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moclobemide and Dysthymic Disorder

moclobemide has been researched along with Dysthymic Disorder in 6 studies

Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.

Dysthymic Disorder: Chronically depressed mood that occurs for most of the day more days than not for at least 2 years. The required minimum duration in children to make this diagnosis is 1 year. During periods of depressed mood, at least 2 of the following additional symptoms are present: poor appetite or overeating, insomnia or hypersomnia, low energy or fatigue, low self-esteem, poor concentration or difficulty making decisions, and feelings of hopelessness. (DSM-IV)

Research Excerpts

ExcerptRelevanceReference
"The authors compared the outcomes of 35 outpatients with dysthymic disorder randomized to receive either treatment with moclobemide and interpersonal therapy (IPT) or moclobemide and routine clinical management."9.09A randomized controlled trial comparing moclobemide and moclobemide plus interpersonal psychotherapy in the treatment of dysthymic disorder. ( de Mello, MF; Menezes, PR; Myczcowisk, LM, 2001)
"An international, multicenter, placebo-controlled study was undertaken to determine the safety and antidepressant efficacy of moclobemide, a new reversible inhibitor of monoamine oxidase A, and imipramine in the treatment of dysthymia (DSM-III-R)."9.08Moclobemide and imipramine in chronic depression (dysthymia): an international double-blind, placebo-controlled trial. International Collaborative Study Group. ( Amrein, R; Stabl, M; Versiani, M, 1997)
"We report on the case of female patient with chronic dysthymia, who took moclobemide at 300 mg/day throughout her first pregnancy."7.71Moclobemide in pregnancy. ( Rybakowski, JK, 2001)
"The subsequent delineation of dysthymia in DSM-III and its future editions as well as ICD."6.40Pharmacotherapy of dysthymic and chronic depressive disorders: overview with focus on moclobemide. ( Versiani, M, 1998)
"The authors compared the outcomes of 35 outpatients with dysthymic disorder randomized to receive either treatment with moclobemide and interpersonal therapy (IPT) or moclobemide and routine clinical management."5.09A randomized controlled trial comparing moclobemide and moclobemide plus interpersonal psychotherapy in the treatment of dysthymic disorder. ( de Mello, MF; Menezes, PR; Myczcowisk, LM, 2001)
"An international, multicenter, placebo-controlled study was undertaken to determine the safety and antidepressant efficacy of moclobemide, a new reversible inhibitor of monoamine oxidase A, and imipramine in the treatment of dysthymia (DSM-III-R)."5.08Moclobemide and imipramine in chronic depression (dysthymia): an international double-blind, placebo-controlled trial. International Collaborative Study Group. ( Amrein, R; Stabl, M; Versiani, M, 1997)
"We report on the case of female patient with chronic dysthymia, who took moclobemide at 300 mg/day throughout her first pregnancy."3.71Moclobemide in pregnancy. ( Rybakowski, JK, 2001)
"The subsequent delineation of dysthymia in DSM-III and its future editions as well as ICD."2.40Pharmacotherapy of dysthymic and chronic depressive disorders: overview with focus on moclobemide. ( Versiani, M, 1998)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's3 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Versiani, M2
Amrein, R1
Stabl, M1
Montgomery, SA1
Bekaroğlu, M1
Değer, O1
Karahan, SC1
Bilici, M1
Soylu, C1
Orem, A1
de Mello, MF1
Myczcowisk, LM1
Menezes, PR1
Rybakowski, JK1

Reviews

2 reviews available for moclobemide and Dysthymic Disorder

ArticleYear
Pharmacotherapy of dysthymic and chronic depressive disorders: overview with focus on moclobemide.
    Journal of affective disorders, 1998, Volume: 51, Issue:3

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzamides; Clinical Trials as Topic; Comor

1998
Social phobia: diagnosis, severity and implications for treatment.
    European archives of psychiatry and clinical neuroscience, 1999, Volume: 249 Suppl 1

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Behavior Therapy; Benzamides; Benzodiazepines; Child

1999

Trials

2 trials available for moclobemide and Dysthymic Disorder

ArticleYear
Moclobemide and imipramine in chronic depression (dysthymia): an international double-blind, placebo-controlled trial. International Collaborative Study Group.
    International clinical psychopharmacology, 1997, Volume: 12, Issue:4

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzamides; Consti

1997
A randomized controlled trial comparing moclobemide and moclobemide plus interpersonal psychotherapy in the treatment of dysthymic disorder.
    The Journal of psychotherapy practice and research, 2001,Spring, Volume: 10, Issue:2

    Topics: Adult; Antidepressive Agents; Dysthymic Disorder; Female; Humans; Male; Middle Aged; Moclobemide; Pa

2001

Other Studies

2 other studies available for moclobemide and Dysthymic Disorder

ArticleYear
Effects of antidepressant treatments on polymorphonuclear elastase levels in patients with depression.
    Journal of affective disorders, 2000, Volume: 59, Issue:3

    Topics: Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Biomarkers; Depressive Disorder, Maj

2000
Moclobemide in pregnancy.
    Pharmacopsychiatry, 2001, Volume: 34, Issue:2

    Topics: Adult; Dysthymic Disorder; Female; Humans; Moclobemide; Pregnancy; Pregnancy Complications; Pregnanc

2001