Page last updated: 2024-10-31

moclobemide and Headache

moclobemide has been researched along with Headache in 7 studies

Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.

Headache: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"An international, multicentre, double blind parallel group study compared the tolerability and efficacy of moclobemide with the selective serotonin reuptake inhibitor (SSRI) fluoxetine for panic disorder."9.09Moclobemide and fluoxetine for panic disorder. International Panic Disorder Study Group. ( Behnke, K; Bouwer, C; Tiller, JW, 1999)
"While on this therapy, 35 of the 42 migraine patients and 16 of the 17 patients with tension-type headache experienced good or very good improvement in their symptoms."5.30[Preventive treatment of migraine and chronic tension headache with moclobemide]. ( Amsler, F; Meienberg, O, 1997)
"An international, multicentre, double blind parallel group study compared the tolerability and efficacy of moclobemide with the selective serotonin reuptake inhibitor (SSRI) fluoxetine for panic disorder."5.09Moclobemide and fluoxetine for panic disorder. International Panic Disorder Study Group. ( Behnke, K; Bouwer, C; Tiller, JW, 1999)
" There were 188 adverse events: insomnia, dizziness, headache, nausea, dry mouth and myoclonic jerks were the most common."2.68Safety and tolerability of combined treatment with moclobemide and SSRIs: a systematic study of 50 patients. ( Hawley, CJ; McPhee, S; Pattinson, HA; Quick, SJ; Ratnam, S, 1996)
"Moclobemide treatment, however, increased the incidence of adverse events elicited by ephedrine, particularly palpitations and headache."2.68Modification of the cardiovascular effects of ephedrine by the reversible monoamine oxidase A-inhibitor moclobemide. ( Dingemanse, J; Gieschke, R; Guentert, T; Stabl, M, 1996)
" A metaregression did not reveal a statistically significant relation between the mean moclobemide dosage for each study and the risk ratio for response rates."2.43A metaanalysis of clinical trials comparing moclobemide with selective serotonin reuptake inhibitors for the treatment of major depressive disorder. ( Fava, M; Papakostas, GI, 2006)
"While on this therapy, 35 of the 42 migraine patients and 16 of the 17 patients with tension-type headache experienced good or very good improvement in their symptoms."1.30[Preventive treatment of migraine and chronic tension headache with moclobemide]. ( Amsler, F; Meienberg, O, 1997)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (85.71)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Papakostas, GI1
Fava, M1
Hawley, CJ1
Quick, SJ1
Ratnam, S1
Pattinson, HA1
McPhee, S1
Versiani, M1
Nardi, AE1
Mundim, FD1
Pinto, S1
Saboya, E1
Kovacs, R1
Dingemanse, J1
Guentert, T1
Gieschke, R1
Stabl, M1
Meienberg, O1
Amsler, F1
Juruena, MF1
Pires, ML1
Calil, HM1
Tiller, JW1
Bouwer, C1
Behnke, K1

Reviews

1 review available for moclobemide and Headache

ArticleYear
A metaanalysis of clinical trials comparing moclobemide with selective serotonin reuptake inhibitors for the treatment of major depressive disorder.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2006, Volume: 51, Issue:12

    Topics: Depressive Disorder, Major; Disorders of Excessive Somnolence; Fatigue; Headache; Humans; Imipramine

2006

Trials

5 trials available for moclobemide and Headache

ArticleYear
Safety and tolerability of combined treatment with moclobemide and SSRIs: a systematic study of 50 patients.
    International clinical psychopharmacology, 1996, Volume: 11, Issue:3

    Topics: Adult; Benzamides; Depressive Disorder; Drug Therapy, Combination; Female; Fluoxetine; Headache; Hum

1996
The long-term treatment of social phobia with moclobemide.
    International clinical psychopharmacology, 1996, Volume: 11 Suppl 3

    Topics: Adolescent; Adult; Benzamides; Female; Headache; Humans; Male; Middle Aged; Moclobemide; Monoamine O

1996
Modification of the cardiovascular effects of ephedrine by the reversible monoamine oxidase A-inhibitor moclobemide.
    Journal of cardiovascular pharmacology, 1996, Volume: 28, Issue:6

    Topics: Adrenergic Agents; Adult; Benzamides; Blood Pressure; Double-Blind Method; Drug Synergism; Ephedrine

1996
Moclobemide effects on prolactin plasma levels in healthy individuals: the hormonal increase induced by a single dose is maintained during a 4-week period of drug intake.
    International clinical psychopharmacology, 1997, Volume: 12, Issue:6

    Topics: Adult; Antidepressive Agents; Benzamides; Euphoria; Headache; Humans; Male; Moclobemide; Monoamine O

1997
Moclobemide and fluoxetine for panic disorder. International Panic Disorder Study Group.
    European archives of psychiatry and clinical neuroscience, 1999, Volume: 249 Suppl 1

    Topics: Adult; Benzamides; Double-Blind Method; Female; Fluoxetine; Headache; Humans; Male; Moclobemide; Mon

1999

Other Studies

1 other study available for moclobemide and Headache

ArticleYear
[Preventive treatment of migraine and chronic tension headache with moclobemide].
    Praxis, 1997, Jul-02, Volume: 86, Issue:27-28

    Topics: Adult; Benzamides; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Headache;

1997