ml 7 has been researched along with Atherosclerosis in 4 studies
ML-7 : An N-sulfonyldiazepane resullting from the formal condensation of 5-iodo-1-naphthylsulfonic acid with one of the nitrogens of 1,4-diazepane. It is a selective inhibitor of myosin light chain kinase (EC 2.7.11.18).
Atherosclerosis: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "HFD-fed rabbits showed typical atheromatous lesions and endothelial hyperpermeability, and these lesions could be partly reversed following ML7 therapy." | 1.56 | Myosin light chain kinase inhibitor ML7 improves vascular endothelial dysfunction and permeability via the mitogen-activated protein kinase pathway in a rabbit model of atherosclerosis. ( Ding, J; Ding, Y; Gui, S; Li, L; Li, Z; Meng, S; Wang, D; Wang, Y; Wei, W; Zhou, Q; Zhu, H, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ding, J | 1 |
| Li, Z | 1 |
| Li, L | 1 |
| Ding, Y | 1 |
| Wang, D | 1 |
| Meng, S | 1 |
| Zhou, Q | 3 |
| Gui, S | 1 |
| Wei, W | 1 |
| Zhu, H | 2 |
| Wang, Y | 4 |
| Wang, J | 1 |
| Zhang, C | 1 |
| Li, C | 1 |
| Zhao, D | 1 |
| Li, S | 1 |
| Ma, L | 1 |
| Cui, Y | 1 |
| Wei, X | 1 |
| Zhao, Y | 1 |
| Gao, Y | 1 |
| Zhu, HQ | 1 |
| Wang, XB | 1 |
| Han, JX | 1 |
| Hu, ZP | 1 |
| Gui, SY | 1 |
| Cheng, X | 1 |
| Wang, X | 1 |
| Wan, Y | 1 |
4 other studies available for ml 7 and Atherosclerosis
| Article | Year |
|---|---|
Myosin light chain kinase inhibitor ML7 improves vascular endothelial dysfunction and permeability via the mitogen-activated protein kinase pathway in a rabbit model of atherosclerosis.
Topics: Animals; Aorta, Thoracic; Atherosclerosis; Azepines; Diet, High-Fat; Disease Models, Animal; Endothe | 2020 |
MicroRNA-92a promotes vascular smooth muscle cell proliferation and migration through the ROCK/MLCK signalling pathway.
Topics: Animals; Atherosclerosis; Azepines; Becaplermin; Cell Movement; Cell Proliferation; Enzyme Inhibitor | 2019 |
Myosin light chain kinase inhibitor attenuates atherosclerosis and permeability via reduced endothelial tight junction in rabbits.
Topics: Animals; Aorta; Atherosclerosis; Azepines; Blotting, Western; Endothelium, Vascular; Immunohistochem | 2013 |
Myosin light chain kinase inhibitor ML7 improves vascular endothelial dysfunction via tight junction regulation in a rabbit model of atherosclerosis.
Topics: Animals; Atherosclerosis; Azepines; Diet, High-Fat; Disease Models, Animal; Endothelium, Vascular; L | 2015 |