moclobemide has been researched along with Serotonin Syndrome in 17 studies
Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.
Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The serotonin syndrome is caused by a drug-induced increase of the intrasynaptic serotonin concentration." | 5.33 | [The serotonin syndrome. Fatal course of intoxication with citalopram and moclobemide]. ( Cassens, S; Neumann, P; Nickel, EA; Quintel, M, 2006) |
| "Serotonin syndrome is caused by excess serotonin in the central nervous system." | 1.37 | [Serotonin syndrome in the course of drug-poisoning--case presentation]. ( Kostek, H; Kujawa, A; Majewska, M; Pyra, E; Szponar, J, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 10 (58.82) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ringland, C | 1 |
| Mant, A | 1 |
| McGettigan, P | 1 |
| Mitchell, P | 1 |
| Kelman, C | 1 |
| Buckley, N | 1 |
| Pearson, SA | 1 |
| Kłys, M | 1 |
| Kowalski, P | 1 |
| Rojek, S | 1 |
| Gross, A | 1 |
| Pilgrim, JL | 1 |
| Gerostamoulos, D | 1 |
| Woodford, N | 1 |
| Drummer, OH | 1 |
| Majewska, M | 1 |
| Szponar, J | 1 |
| Pyra, E | 1 |
| Kostek, H | 1 |
| Kujawa, A | 1 |
| Höjer, J | 2 |
| Personne, M | 2 |
| Skagius, AS | 2 |
| Hansson, O | 2 |
| Vuori, E | 1 |
| Henry, JA | 1 |
| Ojanperä, I | 1 |
| Nieminen, R | 1 |
| Savolainen, T | 1 |
| Wahlsten, P | 1 |
| Jäntti, M | 1 |
| Gillman, K | 1 |
| Zivanović, O | 1 |
| Till, E | 1 |
| Cassens, S | 1 |
| Nickel, EA | 1 |
| Quintel, M | 1 |
| Neumann, P | 1 |
| Jimenez-Genchi, A | 1 |
| Rogde, S | 1 |
| Hilberg, T | 1 |
| Teige, B | 1 |
| Birkenhäger, TK | 1 |
| Moleman, P | 1 |
| FitzSimmons, CR | 1 |
| Metha, S | 1 |
| Gumà, M | 1 |
| Clemente, F | 1 |
| Segura, A | 1 |
| Costa, J | 1 |
| Chambost, M | 1 |
| Liron, L | 1 |
| Peillon, D | 1 |
| Combe, C | 1 |
| Dams, R | 1 |
| Benijts, TH | 1 |
| Lambert, WE | 1 |
| Van Bocxlaer, JF | 1 |
| Van Varenbergh, D | 1 |
| Van Peteghem, C | 1 |
| De Leenheer, AP | 1 |
2 reviews available for moclobemide and Serotonin Syndrome
| Article | Year |
|---|---|
[Two new antidepressants: mirtazapine and venlafaxine].
Topics: Adrenergic alpha-Antagonists; Benzamides; Cyclohexanols; Depressive Disorder; Drug Interactions; Fem | 1999 |
[The serotoninergic syndrome: moclobemide and citalopram].
Topics: Adult; Citalopram; Drug Interactions; Humans; Male; Moclobemide; Monoamine Oxidase Inhibitors; Selec | 1999 |
15 other studies available for moclobemide and Serotonin Syndrome
| Article | Year |
|---|---|
Uncovering the potential risk of serotonin toxicity in Australian veterans using pharmaceutical claims data.
Topics: Aged; Australia; Databases, Factual; Drug Prescriptions; Female; Humans; Male; Medical Errors; Middl | 2008 |
Death of a female cocaine user due to the serotonin syndrome following moclobemide-venlafaxine overdose.
Topics: Cocaine; Cocaine-Related Disorders; Cyclohexanols; Dopamine Uptake Inhibitors; Drug Overdose; Female | 2009 |
Serotonin toxicity involving MDMA (ecstasy) and moclobemide.
Topics: Adult; Coronary Artery Disease; Forensic Toxicology; Hallucinogens; Humans; Liver; Lung; Male; Middl | 2012 |
[Serotonin syndrome in the course of drug-poisoning--case presentation].
Topics: Alcoholic Intoxication; Alkaloids; Azocines; Bradycardia; Cyclohexanols; Depressive Disorder; Electr | 2011 |
[Serotonin syndrome--several cases of this often overlooked diagnosis].
Topics: Adult; Antidepressive Agents; Diagnosis, Differential; Drug Overdose; Female; Humans; Male; Moclobem | 2002 |
Death following ingestion of MDMA (ecstasy) and moclobemide.
Topics: Adolescent; Adult; Drug Interactions; Drug Overdose; Fatal Outcome; Female; Hallucinogens; Humans; M | 2003 |
Moclobemide and the risk of serotonin toxicity (or serotonin syndrome).
Topics: Animals; Antidepressive Agents; Drug Combinations; Drug Interactions; Humans; Moclobemide; Monoamine | 2004 |
[Serotonin syndrome--a case account].
Topics: Antidepressive Agents; Depressive Disorder; Humans; Male; Middle Aged; Moclobemide; Monoamine Oxidas | 1992 |
[The serotonin syndrome. Fatal course of intoxication with citalopram and moclobemide].
Topics: Adult; Citalopram; Electrocardiography; Emergency Medical Services; Fatal Outcome; Female; Humans; M | 2006 |
Immediate switching from moclobemide to duloxetine may induce serotonin syndrome.
Topics: Antidepressive Agents; Depressive Disorder, Major; Drug Interactions; Duloxetine Hydrochloride; Fema | 2006 |
Fatal combined intoxication with new antidepressants. Human cases and an experimental study of postmortem moclobemide redistribution.
Topics: Adult; Animals; Antidepressive Agents; Autopsy; Benzamides; Cause of Death; Disease Models, Animal; | 1999 |
Serotonin syndrome caused by overdose with paroxetine and moclobemide.
Topics: Adult; Benzamides; Disease-Free Survival; Drug Overdose; Emergency Treatment; Humans; Male; Moclobem | 1999 |
[Serotonin syndrome during fluoxetine poisoning in a patient taking moclobemide].
Topics: Adult; Anesthetics, Intravenous; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, | 2000 |
A fatal case of serotonin syndrome after combined moclobemide-citalopram intoxication.
Topics: Adult; Antidepressive Agents; Chromatography, High Pressure Liquid; Citalopram; Drug Combinations; E | 2001 |
[Serotonin syndrome. Several cases of this often overlooked diagnosis].
Topics: Adult; Antidepressive Agents; Diagnosis, Differential; Drug Overdose; Female; Humans; Male; Moclobem | 2002 |