Page last updated: 2024-09-04

ml-3000 and Inflammation

ml-3000 has been researched along with Inflammation in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's6 (54.55)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Aidhen, IS; Doble, M; Ramanan, M; Sinha, S; Sudarshan, K1
Balansky, R; De Flora, S; Izzotti, A; La Maestra, S; Micale, RT; Pulliero, A1
Kaur, G; Silakari, O1
Poorvashree, J; Suneela, D1
Meirer, K; Proschak, E; Steinhilber, D1
Chen, H; Wu, YJ; Xue, M1
Dulin, JN; Grill, RJ; Karoly, ED; Strobel, HW; Wang, Y1
Cicuttini, F; Ding, C1
Kulkarni, SK; Patil, CS; Singh, VP1
Naveau, B1
Cerletti, C; Dell'Elba, G; Evangelista, V; Manarini, S; Rotondo, S1

Reviews

3 review(s) available for ml-3000 and Inflammation

ArticleYear
Multiple target-centric strategy to tame inflammation.
    Future medicinal chemistry, 2017, Volume: 9, Issue:12

    Topics: Cyclooxygenase Inhibitors; Humans; Inflammation; Lactones; Lipoxygenase; Lipoxygenase Inhibitors; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Pyrroles; Structure-Activity Relationship; Sulfones

2017
Inhibitors of the arachidonic acid cascade: interfering with multiple pathways.
    Basic & clinical pharmacology & toxicology, 2014, Volume: 114, Issue:1

    Topics: Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cyclooxygenase 2 Inhibitors; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Humans; Inflammation; Lipoxygenase Inhibitors; Pain; Pyrroles

2014
Licofelone (Merckle).
    IDrugs : the investigational drugs journal, 2003, Volume: 6, Issue:8

    Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclooxygenase Inhibitors; Humans; Inflammation; Lipoxygenase Inhibitors; Osteoarthritis; Pyrroles; Structure-Activity Relationship

2003

Other Studies

8 other study(ies) available for ml-3000 and Inflammation

ArticleYear
Inhibition of the enzymes in the leukotriene and prostaglandin pathways in inflammation by 3-aryl isocoumarins.
    European journal of medicinal chemistry, 2016, Nov-29, Volume: 124

    Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cytokines; Dinoprostone; Free Radicals; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Inflammation; Isocoumarins; Kinetics; Leukotrienes; Lipoxygenase Inhibitors; Prostaglandins; RNA, Messenger

2016
Modulation of smoke-induced DNA and microRNA alterations in mouse lung by licofelone, a triple COX-1, COX-2 and 5-LOX inhibitor.
    Carcinogenesis, 2020, 03-13, Volume: 41, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Arachidonate 5-Lipoxygenase; Carcinogenesis; Cyclooxygenase 1; Cyclooxygenase 2; Disease Models, Animal; DNA Adducts; DNA Damage; Drug Administration Schedule; Female; Humans; Inflammation; Lung; Lung Neoplasms; Male; Membrane Proteins; Mice; MicroRNAs; Pyrroles; Time Factors; Tobacco Smoke Pollution; Toxicity Tests, Subchronic

2020
Novel drug delivery of dual acting prodrugs of hydroxychloroquine with aryl acetic acid NSAIDs: Design, kinetics and pharmacological study.
    Drug delivery and translational research, 2017, Volume: 7, Issue:5

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Carrageenan; Diclofenac; Drug Design; Female; Freund's Adjuvant; Hydroxychloroquine; Inflammation; Male; Mice; Prodrugs; Pyrroles; Rats; Rats, Wistar

2017
Licofelone inhibits interleukin-18-induced pro-inflammatory cytokine release and cellular proliferation in human mesangial cells.
    Basic & clinical pharmacology & toxicology, 2012, Volume: 111, Issue:3

    Topics: Arachidonate 5-Lipoxygenase; Blotting, Western; Cell Line; Cell Proliferation; Chemokine CCL2; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Interferon-gamma; Interleukin-18; Lipoxygenase Inhibitors; Mesangial Cells; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyrroles; Signal Transduction

2012
Licofelone modulates neuroinflammation and attenuates mechanical hypersensitivity in the chronic phase of spinal cord injury.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Jan-09, Volume: 33, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Gas Chromatography-Mass Spectrometry; Hindlimb; Hot Temperature; Hyperalgesia; Inflammation; Leukotriene B4; Locomotion; Metabolomics; Oxidative Stress; Physical Stimulation; Pyrroles; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

2013
Effect of licofelone against NSAIDs-induced gastrointestinal ulceration and inflammation.
    Indian journal of experimental biology, 2005, Volume: 43, Issue:3

    Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Female; Humans; Indomethacin; Inflammation; Leukotriene B4; Lipid Peroxidation; Male; Mesentery; Mice; Neutrophils; Pyrroles; Rats; Stomach Ulcer; Time Factors

2005
Dual inhibition of cyclo-oxygenases and 5-lipoxygenase: a novel therapeutic approach to inflammation?
    Joint bone spine, 2005, Volume: 72, Issue:3

    Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Inflammation; Lipoxygenase Inhibitors; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrroles

2005
The lipoxygenase-cyclooxygenase inhibitor licofelone prevents thromboxane A2-mediated cardiovascular derangement triggered by the inflammatory peptide fMLP in the rabbit.
    European journal of pharmacology, 2006, Sep-28, Volume: 546, Issue:1-3

    Topics: Acetates; Animals; Aspirin; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Electrocardiography; Heart Rate; Inflammation; Lactones; Leukotriene B4; Lipoxygenase Inhibitors; Male; Myocardial Ischemia; N-Formylmethionine Leucyl-Phenylalanine; Pyrroles; Rabbits; Sulfones; Thromboxane A2; Time Factors

2006