moclobemide has been researched along with Hypotension, Orthostatic in 4 studies
Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.
Hypotension, Orthostatic: A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "From a clinical point of view, orthostatic hypotension is a significant side effect during antidepressant treatment, particularly in the case of tricyclic antidepressants (TCAs)." | 2.71 | Orthostatic side effects of clomipramine and moclobemide during treatment for depression. ( Stage, KB, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stage, KB | 1 |
| Taylor, D | 1 |
| Reveley, A | 1 |
| Faivre, F | 1 |
| Karet, FE | 1 |
| Dickerson, JE | 1 |
| Brown, J | 1 |
| Brown, MJ | 1 |
| Delini-Stula, A | 1 |
| Baier, D | 1 |
| Kohnen, R | 1 |
| Laux, G | 1 |
| Philipp, M | 1 |
| Scholz, HJ | 1 |
2 trials available for moclobemide and Hypotension, Orthostatic
| Article | Year |
|---|---|
Orthostatic side effects of clomipramine and moclobemide during treatment for depression.
Topics: Adult; Aged; Antidepressive Agents; Clomipramine; Depressive Disorder, Major; Drug Administration Sc | 2005 |
Undesirable blood pressure changes under naturalistic treatment with moclobemide, a reversible MAO-A inhibitor--results of the drug utilization observation studies.
Topics: Adult; Aged; Benzamides; Blood Pressure; Cardiovascular Diseases; Comorbidity; Depression; Depressiv | 1999 |
2 other studies available for moclobemide and Hypotension, Orthostatic
| Article | Year |
|---|---|
Clozapine-induced hypotension treated with moclobemide and Bovril.
Topics: Adult; Antipsychotic Agents; Benzamides; Clozapine; Dose-Response Relationship, Drug; Drug Administr | 1995 |
Bovril and moclobemide: a novel therapeutic strategy for central autonomic failure.
Topics: Activities of Daily Living; Autonomic Nervous System Diseases; Benzamides; Blood Pressure; Blood Pre | 1994 |