Page last updated: 2024-10-31

ml 7 and Asthma

ml 7 has been researched along with Asthma in 3 studies

ML-7 : An N-sulfonyldiazepane resullting from the formal condensation of 5-iodo-1-naphthylsulfonic acid with one of the nitrogens of 1,4-diazepane. It is a selective inhibitor of myosin light chain kinase (EC 2.7.11.18).

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, C1
Zhang, Z1
Wang, L1
Liu, J1
Gong, X1
Zhang, C1
Connolly, SC1
Smith, PG1
Fairbank, NJ1
Lall, CA1
Cole, DJ1
Mackinnon, JD1
Maksym, GN1
Raqeeb, A1
Jiao, Y1
Syyong, HT1
Paré, PD1
Seow, CY1

Other Studies

3 other studies available for ml 7 and Asthma

ArticleYear
ML-7 attenuates airway inflammation and remodeling via inhibiting the secretion of Th2 cytokines in mice model of asthma.
    Molecular medicine reports, 2018, Volume: 17, Issue:5

    Topics: Airway Remodeling; Animals; Asthma; Azepines; Cytokines; Disease Models, Animal; Female; Inflammatio

2018
Chronic oscillatory strain induces MLCK associated rapid recovery from acute stretch in airway smooth muscle cells.
    Journal of applied physiology (Bethesda, Md. : 1985), 2011, Volume: 111, Issue:4

    Topics: Animals; Asthma; Azepines; Cells, Cultured; Dogs; Muscle Contraction; Muscle, Smooth; Myocytes, Smoo

2011
Regulatable stiffness in relaxed airway smooth muscle: a target for asthma treatment?
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:3

    Topics: Amides; Animals; Asthma; Azepines; Calcium; Imidazoles; In Vitro Techniques; Molecular Targeted Ther

2012