moclobemide has been researched along with Multiple Sclerosis in 2 studies
Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Excerpt | Relevance | Reference |
|---|---|---|
| " No adverse effects were noted." | 6.69 | Moclobemide treatment in multiple sclerosis patients with comorbid depression: an open-label safety trial. ( Achiron, A; Barak, Y; Ur, E, 1999) |
| " No adverse effects were noted." | 2.69 | Moclobemide treatment in multiple sclerosis patients with comorbid depression: an open-label safety trial. ( Achiron, A; Barak, Y; Ur, E, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Holsboer, F | 1 |
| Grasser, A | 1 |
| Friess, E | 1 |
| Wiedemann, K | 1 |
| Barak, Y | 1 |
| Ur, E | 1 |
| Achiron, A | 1 |
1 review available for moclobemide and Multiple Sclerosis
| Article | Year |
|---|---|
Steroid effects on central neurons and implications for psychiatric and neurological disorders.
Topics: Adrenocorticotropic Hormone; Amitriptyline; Benzamides; Brain; Corticotropin-Releasing Hormone; Dexa | 1994 |
1 trial available for moclobemide and Multiple Sclerosis
| Article | Year |
|---|---|
Moclobemide treatment in multiple sclerosis patients with comorbid depression: an open-label safety trial.
Topics: Adult; Depressive Disorder; Female; Humans; Male; Middle Aged; Moclobemide; Multiple Sclerosis; Pilo | 1999 |