ml 7 has been researched along with Asthma in 3 studies
ML-7 : An N-sulfonyldiazepane resullting from the formal condensation of 5-iodo-1-naphthylsulfonic acid with one of the nitrogens of 1,4-diazepane. It is a selective inhibitor of myosin light chain kinase (EC 2.7.11.18).
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, C | 1 |
| Zhang, Z | 1 |
| Wang, L | 1 |
| Liu, J | 1 |
| Gong, X | 1 |
| Zhang, C | 1 |
| Connolly, SC | 1 |
| Smith, PG | 1 |
| Fairbank, NJ | 1 |
| Lall, CA | 1 |
| Cole, DJ | 1 |
| Mackinnon, JD | 1 |
| Maksym, GN | 1 |
| Raqeeb, A | 1 |
| Jiao, Y | 1 |
| Syyong, HT | 1 |
| Paré, PD | 1 |
| Seow, CY | 1 |
3 other studies available for ml 7 and Asthma
| Article | Year |
|---|---|
ML-7 attenuates airway inflammation and remodeling via inhibiting the secretion of Th2 cytokines in mice model of asthma.
Topics: Airway Remodeling; Animals; Asthma; Azepines; Cytokines; Disease Models, Animal; Female; Inflammatio | 2018 |
Chronic oscillatory strain induces MLCK associated rapid recovery from acute stretch in airway smooth muscle cells.
Topics: Animals; Asthma; Azepines; Cells, Cultured; Dogs; Muscle Contraction; Muscle, Smooth; Myocytes, Smoo | 2011 |
Regulatable stiffness in relaxed airway smooth muscle: a target for asthma treatment?
Topics: Amides; Animals; Asthma; Azepines; Calcium; Imidazoles; In Vitro Techniques; Molecular Targeted Ther | 2012 |