moclobemide has been researched along with Bipolar Disorder in 14 studies
Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Moclobemide proved to be a well-tolerated and effective antidepressant, with both groups showing improvement." | 2.66 | A clinical study of the selective MAO-A-inhibitor moclobemide (Ro 11-1163): a comparison of 2 different dosages with particular reference to platelet MAO-activity and urinary MHPG-excretion. ( Böning, J; Fuchs, G; Lensch, K; Milech, U, 1987) |
| "treated with Moclobemide and from 36." | 2.65 | A placebo-controlled study of the antidepressant activity of moclobemide, a new MAO-A inhibitor. ( Barba, C; Carolei, A; Casacchia, M; Frontoni, M; Meco, G; Rossi, A; Zylberman, MR, 1984) |
| "1." | 1.29 | Moclobemide (Aurorix) in primary major depression. ( Barsi, J; Gábor, A; György, S; Rihmer, Z; Vad, G; Vég, K; Zalay, B, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jonsson, BH | 1 |
| Eli, R | 1 |
| Fasciano, J | 1 |
| Casacchia, M | 1 |
| Carolei, A | 1 |
| Barba, C | 1 |
| Frontoni, M | 1 |
| Rossi, A | 1 |
| Meco, G | 1 |
| Zylberman, MR | 1 |
| Stefanis, CN | 1 |
| Alevizos, BH | 1 |
| Papadimitriou, GN | 1 |
| Markianos, M | 1 |
| Alevizos, B | 1 |
| Hatzimanolis, J | 1 |
| Stefanis, C | 1 |
| Gram, LF | 1 |
| Rihmer, Z | 1 |
| Barsi, J | 1 |
| Vad, G | 1 |
| György, S | 1 |
| Zalay, B | 1 |
| Vég, K | 1 |
| Gábor, A | 1 |
| Calabrese, JR | 1 |
| Rapport, DJ | 1 |
| Kimmel, SE | 1 |
| Shelton, MD | 1 |
| Silverstone, T | 1 |
| Ucha Udabe, R | 1 |
| Márquez, CA | 2 |
| Traballi, CA | 1 |
| Portes, N | 1 |
| Monti, JM | 1 |
| Baumhackl, U | 1 |
| Bizière, K | 1 |
| Fischbach, R | 1 |
| Geretsegger, C | 1 |
| Hebenstreit, G | 1 |
| Radmayr, E | 1 |
| Stabl, M | 1 |
| Versiani, M | 1 |
| Oggero, U | 1 |
| Alterwain, P | 1 |
| Capponi, R | 1 |
| Dajas, F | 1 |
| Heinze-Martin, G | 1 |
| Poleo, MA | 1 |
| Rivero-Almanzor, LE | 1 |
| Rossel, L | 1 |
| Lensch, K | 1 |
| Fuchs, G | 1 |
| Böning, J | 1 |
| Milech, U | 1 |
1 review available for moclobemide and Bipolar Disorder
| Article | Year |
|---|---|
Controlled trials in bipolar I depression: focus on switch rates and efficacy.
Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Antimanic Agents; Bipolar Disorder; Control | 1999 |
7 trials available for moclobemide and Bipolar Disorder
| Article | Year |
|---|---|
A placebo-controlled study of the antidepressant activity of moclobemide, a new MAO-A inhibitor.
Topics: Adult; Antidepressive Agents; Benzamides; Bipolar Disorder; Clinical Trials as Topic; Depressive Dis | 1984 |
Antidepressant effect of Ro 11-1163, a new MAO inhibitor.
Topics: Adult; Benzamides; Bipolar Disorder; Clinical Trials as Topic; Depressive Disorder; Female; Humans; | 1982 |
Moclobemide vs. imipramine in bipolar depression: a multicentre double-blind clinical trial.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Mi | 2001 |
Double-blind comparison of moclobemide, imipramine and placebo in depressive patients.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Benzamides; Bipolar Disorder; Depressive Disorder; D | 1990 |
Efficacy and tolerability of moclobemide compared with imipramine in depressive disorder (DSM-III): an Austrian double-blind, multicentre study.
Topics: Adjustment Disorders; Adult; Aged; Aged, 80 and over; Austria; Benzamides; Bipolar Disorder; Depress | 1989 |
A double-blind comparative trial of moclobemide v. imipramine and placebo in major depressive episodes.
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Benzamides; Bipolar Disorder; Depressive Disorder; Do | 1989 |
A clinical study of the selective MAO-A-inhibitor moclobemide (Ro 11-1163): a comparison of 2 different dosages with particular reference to platelet MAO-activity and urinary MHPG-excretion.
Topics: Adult; Aged; Benzamides; Bipolar Disorder; Blood Platelets; Blood Pressure; Clinical Trials as Topic | 1987 |
6 other studies available for moclobemide and Bipolar Disorder
| Article | Year |
|---|---|
Nicotinic Acid Long-Term Effectiveness in a Patient with Bipolar Type II Disorder: A Case of Vitamin Dependency.
Topics: Aged; Anticonvulsants; Antidepressive Agents; Bipolar Disorder; Depression; Dose-Response Relationsh | 2018 |
A chronopharmacological diagnostic test and treatment for bipolar disorder and depression: nitric oxide release during sleep causes it to become depressogenic in a subset of patients.
Topics: Age Factors; Bipolar Disorder; Brain; Humans; Melatonin; Moclobemide; Nitric Oxide; Polymorphism, Ge | 2006 |
Effects of monoamine oxidase A inhibition on plasma biogenic amine metabolites in depressed patients.
Topics: Adult; Arousal; Benzamides; Biogenic Amines; Bipolar Disorder; Chromatography, High Pressure Liquid; | 1994 |
[Antidepressive drug therapy, suicidal tendency and suicide, 2 cases reported in connection with moclobemide (Aurorix) therapy].
Topics: Aged; Antidepressive Agents; Benzamides; Bipolar Disorder; Drug Overdose; Female; Humans; Male; Midd | 1994 |
Moclobemide (Aurorix) in primary major depression.
Topics: Adult; Aged; Benzamides; Biomarkers; Bipolar Disorder; Depressive Disorder; Dexamethasone; Female; H | 1994 |
Effect of a reversible monoamine oxidase-A inhibitor (moclobemide) on sleep of depressed patients.
Topics: Adult; Benzamides; Bipolar Disorder; Depressive Disorder; Electroencephalography; Evoked Potentials; | 1989 |