mocetinostat has been researched along with Communicable-Diseases* in 5 studies
2 review(s) available for mocetinostat and Communicable-Diseases
| Article | Year |
|---|---|
The Pathophysiological Role of Neutrophil Extracellular Traps in Inflammatory Diseases.
Topics: Animals; Autoantigens; Autoimmunity; Biomarkers; Cardiovascular Diseases; Chromatin; Citrullination; Citrulline; Communicable Diseases; Disease Models, Animal; Extracellular Traps; Histones; Humans; Hydrolases; Inflammation; Metabolic Diseases; Neoplasms; Peroxidase; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Risk Factors; Serine Proteases | 2018 |
Role of oxidative stress in infectious diseases. A review.
Oxidative stress plays a dual role in infections. Free radicals protect against invading microorganisms, and they can also cause tissue damage during the resulting inflammation. In the process of infection, there is generation of reactive species by myeloperoxidase, NADPH oxidase, and nitric oxide synthase. On the other hand, reactive species can be generated among others, by cytochrome P450, some metals, and xanthine oxidase. Some pathologies arising during infection can be attributed to oxidative stress and generation of reactive species in infection can even have fatal consequences. This article reviews the basic pathways in which reactive species can accumulate during infectious diseases and discusses the related health consequences. Topics: Communicable Diseases; Cytochrome P-450 Enzyme System; Free Radicals; Humans; Metabolic Networks and Pathways; Metals; NADPH Oxidases; Nitric Oxide Synthase; Oxidative Stress; Peroxidase; Xanthine Oxidase | 2013 |
3 other study(ies) available for mocetinostat and Communicable-Diseases
| Article | Year |
|---|---|
Influenza Virus Infection Increases Host Susceptibility To Secondary Infection with Pseudomonas aeruginosa, and This Is Attributed To Neutrophil Dysfunction through Reduced Myeloperoxidase Activity.
Topics: Coinfection; Communicable Diseases; Humans; Influenza, Human; Lung; Neutrophils; Orthomyxoviridae; Orthomyxoviridae Infections; Peroxidase; Pseudomonas aeruginosa; Pseudomonas Infections | 2023 |
Impairment of the oxygen-dependent microbicidal mechanisms of polymorphonuclear neutrophils in patients with type 2 diabetes is not associated with increased susceptibility to infection.
Phagocytosis, bactericidal capacity and some selected parameters of oxygen-dependent bactericidal mechanisms were evaluated in 20 patients with type 2 diabetes being in similar (intermediate) state of metabolic control and in 15 healthy individuals. Polymorphonuclear neutrophils (PMNs) from diabetics showed normal ability to phagocytose staphylococci, a decreased Intracellular bacteria killing, the impaired stimulated superoxide anion (O2-) and hydrogen peroxide (H2O2) production and the low intracellular myeloperoxidase activity. The obtained data seem to indicate that the decreased bacterial killing by PMNs isolated from diabetics are partly at least related to an impairment of the oxygen-dependent bactericidal mechanisms. Since none of the diabetic patients suffered from recurrent infection the clinical significance of our finding is still uncertain. Topics: Adult; Aged; Communicable Diseases; Diabetes Mellitus, Type 2; Disease Susceptibility; Female; Humans; Hydrogen Peroxide; Male; Middle Aged; Neutrophils; Peroxidase; Phagocytosis; Reference Values; Staphylococcus aureus; Superoxides | 1993 |
[ON CHANGES IN LEUKOCYTE OXIDO-PEROXIDASE ENZYME ACTIVITY IN INFECTIOUS DISEASES].
Topics: Abscess; Animals; Bronchopneumonia; Brucellosis; Cellulitis; Clinical Enzyme Tests; Communicable Diseases; Furunculosis; Herpes Zoster; Humans; Infections; Influenza, Human; Leukocytes; Oxidoreductases; Peroxidase; Peroxidases; Pneumonia; Pyoderma; Tinea | 1963 |