Page last updated: 2024-10-31

ml 7 and Brain Edema

ml 7 has been researched along with Brain Edema in 3 studies

ML-7 : An N-sulfonyldiazepane resullting from the formal condensation of 5-iodo-1-naphthylsulfonic acid with one of the nitrogens of 1,4-diazepane. It is a selective inhibitor of myosin light chain kinase (EC 2.7.11.18).

Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rossi, JL1
Todd, T1
Bazan, NG1
Belayev, L1
Luh, C1
Kuhlmann, CR2
Ackermann, B1
Timaru-Kast, R1
Luhmann, HJ2
Behl, C2
Werner, C1
Engelhard, K1
Thal, SC1
Tamaki, R1
Gamerdinger, M1
Lessmann, V1
Kempski, OS1

Other Studies

3 other studies available for ml 7 and Brain Edema

ArticleYear
Inhibition of Myosin light-chain kinase attenuates cerebral edema after traumatic brain injury in postnatal mice.
    Journal of neurotrauma, 2013, Oct-01, Volume: 30, Issue:19

    Topics: Albumins; Animals; Azepines; Behavior, Animal; Blood-Brain Barrier; Brain Edema; Brain Injuries; Col

2013
Inhibition of myosin light chain kinase reduces brain edema formation after traumatic brain injury.
    Journal of neurochemistry, 2010, Volume: 112, Issue:4

    Topics: Animals; Azepines; Blood-Brain Barrier; Brain Edema; Brain Injuries; Constriction; Disease Models, A

2010
Inhibition of the myosin light chain kinase prevents hypoxia-induced blood-brain barrier disruption.
    Journal of neurochemistry, 2007, Volume: 102, Issue:2

    Topics: Acetophenones; Animals; Astrocytes; Azepines; Blood-Brain Barrier; Brain Edema; Cattle; Cells, Cultu

2007