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moclobemide and Sleep Initiation and Maintenance Disorders

moclobemide has been researched along with Sleep Initiation and Maintenance Disorders in 4 studies

Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.

Sleep Initiation and Maintenance Disorders: Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.

Research Excerpts

ExcerptRelevanceReference
"An international, multicentre, double blind parallel group study compared the tolerability and efficacy of moclobemide with the selective serotonin reuptake inhibitor (SSRI) fluoxetine for panic disorder."9.09Moclobemide and fluoxetine for panic disorder. International Panic Disorder Study Group. ( Behnke, K; Bouwer, C; Tiller, JW, 1999)
"An international, multicentre, double blind parallel group study compared the tolerability and efficacy of moclobemide with the selective serotonin reuptake inhibitor (SSRI) fluoxetine for panic disorder."5.09Moclobemide and fluoxetine for panic disorder. International Panic Disorder Study Group. ( Behnke, K; Bouwer, C; Tiller, JW, 1999)
" There were 188 adverse events: insomnia, dizziness, headache, nausea, dry mouth and myoclonic jerks were the most common."2.68Safety and tolerability of combined treatment with moclobemide and SSRIs: a systematic study of 50 patients. ( Hawley, CJ; McPhee, S; Pattinson, HA; Quick, SJ; Ratnam, S, 1996)
" A metaregression did not reveal a statistically significant relation between the mean moclobemide dosage for each study and the risk ratio for response rates."2.43A metaanalysis of clinical trials comparing moclobemide with selective serotonin reuptake inhibitors for the treatment of major depressive disorder. ( Fava, M; Papakostas, GI, 2006)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Papakostas, GI1
Fava, M1
Hawley, CJ1
Quick, SJ1
Ratnam, S1
Pattinson, HA1
McPhee, S1
Versiani, M1
Nardi, AE1
Mundim, FD1
Pinto, S1
Saboya, E1
Kovacs, R1
Tiller, JW1
Bouwer, C1
Behnke, K1

Reviews

1 review available for moclobemide and Sleep Initiation and Maintenance Disorders

ArticleYear
A metaanalysis of clinical trials comparing moclobemide with selective serotonin reuptake inhibitors for the treatment of major depressive disorder.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2006, Volume: 51, Issue:12

    Topics: Depressive Disorder, Major; Disorders of Excessive Somnolence; Fatigue; Headache; Humans; Imipramine

2006

Trials

3 trials available for moclobemide and Sleep Initiation and Maintenance Disorders

ArticleYear
Safety and tolerability of combined treatment with moclobemide and SSRIs: a systematic study of 50 patients.
    International clinical psychopharmacology, 1996, Volume: 11, Issue:3

    Topics: Adult; Benzamides; Depressive Disorder; Drug Therapy, Combination; Female; Fluoxetine; Headache; Hum

1996
The long-term treatment of social phobia with moclobemide.
    International clinical psychopharmacology, 1996, Volume: 11 Suppl 3

    Topics: Adolescent; Adult; Benzamides; Female; Headache; Humans; Male; Middle Aged; Moclobemide; Monoamine O

1996
Moclobemide and fluoxetine for panic disorder. International Panic Disorder Study Group.
    European archives of psychiatry and clinical neuroscience, 1999, Volume: 249 Suppl 1

    Topics: Adult; Benzamides; Double-Blind Method; Female; Fluoxetine; Headache; Humans; Male; Moclobemide; Mon

1999