moclobemide has been researched along with Syndrome in 20 studies
Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Combination treatment with fluoxetine and moclobemide did not provide any indication of development of the "serotonin syndrome." | 9.08 | Pharmacokinetic and pharmacodynamic interactions between fluoxetine and moclobemide in the investigation of development of the "serotonin syndrome". ( Amrein, R; Dingemanse, J; Gieschke, R; Guentert, T; Wallnöfer, A, 1998) |
| "The serotonin syndrome is frequently characterized by minor neurologic manifestations that regress rapidly (such as confusion, tremor, ." | 5.30 | Serotonin syndrome due to an overdose of moclobemide and clomipramine. A potentially life-threatening association. ( Desachy, A; François, B; Gastinne, H; Lachatre, G; Marquet, P; Roustan, J, 1997) |
| "Combination treatment with fluoxetine and moclobemide did not provide any indication of development of the "serotonin syndrome." | 5.08 | Pharmacokinetic and pharmacodynamic interactions between fluoxetine and moclobemide in the investigation of development of the "serotonin syndrome". ( Amrein, R; Dingemanse, J; Gieschke, R; Guentert, T; Wallnöfer, A, 1998) |
| "We report a case of severe serotonin syndrome after self-poisoning with two antidepressant drugs, paroxetine (a selective inhibitor of serotonin reuptake) and moclobemide (a reversible inhibitor of MAO-A)." | 3.69 | [Serotonin syndrome in acute poisoning with antidepressive agents]. ( Cabot, C; Cathala, B; Fabre, M; Robert, P; Senard, JM, 1996) |
| "Fibromyalgia (FM) syndrome is a chronic condition of unknown aetiology characterised by musculoskeletal pain that often co-exists with sleep disturbance, cognitive dysfunction and fatigue." | 2.48 | Monoamine oxidase inhibitors (MAOIs) for fibromyalgia syndrome. ( Nishishinya, MB; Tort, S; Urrútia, G; Walitt, B, 2012) |
| "Serotonin syndrome is a potentially life-threatening complication of psychopharmacological drug therapy." | 2.40 | Serotonin syndrome and drug combinations: focus on MAOI and RIMA. ( Hilton, SE; Maradit, H; Möller, HJ, 1997) |
| "The serotonin syndrome is frequently characterized by minor neurologic manifestations that regress rapidly (such as confusion, tremor, ." | 1.30 | Serotonin syndrome due to an overdose of moclobemide and clomipramine. A potentially life-threatening association. ( Desachy, A; François, B; Gastinne, H; Lachatre, G; Marquet, P; Roustan, J, 1997) |
| " We discuss a possible relation between serotonin syndrome and a highly dosed combination therapy with moclobemide." | 1.29 | [Depressive stupor--malignant neuroleptic syndrome--serotonin syndrome. A case contribution to a difficult differential diagnosis]. ( König, F; Löble, M; Wolfersdorf, M, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 19 (95.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tort, S | 1 |
| Urrútia, G | 1 |
| Nishishinya, MB | 1 |
| Walitt, B | 1 |
| Power, BM | 1 |
| Pinder, M | 1 |
| Hackett, LP | 1 |
| Ilett, KF | 1 |
| Gillman, PK | 2 |
| Kuisma, MJ | 1 |
| Hernandez, AF | 1 |
| Montero, MN | 1 |
| Pla, A | 1 |
| Villanueva, E | 1 |
| Brodribb, TR | 1 |
| Downey, M | 1 |
| Gilbar, PJ | 1 |
| Spoov, J | 1 |
| Suominen, JY | 1 |
| Lahdelma, RL | 1 |
| Katila, H | 1 |
| Kymäläinen, O | 1 |
| Isometsä, E | 1 |
| Liukko, H | 1 |
| Auvinen, J | 1 |
| Spigset, O | 1 |
| Mjörndal, T | 1 |
| Lövheim, O | 1 |
| Fischer, P | 1 |
| König, F | 1 |
| Löble, M | 1 |
| Wolfersdorf, M | 1 |
| Robert, P | 1 |
| Senard, JM | 1 |
| Fabre, M | 1 |
| Cabot, C | 1 |
| Cathala, B | 1 |
| François, B | 1 |
| Marquet, P | 1 |
| Desachy, A | 1 |
| Roustan, J | 1 |
| Lachatre, G | 1 |
| Gastinne, H | 1 |
| Hilton, SE | 1 |
| Maradit, H | 1 |
| Möller, HJ | 1 |
| Ferrer-Dufol, A | 1 |
| Perez-Aradros, C | 1 |
| Murillo, EC | 1 |
| Marques-Alamo, JM | 1 |
| Dingemanse, J | 1 |
| Wallnöfer, A | 1 |
| Gieschke, R | 1 |
| Guentert, T | 1 |
| Amrein, R | 1 |
| Roxanas, MG | 1 |
| Machado, JF | 1 |
| Finge, T | 1 |
| Malavialle, C | 1 |
| Lambert, J | 1 |
| Dardennes, RM | 1 |
| Even, C | 1 |
| Ballon, N | 1 |
| Bange, F | 1 |
| Chaudhry, HR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cannabidiol for Fibromyalgia -The CANNFIB Trial Protocol for a Randomized, Double-blind, Placebo-controlled, Parallel-group, Single-center Trial[NCT04729179] | Phase 3 | 200 participants (Anticipated) | Interventional | 2021-03-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for moclobemide and Syndrome
| Article | Year |
|---|---|
Monoamine oxidase inhibitors (MAOIs) for fibromyalgia syndrome.
Topics: Adult; Carbazoles; Fibromyalgia; Humans; Moclobemide; Monoamine Oxidase Inhibitors; Randomized Contr | 2012 |
Serotonin syndrome and drug combinations: focus on MAOI and RIMA.
Topics: Autonomic Nervous System Diseases; Benzamides; Brain Stem; Drug Therapy, Combination; Humans; Moclob | 1997 |
2 trials available for moclobemide and Syndrome
| Article | Year |
|---|---|
Do reversed depressive symptoms occur together as a syndrome?
Topics: Adult; Affect; Antidepressive Agents, Tricyclic; Appetite; Benzamides; Depressive Disorder; Female; | 1993 |
Pharmacokinetic and pharmacodynamic interactions between fluoxetine and moclobemide in the investigation of development of the "serotonin syndrome".
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Antidepressive Agents; Benzamides; Blood Platelets; Drug Admi | 1998 |
16 other studies available for moclobemide and Syndrome
| Article | Year |
|---|---|
Fatal serotonin syndrome following a combined overdose of moclobemide, clomipramine and fluoxetine.
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricy | 1995 |
Possible serotonin syndrome with moclobemide and pethidine.
Topics: Aged; Akathisia, Drug-Induced; Antidepressive Agents; Benzamides; Female; Humans; Meperidine; Moclob | 1995 |
Fatal serotonin syndrome with trismus.
Topics: Adult; Antidepressive Agents; Benzamides; Drug Interactions; Fatal Outcome; Female; Humans; Moclobem | 1995 |
Fatal moclobemide overdose or death caused by serotonin syndrome?
Topics: Adult; Antidepressive Agents; Benzamides; Cause of Death; Clomipramine; Drug Interactions; Drug Over | 1995 |
Efficacy and adverse effects of moclobemide.
Topics: Adult; Benzamides; Drug Interactions; Female; Humans; Imipramine; Moclobemide; Monoamine Oxidase Inh | 1994 |
Serotonin syndrome caused by a moclobemide-clomipramine interaction.
Topics: Aged; Benzamides; Clomipramine; Drug Interactions; Female; Humans; Moclobemide; Monoamine Oxidase In | 1993 |
Serotonin syndrome in the elderly after antidepressive monotherapy.
Topics: Aged; Aged, 80 and over; Akathisia, Drug-Induced; Antidepressive Agents, Second-Generation; Benzamid | 1995 |
[Depressive stupor--malignant neuroleptic syndrome--serotonin syndrome. A case contribution to a difficult differential diagnosis].
Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzamides; Depressive Disorder; Diagnosis, | 1996 |
[Serotonin syndrome in acute poisoning with antidepressive agents].
Topics: Adult; Antidepressive Agents; Benzamides; Humans; Male; Moclobemide; Muscle Hypertonia; Paroxetine; | 1996 |
Serotonin syndrome due to an overdose of moclobemide and clomipramine. A potentially life-threatening association.
Topics: Antidepressive Agents; Benzamides; Clomipramine; Drug Interactions; Drug Overdose; Female; Humans; M | 1997 |
Fatal serotonin syndrome caused by moclobemide-clomipramine overdose.
Topics: Adult; Benzamides; Clomipramine; Clorazepate Dipotassium; Drug Interactions; Drug Overdose; Fatal Ou | 1998 |
Serotonin syndrome--clomipramine too soon after moclobemide?
Topics: Adult; Benzamides; Central Nervous System Diseases; Clomipramine; Depressive Disorder; Drug Interact | 1997 |
Serotonin syndrome in combined moclobemide and venlafaxine ingestion.
Topics: Adult; Benzamides; Central Nervous System Depressants; Cyclohexanols; Drug Interactions; Drug Overdo | 1998 |
[Fatal form of serotonin syndrome].
Topics: Adult; Benzamides; Clomipramine; Fatal Outcome; Female; Humans; Moclobemide; Monoamine Oxidase Inhib | 1997 |
Serotonin syndrome caused by a clomipramine-moclobemide interaction.
Topics: Adult; Benzamides; Central Nervous System Diseases; Clomipramine; Confusion; Drug Interactions; Fema | 1998 |
Clinical use of moclobemide in Kleine-Levin syndrome.
Topics: Benzamides; Depressive Disorder; Disorders of Excessive Somnolence; Humans; Hyperphagia; Male; Moclo | 1992 |