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moclobemide and Acute Post-Traumatic Stress Disorder

moclobemide has been researched along with Acute Post-Traumatic Stress Disorder in 5 studies

Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
moclobemide : A member of the class of benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression.

Research Excerpts

ExcerptRelevanceReference
"Moclobemide, which is a reversible inhibitor of monoamine oxidase-A, is relatively free of these limitations and is therefore potentially useful in the treatment of post-traumatic stress disorder."2.68An open trial of moclobemide in the treatment of post-traumatic stress disorder. ( Fox, C; Neal, LA; Shapland, W, 1997)
"Post-traumatic stress disorder (PTSD) is a long-lasting mental disorder and accompanied by worse fear extinction."1.56Administration of moclobemide facilitates fear extinction and attenuates anxiety-like behaviors by regulating synaptic-associated proteins in a rat model of post-traumatic stress disorder. ( Han, F; Shi, Y; Xiao, B, 2020)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Xiao, B1
Han, F1
Shi, Y1
Onder, E1
Tural, U1
Aker, T1
Holsboer, F1
Grasser, A1
Friess, E1
Wiedemann, K1
Neal, LA1
Shapland, W1
Fox, C1
Liebowitz, MR1
Hollander, E1
Schneier, F1
Campeas, R1
Welkowitz, L1
Hatterer, J1
Fallon, B1

Reviews

2 reviews available for moclobemide and Acute Post-Traumatic Stress Disorder

ArticleYear
Steroid effects on central neurons and implications for psychiatric and neurological disorders.
    Annals of the New York Academy of Sciences, 1994, Nov-30, Volume: 746

    Topics: Adrenocorticotropic Hormone; Amitriptyline; Benzamides; Brain; Corticotropin-Releasing Hormone; Dexa

1994
Reversible and irreversible monoamine oxidase inhibitors in other psychiatric disorders.
    Acta psychiatrica Scandinavica. Supplementum, 1990, Volume: 360

    Topics: Antidepressive Agents; Benzamides; Borderline Personality Disorder; Bulimia; Combined Modality Thera

1990

Trials

2 trials available for moclobemide and Acute Post-Traumatic Stress Disorder

ArticleYear
A comparative study of fluoxetine, moclobemide, and tianeptine in the treatment of posttraumatic stress disorder following an earthquake.
    European psychiatry : the journal of the Association of European Psychiatrists, 2006, Volume: 21, Issue:3

    Topics: Adult; Analysis of Variance; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antide

2006
An open trial of moclobemide in the treatment of post-traumatic stress disorder.
    International clinical psychopharmacology, 1997, Volume: 12, Issue:4

    Topics: Adult; Antidepressive Agents; Benzamides; Female; Humans; Male; Middle Aged; Moclobemide; Monoamine

1997

Other Studies

1 other study available for moclobemide and Acute Post-Traumatic Stress Disorder

ArticleYear
Administration of moclobemide facilitates fear extinction and attenuates anxiety-like behaviors by regulating synaptic-associated proteins in a rat model of post-traumatic stress disorder.
    Synapse (New York, N.Y.), 2020, Volume: 74, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Disks Large Homolog 4 Protein; Extinction, Psychological; Fear; Limbic

2020