moclobemide has been researched along with Psychotic Disorders in 4 studies
Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.
Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)
Excerpt | Relevance | Reference |
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"The study was designed as a 6-week, two-center, fixed-dose, comparison study of 400 mg/day of amisulpride versus 300 mg/day of moclobemide as an adjunctive treatment in 53 schizophrenia and schizoaffective disorder patients (diagnosed according to DSM-IV) suffering from CIS." | 5.15 | Amisulpride versus moclobemide in treatment of clozapine-induced hypersalivation. ( Bergman, J; Kreinin, A; Lerner, V; Libov, I; Miodownik, C; Shestakova, D; Sokolik, S, 2011) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (50.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Mattsson, C | 1 |
Andreasson, T | 1 |
Waters, N | 1 |
Sonesson, C | 1 |
Kreinin, A | 1 |
Miodownik, C | 1 |
Sokolik, S | 1 |
Shestakova, D | 1 |
Libov, I | 1 |
Bergman, J | 1 |
Lerner, V | 1 |
Birkenhäger, TK | 1 |
Moleman, P | 1 |
Angst, J | 1 |
Stabl, M | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Comparison of Benzamide Derivates (Amisulpride, Moclobemide and Tiapride) as Treatment of Clozapine-induced Hypersalivation: Pilot Double Phase Study: Open and Double-blind[NCT00534573] | Phase 3 | 54 participants (Actual) | Interventional | 2008-11-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
2 reviews available for moclobemide and Psychotic Disorders
Article | Year |
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[Two new antidepressants: mirtazapine and venlafaxine].
Topics: Adrenergic alpha-Antagonists; Benzamides; Cyclohexanols; Depressive Disorder; Drug Interactions; Fem | 1999 |
Efficacy of moclobemide in different patient groups: a meta-analysis of studies.
Topics: Adult; Aged; Anti-Anxiety Agents; Antidepressive Agents; Benzamides; Benzodiazepines; Depressive Dis | 1992 |
1 trial available for moclobemide and Psychotic Disorders
Article | Year |
---|---|
Amisulpride versus moclobemide in treatment of clozapine-induced hypersalivation.
Topics: Adult; Aged; Amisulpride; Antipsychotic Agents; Clozapine; Cross-Over Studies; Female; Humans; Male; | 2011 |
1 other study available for moclobemide and Psychotic Disorders
Article | Year |
---|---|
Systematic in vivo screening of a series of 1-propyl-4-arylpiperidines against dopaminergic and serotonergic properties in rat brain: a scaffold-jumping approach.
Topics: Animals; Behavior, Animal; Brain; Dopamine; Dopamine Agents; Dopamine D2 Receptor Antagonists; Locom | 2012 |