Page last updated: 2024-10-31

moclobemide and Cognition Disorders

moclobemide has been researched along with Cognition Disorders in 6 studies

Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"The new reversible MAOl moclobemide was compared with placebo in the treatment of elderly patients with DSM-III diagnosis of dementia and/or of major depression."5.08Moclobemide in elderly patients with cognitive decline and depression: an international double-blind, placebo-controlled trial. ( Amrein, R; Mountjoy, CQ; Roth, M, 1996)
" While clinical aspects will be presented in a subsequent review, this article focuses primarily on moclobemide's evolution, pharmacodynamic and pharmacokinetic properties."2.41Moclobemide: evolution, pharmacodynamic, and pharmacokinetic properties. ( Bonnet, U, 2002)
"Depression is a highly prevalent concomitant of dementia."2.40Depression and dementia: comorbidities, identification, and treatment. ( Meyers, BS, 1998)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (83.33)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bonnet, U1
Galderisi, S1
Mucci, A1
Bucci, P1
Mignone, ML1
Maj, M1
Roth, M1
Mountjoy, CQ1
Amrein, R2
Meyers, BS1
Martin, JR1
Cameron, AM1
Anand, R1
Wesnes, KA1

Reviews

3 reviews available for moclobemide and Cognition Disorders

ArticleYear
Moclobemide: evolution, pharmacodynamic, and pharmacokinetic properties.
    CNS drug reviews, 2002,Fall, Volume: 8, Issue:3

    Topics: Animals; Antidepressive Agents; Anxiety; Cognition Disorders; Depression; Disease Models, Animal; Dr

2002
Depression and dementia: comorbidities, identification, and treatment.
    Journal of geriatric psychiatry and neurology, 1998,Winter, Volume: 11, Issue:4

    Topics: Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Benzamides; Citalopram; Clomipramine; Cog

1998
Moclobemide in patients with dementia and depression.
    Advances in neurology, 1999, Volume: 80

    Topics: Animals; Benzamides; Cognition Disorders; Dementia; Depression; Humans; Moclobemide; Monoamine Oxida

1999

Trials

1 trial available for moclobemide and Cognition Disorders

ArticleYear
Moclobemide in elderly patients with cognitive decline and depression: an international double-blind, placebo-controlled trial.
    The British journal of psychiatry : the journal of mental science, 1996, Volume: 168, Issue:2

    Topics: Aged; Aged, 80 and over; Antidepressive Agents; Benzamides; Cognition Disorders; Comorbidity; Dement

1996

Other Studies

2 other studies available for moclobemide and Cognition Disorders

ArticleYear
Influence of moclobemide on cognitive functions of nine depressed patients: pilot trial with neurophysiological and neuropsychological indices.
    Neuropsychobiology, 1996, Volume: 33, Issue:1

    Topics: Adult; Antidepressive Agents; Arousal; Attention; Benzamides; Cognition Disorders; Depressive Disord

1996
Cognition-enhancing effects of moclobemide, a reversible MAO inhibitor, in humans.
    Advances in neurology, 1990, Volume: 51

    Topics: Benzamides; Cognition Disorders; Double-Blind Method; Humans; Moclobemide; Monoamine Oxidase Inhibit

1990