ml276 and Neoplasms

ml276 has been researched along with Neoplasms* in 1 studies

Reviews

1 review(s) available for ml276 and Neoplasms

ArticleYear
Boosting the Discovery of Small Molecule Inhibitors of Glucose-6-Phosphate Dehydrogenase for the Treatment of Cancer, Infectious Diseases, and Inflammation.
    Journal of medicinal chemistry, 2022, 03-24, Volume: 65, Issue:6

    We present an overview of small molecule glucose-6-phosphate dehydrogenase (G6PD) inhibitors that have potential for use in the treatment of cancer, infectious diseases, and inflammation. Both steroidal and nonsteroidal inhibitors have been identified with steroidal inhibitors lacking target selectivity. The main scaffolds encountered in nonsteroidal inhibitors are quinazolinones and benzothiazinones/benzothiazepinones. Three molecules show promise for development as antiparasitic (

    Topics: Communicable Diseases; Drug Discovery; Glucosephosphate Dehydrogenase; High-Throughput Screening Assays; Humans; Inflammation; Neoplasms

2022