moclobemide has been researched along with Sexual Dysfunctions, Psychological in 5 studies
Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.
Sexual Dysfunctions, Psychological: Disturbances in sexual desire and the psychophysiologic changes that characterize the sexual response cycle and cause marked distress and interpersonal difficulty. (APA, DSM-IV, 1994)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Five patients with depressive disorder who experienced sexual side effects during treatment with standard doses of fluoxetine (20 to 40 mg per day)." | 3.70 | Switching to moclobemide to reverse fluoxetine-induced sexual dysfunction in patients with depression. ( Ramasubbu, R, 1999) |
| " The purpose of this report is to evaluate disturbances in sexual drive/desire and arousal/orgasm in 107 patients who met criteria for major depressive disorder and received treatment with either moclobemide, paroxetine, sertraline, or venlafaxine." | 3.70 | Antidepressant-induced sexual dysfunction during treatment with moclobemide, paroxetine, sertraline, and venlafaxine. ( Bacchiochi, JR; Bagby, RM; Dickens, SE; Eisfeld, BS; Kennedy, SH, 2000) |
| " Doubling the low dosage in non-responders after 3 weeks resulted in a statistically significant improvement of CGI in the moclobemide group by comparison with the fluoxetine group at study end, suggesting that 600 mg moclobemide/day can still improve the patient's condition, while 40 mg fluoxetine/day does not." | 2.68 | Moclobemide versus fluoxetine for a major depressive episode. ( Haazen, L; Janne, P; Mirel, J; Parent, M; Reynaert, C, 1995) |
| "Antidepressant-induced adverse sexual effects are becoming more frequently reported by patients who require pharmacotherapy." | 2.39 | Sexual side effects of antidepressants: a review. ( Assalian, P; Margolese, HC, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reynaert, C | 1 |
| Parent, M | 1 |
| Mirel, J | 1 |
| Janne, P | 1 |
| Haazen, L | 1 |
| Margolese, HC | 1 |
| Assalian, P | 1 |
| Ramasubbu, R | 1 |
| Kennedy, SH | 1 |
| Eisfeld, BS | 1 |
| Dickens, SE | 1 |
| Bacchiochi, JR | 1 |
| Bagby, RM | 1 |
1 review available for moclobemide and Sexual Dysfunctions, Psychological
| Article | Year |
|---|---|
Sexual side effects of antidepressants: a review.
Topics: Antidepressive Agents, Tricyclic; Benzamides; Bupropion; Female; Humans; Libido; Male; Moclobemide; | 1996 |
1 trial available for moclobemide and Sexual Dysfunctions, Psychological
| Article | Year |
|---|---|
Moclobemide versus fluoxetine for a major depressive episode.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Benzamides; Depressive Disorder; Dose-Response Relat | 1995 |
3 other studies available for moclobemide and Sexual Dysfunctions, Psychological
| Article | Year |
|---|---|
Switching to moclobemide to reverse fluoxetine-induced sexual dysfunction in patients with depression.
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Benzamides; Depressive Disor | 1999 |
[Various forms of risk factors of antidepressive agents for influencing sexual functions. Moclobemid is first choice for the therapy of sexually active patients with depression].
Topics: Antidepressive Agents; Anxiety; Benzamides; Depression; Depressive Disorder; Female; Humans; Male; M | 1999 |
Antidepressant-induced sexual dysfunction during treatment with moclobemide, paroxetine, sertraline, and venlafaxine.
Topics: Adult; Cyclohexanols; Depressive Disorder; Female; Humans; Libido; Male; Middle Aged; Moclobemide; M | 2000 |