mk-2206 has been researched along with Myocardial-Infarction* in 1 studies
1 other study(ies) available for mk-2206 and Myocardial-Infarction
| Article | Year |
|---|---|
Augmentation of Ouabain-Induced Increase in Heart Muscle Contractility by Akt Inhibitor MK-2206.
Cardiac steroids (CSs), such as ouabain and digoxin, increase the force of contraction of heart muscle and are used for the treatment of congestive heart failure (CHF). However, their small therapeutic window limits their use. It is well established that Na Topics: Animals; Cardiotonic Agents; Cells, Cultured; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Heterocyclic Compounds, 3-Ring; Isolated Heart Preparation; Male; Myocardial Contraction; Myocardial Infarction; Myocytes, Cardiac; Ouabain; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats, Wistar; Signal Transduction; Ventricular Function, Left | 2019 |