Page last updated: 2024-10-31

moclobemide and Psychotic Disorders

moclobemide has been researched along with Psychotic Disorders in 4 studies

Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.

Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)

Research Excerpts

ExcerptRelevanceReference
"The study was designed as a 6-week, two-center, fixed-dose, comparison study of 400 mg/day of amisulpride versus 300 mg/day of moclobemide as an adjunctive treatment in 53 schizophrenia and schizoaffective disorder patients (diagnosed according to DSM-IV) suffering from CIS."5.15Amisulpride versus moclobemide in treatment of clozapine-induced hypersalivation. ( Bergman, J; Kreinin, A; Lerner, V; Libov, I; Miodownik, C; Shestakova, D; Sokolik, S, 2011)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mattsson, C1
Andreasson, T1
Waters, N1
Sonesson, C1
Kreinin, A1
Miodownik, C1
Sokolik, S1
Shestakova, D1
Libov, I1
Bergman, J1
Lerner, V1
Birkenhäger, TK1
Moleman, P1
Angst, J1
Stabl, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Benzamide Derivates (Amisulpride, Moclobemide and Tiapride) as Treatment of Clozapine-induced Hypersalivation: Pilot Double Phase Study: Open and Double-blind[NCT00534573]Phase 354 participants (Actual)Interventional2008-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for moclobemide and Psychotic Disorders

ArticleYear
[Two new antidepressants: mirtazapine and venlafaxine].
    Nederlands tijdschrift voor geneeskunde, 1999, May-01, Volume: 143, Issue:18

    Topics: Adrenergic alpha-Antagonists; Benzamides; Cyclohexanols; Depressive Disorder; Drug Interactions; Fem

1999
Efficacy of moclobemide in different patient groups: a meta-analysis of studies.
    Psychopharmacology, 1992, Volume: 106 Suppl

    Topics: Adult; Aged; Anti-Anxiety Agents; Antidepressive Agents; Benzamides; Benzodiazepines; Depressive Dis

1992

Trials

1 trial available for moclobemide and Psychotic Disorders

ArticleYear
Amisulpride versus moclobemide in treatment of clozapine-induced hypersalivation.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2011, Volume: 12, Issue:8

    Topics: Adult; Aged; Amisulpride; Antipsychotic Agents; Clozapine; Cross-Over Studies; Female; Humans; Male;

2011

Other Studies

1 other study available for moclobemide and Psychotic Disorders

ArticleYear
Systematic in vivo screening of a series of 1-propyl-4-arylpiperidines against dopaminergic and serotonergic properties in rat brain: a scaffold-jumping approach.
    Journal of medicinal chemistry, 2012, Nov-26, Volume: 55, Issue:22

    Topics: Animals; Behavior, Animal; Brain; Dopamine; Dopamine Agents; Dopamine D2 Receptor Antagonists; Locom

2012