Page last updated: 2024-10-31

moclobemide and Anxiety

moclobemide has been researched along with Anxiety in 12 studies

Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"The anxiolytic effects of aniracetam have not been proven in animals despite its clinical usefulness for post-stroke anxiety."7.71Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. ( Kurasawa, M; Nakamura, K, 2001)
"Moclobemide is a reversible selective inhibitor of monoamine oxidase A."6.68Moclobemide for anxiety disorders: a focus on moclobemide for panic disorder. ( Behnke, K; Bouwer, C; Tiller, JW, 1997)
"The anxiolytic effects of aniracetam have not been proven in animals despite its clinical usefulness for post-stroke anxiety."3.71Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. ( Kurasawa, M; Nakamura, K, 2001)
"Moclobemide was superior for the reduction of the subjective general anxiety (BAI) during the first 3 months of treatment, but its influence on avoidant behavior (LSAS avoidance subscale) was less pronounced."2.72Moclobemide and cognitive behavioral therapy in the treatment of social phobia. A six-month controlled study and 24 months follow up. ( Dockery, C; Horácek, J; Höschl, C; Houbová, P; Klaschka, J; Kosová, J; Pasková, B; Prasko, J; Praskova, H; Seifertová, D; Záleský, R, 2006)
" The efficacies between the two dosing regimens as determined by the HAM-D score and from the CGI were found not to differ significantly."2.68A comparison of the efficacy and tolerability of moclobemide given as a single daily dose or in three divided doses per day for the treatment of patients with a major depressive episode (DSM-III-R) ( Caracatsanis, A; Collier, J; Collins, C; Cramer, D; Edwards, R; Fox, K; Newburn, G; Reeves, J; Thomas, H, 1995)
"Moclobemide is a reversible selective inhibitor of monoamine oxidase A."2.68Moclobemide for anxiety disorders: a focus on moclobemide for panic disorder. ( Behnke, K; Bouwer, C; Tiller, JW, 1997)
" Side effects were assessed through the Dosage Record Emergent Symptoms at days 0, 7, 14, 30, 45, and 60."2.67Effects of moclobemide on depressive symptoms and cognitive performance in a geriatric population: a controlled comparative study versus imipramine. ( Delle Chiaie, R; Donnini, M; Gambino, C; Pancheri, P; Seripa, S; Trillo, L; Vicario, E, 1994)
" While clinical aspects will be presented in a subsequent review, this article focuses primarily on moclobemide's evolution, pharmacodynamic and pharmacokinetic properties."2.41Moclobemide: evolution, pharmacodynamic, and pharmacokinetic properties. ( Bonnet, U, 2002)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (58.33)18.2507
2000's5 (41.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pekiner, FN1
Gumru, B1
Ozbayrak, S1
Bonnet, U1
Prasko, J1
Dockery, C1
Horácek, J1
Houbová, P1
Kosová, J1
Klaschka, J1
Pasková, B1
Praskova, H1
Seifertová, D1
Záleský, R1
Höschl, C1
Koval'chuk, VV1
Newburn, G1
Edwards, R1
Thomas, H1
Collier, J1
Fox, K1
Collins, C1
Cramer, D1
Reeves, J1
Caracatsanis, A1
Pancheri, P1
Delle Chiaie, R1
Donnini, M1
Seripa, S1
Gambino, C1
Vicario, E1
Trillo, L1
Griebel, G1
Perrault, G1
Sanger, DJ1
Tiller, JW1
Bouwer, C1
Behnke, K1
Eroğlu, L1
Güven, O1
Iakovlev, VA1
Nakamura, K1
Kurasawa, M1

Reviews

1 review available for moclobemide and Anxiety

ArticleYear
Moclobemide: evolution, pharmacodynamic, and pharmacokinetic properties.
    CNS drug reviews, 2002,Fall, Volume: 8, Issue:3

    Topics: Animals; Antidepressive Agents; Anxiety; Cognition Disorders; Depression; Disease Models, Animal; Dr

2002

Trials

6 trials available for moclobemide and Anxiety

ArticleYear
Efficacy of moclobemide in burning mouth syndrome: a nonrandomized, open-label study.
    Journal of orofacial pain, 2008,Spring, Volume: 22, Issue:2

    Topics: Analysis of Variance; Antidepressive Agents; Anxiety; Burning Mouth Syndrome; Case-Control Studies;

2008
Moclobemide and cognitive behavioral therapy in the treatment of social phobia. A six-month controlled study and 24 months follow up.
    Neuro endocrinology letters, 2006, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Anxiety; Cognitive Behavioral Therapy; Combined Modality Therapy; Female; Follow-

2006
[Pharmacologic correction of psycho-emotive disorders in the rehabilitation of patients after removal of brain tumors].
    Voprosy onkologii, 2007, Volume: 53, Issue:6

    Topics: Adult; Alprazolam; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Brain Neoplas

2007
A comparison of the efficacy and tolerability of moclobemide given as a single daily dose or in three divided doses per day for the treatment of patients with a major depressive episode (DSM-III-R)
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:4 Suppl 2

    Topics: Adult; Antidepressive Agents; Anxiety; Benzamides; Depressive Disorder; Double-Blind Method; Female;

1995
Effects of moclobemide on depressive symptoms and cognitive performance in a geriatric population: a controlled comparative study versus imipramine.
    Clinical neuropharmacology, 1994, Volume: 17 Suppl 1

    Topics: Aged; Antidepressive Agents; Anxiety; Benzamides; Cognition; Depressive Disorder; Double-Blind Metho

1994
Moclobemide for anxiety disorders: a focus on moclobemide for panic disorder.
    International clinical psychopharmacology, 1997, Volume: 12 Suppl 6

    Topics: Adult; Anxiety; Benzamides; Blood Pressure; Female; Fluoxetine; Humans; Male; Moclobemide; Monoamine

1997

Other Studies

5 other studies available for moclobemide and Anxiety

ArticleYear
Behavioural profiles of the reversible monoamine-oxidase-A inhibitors befloxatone and moclobemide in an experimental model for screening anxiolytic and anti-panic drugs.
    Psychopharmacology, 1997, Volume: 131, Issue:2

    Topics: Animals; Anxiety; Avoidance Learning; Benzamides; Disease Models, Animal; Dose-Response Relationship

1997
The effects of moclobemide on the yohimbine-induced anxiogenic action in the elevated plus-maze.
    Pharmacological research, 1998, Volume: 37, Issue:2

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Anti-Anxiety Agents;

1998
[Aurorix--an antidepressant with a wide spectrum of action].
    Voenno-meditsinskii zhurnal, 1998, Volume: 319, Issue:4

    Topics: Antidepressive Agents; Anxiety; Benzamides; Contraindications; Depression; Dose-Response Relationshi

1998
[Various forms of risk factors of antidepressive agents for influencing sexual functions. Moclobemid is first choice for the therapy of sexually active patients with depression].
    Fortschritte der Neurologie-Psychiatrie, 1999, Volume: 67, Issue:5 Suppl Un

    Topics: Antidepressive Agents; Anxiety; Benzamides; Depression; Depressive Disorder; Female; Humans; Male; M

1999
Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism.
    European journal of pharmacology, 2001, May-18, Volume: 420, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Bro

2001