mln-9708 and Multiple-Myeloma

mln-9708 has been researched along with Multiple-Myeloma* in 1 studies

Other Studies

1 other study(ies) available for mln-9708 and Multiple-Myeloma

Article	Year
Design, synthesis, in vitro and in vivo evaluation, and structure-activity relationship (SAR) discussion of novel dipeptidyl boronic acid proteasome inhibitors as orally available anti-cancer agents for the treatment of multiple myeloma and mechanism stud Bioorganic & medicinal chemistry, 2018, 08-07, Volume: 26, Issue:14 A series of novel dipeptidyl boronic acid inhibitors of 20S proteasome were designed and synthesized. Aliphatic groups at R Topics: Administration, Oral; Animals; Antineoplastic Agents; Boronic Acids; Cell Cycle; Cell Proliferation; Dipeptides; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Nude; Microsomes, Liver; Molecular Structure; Multiple Myeloma; Neoplasms, Experimental; Proteasome Inhibitors; Structure-Activity Relationship; Tumor Cells, Cultured	2018

Article

Year

Design, synthesis, in vitro and in vivo evaluation, and structure-activity relationship (SAR) discussion of novel dipeptidyl boronic acid proteasome inhibitors as orally available anti-cancer agents for the treatment of multiple myeloma and mechanism stud

Bioorganic & medicinal chemistry, 2018, 08-07, Volume: 26, Issue:14

A series of novel dipeptidyl boronic acid inhibitors of 20S proteasome were designed and synthesized. Aliphatic groups at R

Topics: Administration, Oral; Animals; Antineoplastic Agents; Boronic Acids; Cell Cycle; Cell Proliferation; Dipeptides; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Nude; Microsomes, Liver; Molecular Structure; Multiple Myeloma; Neoplasms, Experimental; Proteasome Inhibitors; Structure-Activity Relationship; Tumor Cells, Cultured

2018