moclobemide has been researched along with Psychotic Disorders in 4 studies
Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.
Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The study was designed as a 6-week, two-center, fixed-dose, comparison study of 400 mg/day of amisulpride versus 300 mg/day of moclobemide as an adjunctive treatment in 53 schizophrenia and schizoaffective disorder patients (diagnosed according to DSM-IV) suffering from CIS." | 5.15 | Amisulpride versus moclobemide in treatment of clozapine-induced hypersalivation. ( Bergman, J; Kreinin, A; Lerner, V; Libov, I; Miodownik, C; Shestakova, D; Sokolik, S, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mattsson, C | 1 |
| Andreasson, T | 1 |
| Waters, N | 1 |
| Sonesson, C | 1 |
| Kreinin, A | 1 |
| Miodownik, C | 1 |
| Sokolik, S | 1 |
| Shestakova, D | 1 |
| Libov, I | 1 |
| Bergman, J | 1 |
| Lerner, V | 1 |
| Birkenhäger, TK | 1 |
| Moleman, P | 1 |
| Angst, J | 1 |
| Stabl, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Benzamide Derivates (Amisulpride, Moclobemide and Tiapride) as Treatment of Clozapine-induced Hypersalivation: Pilot Double Phase Study: Open and Double-blind[NCT00534573] | Phase 3 | 54 participants (Actual) | Interventional | 2008-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for moclobemide and Psychotic Disorders
| Article | Year |
|---|---|
[Two new antidepressants: mirtazapine and venlafaxine].
Topics: Adrenergic alpha-Antagonists; Benzamides; Cyclohexanols; Depressive Disorder; Drug Interactions; Fem | 1999 |
Efficacy of moclobemide in different patient groups: a meta-analysis of studies.
Topics: Adult; Aged; Anti-Anxiety Agents; Antidepressive Agents; Benzamides; Benzodiazepines; Depressive Dis | 1992 |
1 trial available for moclobemide and Psychotic Disorders
| Article | Year |
|---|---|
Amisulpride versus moclobemide in treatment of clozapine-induced hypersalivation.
Topics: Adult; Aged; Amisulpride; Antipsychotic Agents; Clozapine; Cross-Over Studies; Female; Humans; Male; | 2011 |
1 other study available for moclobemide and Psychotic Disorders
| Article | Year |
|---|---|
Systematic in vivo screening of a series of 1-propyl-4-arylpiperidines against dopaminergic and serotonergic properties in rat brain: a scaffold-jumping approach.
Topics: Animals; Behavior, Animal; Brain; Dopamine; Dopamine Agents; Dopamine D2 Receptor Antagonists; Locom | 2012 |