ml 7 has been researched along with Brain Edema in 3 studies
ML-7 : An N-sulfonyldiazepane resullting from the formal condensation of 5-iodo-1-naphthylsulfonic acid with one of the nitrogens of 1,4-diazepane. It is a selective inhibitor of myosin light chain kinase (EC 2.7.11.18).
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 2 (66.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Rossi, JL | 1 |
Todd, T | 1 |
Bazan, NG | 1 |
Belayev, L | 1 |
Luh, C | 1 |
Kuhlmann, CR | 2 |
Ackermann, B | 1 |
Timaru-Kast, R | 1 |
Luhmann, HJ | 2 |
Behl, C | 2 |
Werner, C | 1 |
Engelhard, K | 1 |
Thal, SC | 1 |
Tamaki, R | 1 |
Gamerdinger, M | 1 |
Lessmann, V | 1 |
Kempski, OS | 1 |
3 other studies available for ml 7 and Brain Edema
Article | Year |
---|---|
Inhibition of Myosin light-chain kinase attenuates cerebral edema after traumatic brain injury in postnatal mice.
Topics: Albumins; Animals; Azepines; Behavior, Animal; Blood-Brain Barrier; Brain Edema; Brain Injuries; Col | 2013 |
Inhibition of myosin light chain kinase reduces brain edema formation after traumatic brain injury.
Topics: Animals; Azepines; Blood-Brain Barrier; Brain Edema; Brain Injuries; Constriction; Disease Models, A | 2010 |
Inhibition of the myosin light chain kinase prevents hypoxia-induced blood-brain barrier disruption.
Topics: Acetophenones; Animals; Astrocytes; Azepines; Blood-Brain Barrier; Brain Edema; Cattle; Cells, Cultu | 2007 |