Page last updated: 2024-09-04

ml-3000 and Colonic Neoplasms

ml-3000 has been researched along with Colonic Neoplasms in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brewer, M; Janakiram, NB; Mohammed, A; Rao, CV; Steele, VE; Vedala, K1
Choi, CI; Janakiram, NB; Li, Q; Mohammed, A; Rao, CV; Steele, VE; Zhang, Y1
Chieco, P; Guarnieri, T; Laufer, S; Munarini, A; Storci, G; Tavolari, S1
Bartolini, G; Bonafè, M; Brighenti, E; Ferreri, C; Guarnieri, T; Laufer, S; Manara, S; Marini, M; Tavolari, S; Tomasi, V1

Other Studies

4 other study(ies) available for ml-3000 and Colonic Neoplasms

ArticleYear
Multitargeted low-dose GLAD combination chemoprevention: a novel and promising approach to combat colon carcinogenesis.
    Neoplasia (New York, N.Y.), 2013, Volume: 15, Issue:5

    Topics: Adenomatous Polyps; Animals; Antineoplastic Combined Chemotherapy Protocols; Atorvastatin; Carcinogenesis; Cell Proliferation; Chemoprevention; Colon; Colonic Neoplasms; Cytokines; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Eflornithine; Female; Gefitinib; Heptanoic Acids; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Targeted Therapy; Pyrroles; Quinazolines

2013
Chemoprevention of colon and small intestinal tumorigenesis in APC(Min/+) mice by licofelone, a novel dual 5-LOX/COX inhibitor: potential implications for human colon cancer prevention.
    Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:12

    Topics: Adenomatous Polyposis Coli Protein; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Blotting, Western; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Female; Humans; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Pyrroles; Real-Time Polymerase Chain Reaction; RNA, Messenger

2011
The decrease of cell membrane fluidity by the non-steroidal anti-inflammatory drug Licofelone inhibits epidermal growth factor receptor signalling and triggers apoptosis in HCA-7 colon cancer cells.
    Cancer letters, 2012, Aug-28, Volume: 321, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Membrane; Cell Survival; Colonic Neoplasms; ErbB Receptors; Fluorescent Antibody Technique; Humans; Membrane Fluidity; Mitogen-Activated Protein Kinases; Pyrroles; Signal Transduction

2012
Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade.
    Carcinogenesis, 2008, Volume: 29, Issue:2

    Topics: Acetates; Apoptosis; Arachidonic Acid; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cyclooxygenase Inhibitors; Cytosol; Gene Expression Regulation, Neoplastic; Humans; Lipoxygenase Inhibitors; Membrane Potential, Mitochondrial; Mitochondria; Prostaglandin-Endoperoxide Synthases; Pyrroles

2008