mk 436 has been researched along with Chagas Disease in 5 studies
*Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Habbersett, MC; Meurer, RD; Murray, PK | 1 |
| Calixto, MA; Teixeira, AR; Teixeira, ML | 1 |
| Cunha Neto, E; Rizzo, LV; Silva, R; Teixeira, AR | 1 |
| Andrade, SG; Santiago, CM; Silva, RC | 1 |
| Andrade, SG; Freitas, LA; Santiago, CM; Silva, RC | 1 |
5 other study(ies) available for mk 436 and Chagas Disease
| Article | Year |
|---|---|
Trypanosoma cruzi: efficacy of the 2-substituted, 5-nitroimidazoles, MK-436 and L634,549, in tissue culture and mice.
Topics: Animals; Antiprotozoal Agents; Benzimidazoles; Cell Line; Chagas Disease; Drug Evaluation, Preclinical; Female; Fibroblasts; Humans; Mice; Mice, Inbred BALB C; Muscles; Nifurtimox; Nitroimidazoles; Rats; Trypanosoma cruzi | 1983 |
Chagas' disease: carcinogenic activity of the antitrypanosomal nitroarenes in mice.
Topics: Animals; Carcinogens; Cell Division; Chagas Disease; Female; Liver; Lymph Nodes; Lymphoma; Mice; Molecular Structure; Nifurtimox; Nitroimidazoles; Trypanocidal Agents | 1994 |
Trypanocidal nitroarene treatment of experimental Trypanosoma cruzi infection does not prevent progression of chronic-phase heart lesions in rabbits.
Topics: Animals; Chagas Cardiomyopathy; Chagas Disease; Nifurtimox; Nitroimidazoles; Rabbits; Trypanocidal Agents | 1990 |
Treatment of chronic experimental Trypanosoma cruzi infections in mice with MK-436, a 2-substituted 5-nitroimidazole.
Topics: Animals; Antiprotozoal Agents; Chagas Disease; Drug Evaluation, Preclinical; Mice; Nitroimidazoles | 1989 |
Therapeutic action of MK-436 (2,5-nitroimidazole) on Trypanosoma cruzi infections in mice: a parasitological, serological, histopathological, and ultrastructural study.
Topics: Animals; Chagas Cardiomyopathy; Chagas Disease; Disease Models, Animal; Female; Male; Mice; Myocardium; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi | 1987 |