moclobemide has been researched along with Substance Withdrawal Syndrome in 3 studies
Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.
Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Effects of chronic moclobemide administration on ethanol consumption, blood ethanol level, motor coordination and seizures induced by an audiogenic stimulus during ethanol withdrawal syndrome have been investigated in chronically ethanol intoxicated rats." | 3.69 | Investigation of the effects of moclobemide in chronic ethanol feeding rats. ( Ayhan, IH; Celik, T; Sever, B; Uzbay, IT, 1995) |
| "Sertraline treatment did not modify the symptoms, which may suggest different mechanisms with regard to different antidepressant drug discontinuation syndromes." | 1.31 | Moclobemide discontinuation syndrome predominantly presenting with influenza-like symptoms. ( Berney, P; Curtin, F; Kaufmann, C, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Curtin, F | 1 |
| Berney, P | 1 |
| Kaufmann, C | 1 |
| Steiger, A | 1 |
| Benkert, O | 1 |
| Holsboer, F | 1 |
| Uzbay, IT | 1 |
| Sever, B | 1 |
| Celik, T | 1 |
| Ayhan, IH | 1 |
1 trial available for moclobemide and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Effects of long-term treatment with the MAO-A inhibitor moclobemide on sleep EEG and nocturnal hormonal secretion in normal men.
Topics: Adult; Benzamides; Dose-Response Relationship, Drug; Drug Administration Schedule; Electroencephalog | 1994 |
2 other studies available for moclobemide and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Moclobemide discontinuation syndrome predominantly presenting with influenza-like symptoms.
Topics: Depressive Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; | 2002 |
Investigation of the effects of moclobemide in chronic ethanol feeding rats.
Topics: Alcohol Drinking; Animals; Benzamides; Body Weight; Central Nervous System Depressants; Ethanol; Mal | 1995 |