ml 7 and Disease Models, Animal

ml 7 has been researched along with Disease Models, Animal in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (18.75)29.6817
2010's10 (62.50)24.3611
2020's3 (18.75)2.80

Authors

AuthorsStudies
Beaver, Y; Borchardt, AJ; Cayanan, CS; Clark, AF; Cook, TG; Cramp, J; Davis, RL; Gardiner, EM; Hellberg, MR; Kahraman, M; McLaughlin, MA; Noble, SA; Prins, TJ; Shiau, AK1
Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Abreu, MT; Banerjee, S; Erhart, FN; Meng, J; Olson, RK; Ramakrishnan, S; Roy, S; Saluja, AK; Segura, B; Sharma, M; Sharma, U; Zhang, L1
Ding, J; Ding, Y; Gui, S; Li, L; Li, Z; Meng, S; Wang, D; Wang, Y; Wei, W; Zhou, Q; Zhu, H1
Gong, X; Huang, C; Liu, J; Wang, L; Zhang, C; Zhang, Z1
Ait-Belgnaoui, A; Braniste, V; Gabanou, M; Houdeau, E; Martin, PG; Moussaoui, N; Olier, M; Sekkal, S; Théodorou, V1
Li, TB; Liu, B; Lou, Z; Luo, XJ; Ma, QL; Peng, J; Peng, JJ; Zhang, HF; Zhang, JJ; Zhang, XJ1
Chi, Y; He, X; Li, J; Li, M; Liu, Y; Pan, X; Zhang, Q; Zhang, Y1
Cheng, X; Wan, Y; Wang, X; Wang, Y; Zhou, Q; Zhu, H1
Bai, JW; Deng, WW; Xu, SM; Zhang, DX; Zhang, J1
Boyer, L; Buchan, AM; Conlin, VS; Dai, C; Jacobson, K; Nguyen, C; Vallance, BA; Wu, X1
Ackermann, B; Behl, C; Engelhard, K; Kuhlmann, CR; Luh, C; Luhmann, HJ; Thal, SC; Timaru-Kast, R; Werner, C1
Han, D; Nakao, A; Ouyang, Y; Zhang, L1
Al-Sadi, R; Dokladny, K; Guo, S; Kaza, A; Ma, TY; Smith, MA; Watterson, DM; Ye, D1
Bertrand, C; Bueno, L; Chovet, M; Eutamene, H; Garcia-Villar, R; Salvador-Cartier, C; Schmidlin, F; Theodorou, V; Tondereau, V1

Other Studies

16 other study(ies) available for ml 7 and Disease Models, Animal

ArticleYear
Benzothiophene containing Rho kinase inhibitors: Efficacy in an animal model of glaucoma.
    Bioorganic & medicinal chemistry letters, 2010, Jun-01, Volume: 20, Issue:11

    Topics: Animals; Disease Models, Animal; Glaucoma; Haplorhini; HeLa Cells; Humans; Intraocular Pressure; Ocular Hypertension; Protein Kinase Inhibitors; rho-Associated Kinases; Thiophenes

2010
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Prescription Opioids induce Gut Dysbiosis and Exacerbate Colitis in a Murine Model of Inflammatory Bowel Disease.
    Journal of Crohn's & colitis, 2020, Jul-09, Volume: 14, Issue:6

    Topics: Analgesics, Opioid; Animals; Azepines; Disease Models, Animal; Dysbiosis; Enzyme Inhibitors; Gastrointestinal Microbiome; Hydromorphone; Inflammatory Bowel Diseases; Interleukin-10; Mice; Mice, Knockout; Myosin-Light-Chain Kinase; Naphthalenes; Pain Management

2020
Myosin light chain kinase inhibitor ML7 improves vascular endothelial dysfunction and permeability via the mitogen-activated protein kinase pathway in a rabbit model of atherosclerosis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 128

    Topics: Animals; Aorta, Thoracic; Atherosclerosis; Azepines; Diet, High-Fat; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Iliac Artery; Male; Mitogen-Activated Protein Kinases; Myosin-Light-Chain Kinase; Naphthalenes; Permeability; Phosphorylation; Plaque, Atherosclerotic; Protein Kinase Inhibitors; Rabbits; Signal Transduction; Vasodilation

2020
ML-7 attenuates airway inflammation and remodeling via inhibiting the secretion of Th2 cytokines in mice model of asthma.
    Molecular medicine reports, 2018, Volume: 17, Issue:5

    Topics: Airway Remodeling; Animals; Asthma; Azepines; Cytokines; Disease Models, Animal; Female; Inflammation; Mice; Mice, Inbred BALB C; Naphthalenes; Th2 Cells

2018
Changes in intestinal glucocorticoid sensitivity in early life shape the risk of epithelial barrier defect in maternal-deprived rats.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Analysis of Variance; Animals; Azepines; Bacterial Translocation; Colon; Colony-Forming Units Assay; Corticosterone; Dexamethasone; Dextrans; Disease Models, Animal; DNA Primers; Dose-Response Relationship, Drug; Female; Fluorescein-5-isothiocyanate; Glucocorticoids; Humans; Infant, Premature; Intestinal Mucosa; Male; Maternal Deprivation; Mifepristone; Naphthalenes; Permeability; Rats; Real-Time Polymerase Chain Reaction; Receptors, Glucocorticoid

2014
Inhibition of myosin light chain kinase reduces NADPH oxidase-mediated oxidative injury in rat brain following cerebral ischemia/reperfusion.
    Naunyn-Schmiedeberg's archives of pharmacology, 2015, Volume: 388, Issue:9

    Topics: Animals; Azepines; Brain; Brain Ischemia; Disease Models, Animal; Hydrogen Peroxide; Male; Membrane Glycoproteins; Myosin Light Chains; Myosin-Light-Chain Kinase; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Naphthalenes; Oxidative Stress; Phosphorylation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Up-Regulation

2015
[Myosin light chain kinase involved in change of intestinal mucosal barrier function in nonalcoholic steatohepatitis mice model].
    Zhonghua nei ke za zhi, 2015, Volume: 54, Issue:5

    Topics: Animals; Azepines; Disease Models, Animal; Fatty Liver; Interleukin-6; Intestinal Mucosa; Intestines; Mice; Mice, Inbred C57BL; Myosin-Light-Chain Kinase; Naphthalenes; Non-alcoholic Fatty Liver Disease; Phosphorylation; Protein Synthesis Inhibitors; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha

2015
Myosin light chain kinase inhibitor ML7 improves vascular endothelial dysfunction via tight junction regulation in a rabbit model of atherosclerosis.
    Molecular medicine reports, 2015, Volume: 12, Issue:3

    Topics: Animals; Atherosclerosis; Azepines; Diet, High-Fat; Disease Models, Animal; Endothelium, Vascular; Lipid Metabolism; Lipids; Male; Myosin-Light-Chain Kinase; Naphthalenes; Occludin; Phosphorylation; Rabbits; Tight Junctions; Zonula Occludens-1 Protein

2015
[Protective effect of myosin light-chain kinase inhibitor on acute lung injury].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2009, Volume: 21, Issue:4

    Topics: Acute Lung Injury; Animals; Azepines; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Female; Humans; Lipopolysaccharides; Lung; Mice; Mice, Inbred BALB C; Myosin-Light-Chain Kinase; Naphthalenes

2009
Vasoactive intestinal peptide ameliorates intestinal barrier disruption associated with Citrobacter rodentium-induced colitis.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Azepines; Bacterial Adhesion; Bacterial Translocation; Caco-2 Cells; Citrobacter rodentium; Claudin-3; Colitis; Colon; Disease Models, Animal; Enterobacteriaceae Infections; Humans; Injections, Intraperitoneal; Intestinal Mucosa; Mannitol; Membrane Proteins; Mice; Mice, Inbred C57BL; Myosin Light Chains; Myosin-Light-Chain Kinase; Naphthalenes; Occludin; Permeability; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Tight Junctions; Time Factors; Vasoactive Intestinal Peptide; Zonula Occludens-1 Protein

2009
Inhibition of myosin light chain kinase reduces brain edema formation after traumatic brain injury.
    Journal of neurochemistry, 2010, Volume: 112, Issue:4

    Topics: Animals; Azepines; Blood-Brain Barrier; Brain Edema; Brain Injuries; Constriction; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Evans Blue; Functional Laterality; Gene Expression Regulation; Intracranial Pressure; Male; Mice; Mice, Inbred C57BL; Myosin Light Chains; Myosin-Light-Chain Kinase; Naphthalenes; Neurologic Examination; Statistics, Nonparametric; Time Factors

2010
Transforming growth factor-β1 promotes nasal mucosal mast cell chemotaxis in murine experimental allergic rhinitis.
    ORL; journal for oto-rhino-laryngology and its related specialties, 2012, Volume: 74, Issue:3

    Topics: ADP Ribose Transferases; Animals; Azepines; Botulinum Toxins; Chemotaxis; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Female; Mast Cells; Mice; Mice, Inbred BALB C; Naphthalenes; Nasal Mucosa; Ovalbumin; Rhinitis, Allergic, Perennial; rhoA GTP-Binding Protein; Smad2 Protein; Specific Pathogen-Free Organisms; Transforming Growth Factor beta1

2012
Mechanism of interleukin-1β induced-increase in mouse intestinal permeability in vivo.
    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2012, Volume: 32, Issue:10

    Topics: Animals; Azepines; Caco-2 Cells; Crohn Disease; Dextrans; Disease Models, Animal; Enterocytes; Humans; Interleukin-1beta; Intestines; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myosin-Light-Chain Kinase; Naphthalenes; Permeability; RNA, Small Interfering; Tight Junctions; Transcription Factor RelA; Transcriptional Activation; Up-Regulation

2012
LPS-induced lung inflammation is linked to increased epithelial permeability: role of MLCK.
    The European respiratory journal, 2005, Volume: 25, Issue:5

    Topics: Animals; Azepines; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Humans; Lipopolysaccharides; Lung; Male; Myosin-Light-Chain Kinase; Naphthalenes; Permeability; Peroxidase; Pneumonia; Rats; Rats, Wistar; Reference Values; Respiratory Mucosa

2005