moclobemide has been researched along with Drug Overdose in 23 studies
Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The serotonin syndrome is frequently characterized by minor neurologic manifestations that regress rapidly (such as confusion, tremor, ." | 5.30 | Serotonin syndrome due to an overdose of moclobemide and clomipramine. A potentially life-threatening association. ( Desachy, A; François, B; Gastinne, H; Lachatre, G; Marquet, P; Roustan, J, 1997) |
| "Two cases of poisoning with moclobemide are presented." | 3.69 | [Poisoning with a reversible and selective monoaminooxidase inhibitor]. ( Bested, KM; Eriksen, ND; Pall, M, 1997) |
| " In determining the safety profile of a drug, the following strategy is generally employed by a manufacturer: (a) comparison of the drug to placebo in clinical trials to identify the more commonly occurring adverse reactions; (b) comparison of the drug to other known drugs in clinical trials to determine relative frequencies of adverse reactions; (c) examination of reports from practitioners, the so-called spontaneously reported adverse event reports to confirm that what is seen under the experimental conditions of clinical trials is also seen in "real life" and to generate hypotheses about rare adverse reactions to the drug; (d) identification of further adverse reactions from overdose reports; and (e) the conduct of postmarketing studies to further determine drug-drug interactions." | 2.38 | Safety of moclobemide in clinical use. ( Chen, DT; Ruch, R, 1993) |
| "The serotonin syndrome is frequently characterized by minor neurologic manifestations that regress rapidly (such as confusion, tremor, ." | 1.30 | Serotonin syndrome due to an overdose of moclobemide and clomipramine. A potentially life-threatening association. ( Desachy, A; François, B; Gastinne, H; Lachatre, G; Marquet, P; Roustan, J, 1997) |
| "Moclobemide is a recently introduced short-acting, selective and reversible monoamine oxidase inhibitor, type A, with few and mild side-effects at therapeutic doses." | 1.29 | Moclobemide overdose. ( Eriksson, T; Myrenfors, PG; Sandsted, CS; Sjöberg, G, 1993) |
| "Moclobemide is a reversible inhibitor of the monoamine oxidase type A." | 1.28 | Safety of moclobemide taken in overdose for attempted suicide. ( Hetzel, W, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (60.87) | 18.2507 |
| 2000's | 8 (34.78) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Cooper, J | 3 |
| Duffull, SB | 3 |
| Isbister, GK | 5 |
| Kłys, M | 1 |
| Kowalski, P | 1 |
| Rojek, S | 1 |
| Gross, A | 1 |
| Höjer, J | 2 |
| Personne, M | 2 |
| Skagius, AS | 2 |
| Hansson, O | 2 |
| Vuori, E | 2 |
| Henry, JA | 1 |
| Ojanperä, I | 1 |
| Nieminen, R | 1 |
| Savolainen, T | 1 |
| Wahlsten, P | 1 |
| Jäntti, M | 1 |
| Bleumink, GS | 1 |
| van Vliet, AC | 1 |
| van der Tholen, A | 1 |
| Stricker, BH | 1 |
| Hackett, LP | 2 |
| Dawson, AH | 1 |
| Whyte, IM | 2 |
| Smith, AJ | 1 |
| Giroud, C | 1 |
| Horisberger, B | 1 |
| Eap, C | 1 |
| Augsburger, M | 1 |
| Ménétrey, A | 1 |
| Baumann, P | 1 |
| Mangin, P | 1 |
| Downes, MA | 1 |
| Power, BM | 1 |
| Pinder, M | 1 |
| Ilett, KF | 1 |
| Hernandez, AF | 1 |
| Montero, MN | 1 |
| Pla, A | 1 |
| Villanueva, E | 1 |
| Neuvonen, PJ | 1 |
| Pohjola-Sintonen, S | 1 |
| Tacke, U | 1 |
| Gram, LF | 1 |
| Chen, DT | 1 |
| Ruch, R | 1 |
| Myrenfors, PG | 1 |
| Eriksson, T | 1 |
| Sandsted, CS | 1 |
| Sjöberg, G | 1 |
| Iwersen, S | 1 |
| Schmoldt, A | 1 |
| François, B | 1 |
| Marquet, P | 1 |
| Desachy, A | 1 |
| Roustan, J | 1 |
| Lachatre, G | 1 |
| Gastinne, H | 1 |
| Pall, M | 1 |
| Bested, KM | 1 |
| Eriksen, ND | 1 |
| Singer, PP | 1 |
| Jones, GR | 1 |
| Ferrer-Dufol, A | 1 |
| Perez-Aradros, C | 1 |
| Murillo, EC | 1 |
| Marques-Alamo, JM | 1 |
| Roxanas, MG | 1 |
| Machado, JF | 1 |
| FitzSimmons, CR | 1 |
| Metha, S | 1 |
| Hetzel, W | 1 |
1 review available for moclobemide and Drug Overdose
| Article | Year |
|---|---|
Safety of moclobemide in clinical use.
Topics: Antidepressive Agents; Benzamides; Clinical Trials as Topic; Drug Overdose; Humans; Moclobemide; Mon | 1993 |
22 other studies available for moclobemide and Drug Overdose
| Article | Year |
|---|---|
Predicting serotonin toxicity in serotonin reuptake inhibitor overdose.
Topics: Adult; Drug Overdose; Female; Humans; Male; Moclobemide; Olanzapine; Retrospective Studies; Risperid | 2023 |
Predicting serotonin toxicity in serotonin reuptake inhibitor overdose.
Topics: Adult; Drug Overdose; Female; Humans; Male; Moclobemide; Olanzapine; Retrospective Studies; Risperid | 2023 |
Predicting serotonin toxicity in serotonin reuptake inhibitor overdose.
Topics: Adult; Drug Overdose; Female; Humans; Male; Moclobemide; Olanzapine; Retrospective Studies; Risperid | 2023 |
Predicting serotonin toxicity in serotonin reuptake inhibitor overdose.
Topics: Adult; Drug Overdose; Female; Humans; Male; Moclobemide; Olanzapine; Retrospective Studies; Risperid | 2023 |
Death of a female cocaine user due to the serotonin syndrome following moclobemide-venlafaxine overdose.
Topics: Cocaine; Cocaine-Related Disorders; Cyclohexanols; Dopamine Uptake Inhibitors; Drug Overdose; Female | 2009 |
[Serotonin syndrome--several cases of this often overlooked diagnosis].
Topics: Adult; Antidepressive Agents; Diagnosis, Differential; Drug Overdose; Female; Humans; Male; Moclobem | 2002 |
Death following ingestion of MDMA (ecstasy) and moclobemide.
Topics: Adolescent; Adult; Drug Interactions; Drug Overdose; Fatal Outcome; Female; Hallucinogens; Humans; M | 2003 |
Fatal combination of moclobemide overdose and whisky.
Topics: Adult; Alcohol Drinking; Antidepressive Agents; Drug Overdose; Fatal Outcome; Humans; Male; Moclobem | 2003 |
Moclobemide poisoning: toxicokinetics and occurrence of serotonin toxicity.
Topics: Adult; Antidepressive Agents; Cohort Studies; Critical Care; Drug Combinations; Drug Interactions; D | 2003 |
Death following acute poisoning by moclobemide.
Topics: Antidepressive Agents; Benzodiazepines; Central Nervous System Depressants; Drug Overdose; Ethanol; | 2004 |
QTc abnormalities in deliberate self-poisoning with moclobemide.
Topics: Adult; Antidepressive Agents; Drug Overdose; Electrocardiography; Female; Heart Conduction System; H | 2005 |
Fatal serotonin syndrome following a combined overdose of moclobemide, clomipramine and fluoxetine.
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricy | 1995 |
Fatal moclobemide overdose or death caused by serotonin syndrome?
Topics: Adult; Antidepressive Agents; Benzamides; Cause of Death; Clomipramine; Drug Interactions; Drug Over | 1995 |
Five fatal cases of serotonin syndrome after moclobemide-citalopram or moclobemide-clomipramine overdoses.
Topics: Adult; Benzamides; Citalopram; Clomipramine; Drug Interactions; Drug Overdose; Fatal Outcome; Female | 1993 |
[Antidepressive drug therapy, suicidal tendency and suicide, 2 cases reported in connection with moclobemide (Aurorix) therapy].
Topics: Aged; Antidepressive Agents; Benzamides; Bipolar Disorder; Drug Overdose; Female; Humans; Male; Midd | 1994 |
Moclobemide overdose.
Topics: Adult; Benzamides; Drug Overdose; Drug Synergism; Female; Humans; Male; Middle Aged; Moclobemide; Mo | 1993 |
Three suicide attempts with moclobemide.
Topics: Antidepressive Agents, Tricyclic; Benzamides; Clomipramine; Drug Interactions; Drug Overdose; Female | 1996 |
Serotonin syndrome due to an overdose of moclobemide and clomipramine. A potentially life-threatening association.
Topics: Antidepressive Agents; Benzamides; Clomipramine; Drug Interactions; Drug Overdose; Female; Humans; M | 1997 |
[Poisoning with a reversible and selective monoaminooxidase inhibitor].
Topics: Adult; Antidepressive Agents; Benzamides; Critical Care; Drug Overdose; Female; Humans; Moclobemide; | 1997 |
An uncommon fatality due to moclobemide and paroxetine.
Topics: Adult; Antidepressive Agents, Second-Generation; Benzamides; Drug Overdose; Fatal Outcome; Gas Chrom | 1997 |
Fatal serotonin syndrome caused by moclobemide-clomipramine overdose.
Topics: Adult; Benzamides; Clomipramine; Clorazepate Dipotassium; Drug Interactions; Drug Overdose; Fatal Ou | 1998 |
Serotonin syndrome in combined moclobemide and venlafaxine ingestion.
Topics: Adult; Benzamides; Central Nervous System Depressants; Cyclohexanols; Drug Interactions; Drug Overdo | 1998 |
Serotonin syndrome caused by overdose with paroxetine and moclobemide.
Topics: Adult; Benzamides; Disease-Free Survival; Drug Overdose; Emergency Treatment; Humans; Male; Moclobem | 1999 |
[Serotonin syndrome. Several cases of this often overlooked diagnosis].
Topics: Adult; Antidepressive Agents; Diagnosis, Differential; Drug Overdose; Female; Humans; Male; Moclobem | 2002 |
Safety of moclobemide taken in overdose for attempted suicide.
Topics: Adult; Aged; Benzamides; Drug Overdose; Female; Humans; Male; Middle Aged; Moclobemide; Monoamine Ox | 1992 |