; Urade, Y; Xu, XH; Yao, MH, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bahramnjead, E | 1 |
| Kazemi Roodsari, S | 1 |
| Rahimi, N | 1 |
| Etemadi, P | 1 |
| Aghaei, I | 1 |
| Dehpour, AR | 1 |
| Zolkowska, D | 1 |
| Andres-Mach, M | 1 |
| Prisinzano, TE | 1 |
| Baumann, MH | 1 |
| Luszczki, JJ | 1 |
| Smith, BW | 1 |
| Chatterjie, N | 1 |
| Stables, JP | 1 |
| Wang, H | 1 |
| Alexander, GJ | 1 |
| Chen, CR | 1 |
| Qu, WM | 1 |
| Qiu, MH | 1 |
| Xu, XH | 1 |
| Yao, MH | 1 |
| Urade, Y | 1 |
| Huang, ZL | 1 |
5 other studies available for modafinil and Absence Seizure
| Article | Year |
|---|---|
Effects of Modafinil on Clonic Seizure Threshold Induced by Pentylenetetrazole in Mice: Involvement of Glutamate, Nitric oxide, GABA, and Serotonin Pathways.
Topics: Animals; Anticonvulsants; Enzyme Inhibitors; Glutamic Acid; Indazoles; Male; Mice; Modafinil; NG-Nit | 2018 |
Modafinil and its metabolites enhance the anticonvulsant action of classical antiepileptic drugs in the mouse maximal electroshock-induced seizure model.
Topics: Animals; Anticonvulsants; Avoidance Learning; Benzhydryl Compounds; Brain; Carbamazepine; Central Ne | 2015 |
Modafinil for treatment of cognitive side effects of antiepileptic drugs in a patient with seizures and stroke.
Topics: Anticonvulsants; Benzhydryl Compounds; Carbamazepine; Cognition Disorders; Humans; Infarction, Middl | 2003 |
Anti-narcoleptic agent modafinil and its sulfone: a novel facile synthesis and potential anti-epileptic activity.
Topics: Animals; Anticonvulsants; Benzhydryl Compounds; Indicators and Reagents; Mice; Modafinil; Rats; Seiz | 2004 |
Modafinil exerts a dose-dependent antiepileptic effect mediated by adrenergic alpha1 and histaminergic H1 receptors in mice.
Topics: Animals; Benzhydryl Compounds; Disease Models, Animal; Electroencephalography; Electroshock; Epileps | 2007 |