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moclobemide and Obsessive-Compulsive Disorder

moclobemide has been researched along with Obsessive-Compulsive Disorder in 3 studies

Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.

Obsessive-Compulsive Disorder: An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.

Research Excerpts

ExcerptRelevanceReference
"Fluoxetine treatment yielded an enhanced [3H]5-HT release in the three brain areas, but a desensitization of the 5-HT autoreceptor only in the hypothalamus and orbitofrontal cortex."1.30Effect of long-term administration of antidepressant treatments on serotonin release in brain regions involved in obsessive-compulsive disorder. ( Bergqvist, PB; Blier, P; Bouchard, C, 1999)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Joffe, RT1
Bakish, D1
Bergqvist, PB1
Bouchard, C1
Blier, P1
al Jeshi, A1

Trials

1 trial available for moclobemide and Obsessive-Compulsive Disorder

ArticleYear
Combined SSRI-moclobemide treatment of psychiatric illness.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:1

    Topics: 1-Naphthylamine; Adult; Benzamides; Depressive Disorder; Drug Administration Schedule; Drug Therapy,

1994

Other Studies

2 other studies available for moclobemide and Obsessive-Compulsive Disorder

ArticleYear
Effect of long-term administration of antidepressant treatments on serotonin release in brain regions involved in obsessive-compulsive disorder.
    Biological psychiatry, 1999, Jan-15, Volume: 45, Issue:2

    Topics: Animals; Antidepressive Agents; Benzamides; Brain; Electroconvulsive Therapy; Fluoxetine; Guinea Pig

1999
Moclobemide response in obsessive-compulsive disorder.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1999, Volume: 44, Issue:3

    Topics: Adult; Benzamides; Female; Humans; Moclobemide; Monoamine Oxidase Inhibitors; Obsessive-Compulsive D

1999