Page last updated: 2024-08-24

mk 0591 and Asthma

mk 0591 has been researched along with Asthma in 5 studies

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (60.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	1 (20.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Arruda, JM; Baccei, C; Bain, G; Chapman, C; Correa, L; Darlington, J; Evans, JF; Hutchinson, JH; King, CD; Lee, C; Li, Y; Lorrain, D; Prasit, P; Prodanovich, P; Rong, H; Santini, A; Stock, N	1
Davidsson, Ö; Pettersen, D; Whatling, C	1
Bajwa, K; Becker, AB; Black, C; Ford-Hutchinson, AW; Lilley, MK; Simons, FE; Tagari, P	1
Bel, EH; De Smet, M; Depré, M; Diamant, Z; Friedman, BS; Hilliard, D; Sterk, PJ; Timmers, MC; van der Veen, H	1
Becker, A; Brideau, C; Ford-Hutchinson, A; Frenette, R; Sadl, V; Tagari, P; Thomas, E; Vickers, P	1

Reviews

1 review(s) available for mk 0591 and Asthma

Article	Year
Recent advances for FLAP inhibitors. Bioorganic & medicinal chemistry letters, 2015, Jul-01, Volume: 25, Issue:13 Topics: 5-Lipoxygenase-Activating Protein Inhibitors; Animals; Asthma; Atherosclerosis; Drug Design; Drug Discovery; Humans; Inflammation; Leukotrienes; Molecular Structure	2015

Trials

1 trial(s) available for mk 0591 and Asthma

Article	Year
The effect of MK-0591, a novel 5-lipoxygenase activating protein inhibitor, on leukotriene biosynthesis and allergen-induced airway responses in asthmatic subjects in vivo. The Journal of allergy and clinical immunology, 1995, Volume: 95, Issue:1 Pt 1 Topics: 5-Lipoxygenase-Activating Proteins; Administration, Oral; Adult; Allergens; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Carrier Proteins; Creatinine; Double-Blind Method; Forced Expiratory Volume; Histamine; Humans; Indoles; Leukotriene Antagonists; Leukotrienes; Male; Membrane Proteins; Quinolines; Time Factors	1995

Article

Year

The effect of MK-0591, a novel 5-lipoxygenase activating protein inhibitor, on leukotriene biosynthesis and allergen-induced airway responses in asthmatic subjects in vivo.

The Journal of allergy and clinical immunology, 1995, Volume: 95, Issue:1 Pt 1

Topics: 5-Lipoxygenase-Activating Proteins; Administration, Oral; Adult; Allergens; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Carrier Proteins; Creatinine; Double-Blind Method; Forced Expiratory Volume; Histamine; Humans; Indoles; Leukotriene Antagonists; Leukotrienes; Male; Membrane Proteins; Quinolines; Time Factors

1995

Other Studies

3 other study(ies) available for mk 0591 and Asthma

Article	Year
5-lipoxygenase-activating protein inhibitors: development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103). Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19 Topics: 5-Lipoxygenase-Activating Proteins; Animals; Asthma; Carrier Proteins; Dogs; Drug-Related Side Effects and Adverse Reactions; Heterocyclic Compounds; Humans; Indoles; Inhibitory Concentration 50; Leukotriene B4; Membrane Proteins; Mice; Propionates; Protein Binding; Rats; Structure-Activity Relationship	2009
Antiasthmatic effects of a leukotriene biosynthesis inhibitor (MK-0591) in allergic dogs. Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 78, Issue:2 Topics: 5-Lipoxygenase-Activating Proteins; Airway Resistance; Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Carrier Proteins; Dogs; Histamine; Indoles; Leukotriene Antagonists; Leukotriene B4; Leukotriene E4; Leukotrienes; Membrane Proteins; Quinolines; Respiratory Hypersensitivity	1995
Leukotriene generation and metabolism in dogs: inhibition of biosynthesis by MK-0591. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:1 Topics: 5-Lipoxygenase-Activating Proteins; Animals; Asthma; Carrier Proteins; Disease Models, Animal; Dogs; Indoles; Leukotriene Antagonists; Leukotriene E4; Leukotrienes; Membrane Proteins; Quinolines; SRS-A	1993