mobiflex and Skin-Neoplasms

The aim of the study was to investigate if there was an association between intraoperative NSAID use and recurrence or survival. A cohort of patients who underwent sentinel lymph node biopsy for the treatment of cutaneous melanoma was retrospectively recruited. After applying inclusion and exclusion criteria, 516 were included (NSAIDs = 307). The 10-year melanoma-specific survival was 63.2%. Log-rank test showed no statistically significant differences in time to treatment failure, melanoma-specific survival, disease-free survival, and overall survival between the study groups. The current study did not support the use of intraoperative NSAIDs in preventing death or recurrence in patients with melanoma.

Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Female; Humans; Isoxazoles; Kaplan-Meier Estimate; Ketorolac; Male; Melanoma; Melanoma, Cutaneous Malignant; Middle Aged; Neoplasm Recurrence, Local; Perioperative Period; Piroxicam; Retrospective Studies; Sentinel Lymph Node Biopsy; Skin Neoplasms; Treatment Outcome