mna-715 has been researched along with Diabetes-Mellitus--Type-1* in 2 studies
2 other study(ies) available for mna-715 and Diabetes-Mellitus--Type-1
Article | Year |
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Leflunomide and its analogue X920715 synergize with cyclosporin A in preventing early graft failure and delaying graft rejection of xenogeneic islets in nonobese diabetic mice.
Topics: Alkynes; Animals; Cyclosporine; Diabetes Mellitus, Type 1; Drug Synergism; Graft Rejection; Immunosuppressive Agents; Islets of Langerhans Transplantation; Isoxazoles; Leflunomide; Mice; Mice, Inbred NOD; Nitriles; Rats; Transplantation, Heterologous | 2001 |
Generation of O2- radicals in macrophages can be inhibited in vitro and in vivo by derivatives of leflunomide's primary metabolite.
Topics: Acrylamides; Alkynes; Animals; Caproates; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Free Radicals; Humans; Immunosuppressive Agents; Isoxazoles; Macrophages; Mice; Mice, Inbred NOD; Nitriles; Superoxides | 1999 |